Zobrazeno 1 - 10
of 33
pro vyhledávání: '"S E Knowles"'
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Successful implementation of digital health systems requires contextually sensitive solutions. Working directly with system users and drawing on implementation science frameworks are both recommended. We sought to combine Normalis
Externí odkaz:
https://doaj.org/article/ee94169ca35c45689e1f1b3d0a3c3a4c
Autor:
P. A. Grant, S. E. Knowles, K Irvine, O Gajanandana, Phillip C. Owens, G L Francis, Joseph W. Wrin, John C. Wallace
Publikováno v:
Journal of Endocrinology. 156:407-414
Long-Arg3-IGF-I (LR3IGF-I) is a synthetic analog of IGF-I that has much lower affinity for IGF-binding proteins than do native IGFs-I and -II. Comparisons of the effects of LR3IGF-I with those of IGFs-I and-II in in vitro and in vivo studies have pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fa0a8b116b65c2204a23ca74fb2987
https://doi.org/10.1677/joe.0.1560407
https://doi.org/10.1677/joe.0.1560407
Autor:
Phillip C. Owens, K Kita, Briony E. Forbes, R Hughes, S. E. Knowles, F. J. Ballard, F M Tomas, Zee Upton
Publikováno v:
Scopus-Elsevier
We have examined the influence of nutrition on plasma IGF-I, IGF-II and IGF-binding protein (IGFBP) levels and on hepatic IGF-I gene expression in young meat-type chickens. Plasma IGF concentrations were measured by using RIA with recombinant chicken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2685ded78039600a8ac97ec348964f6
https://doi.org/10.1677/joe.0.1490181
https://doi.org/10.1677/joe.0.1490181
Publikováno v:
Acta Horticulturae. :483-486
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ace1ecaeb883bb2e9e74e095a08f9e7
https://doi.org/10.17660/actahortic.1995.384.76
https://doi.org/10.17660/actahortic.1995.384.76
Publikováno v:
New Zealand Journal of Crop and Horticultural Science. 22:419-430
The apricot cultivar ‘Sundrop’ (Prunus armeniaca L.) was planted on 23 different rootstocks at the Clyde Research Centre, Alexandra, New Zealand. Rootstock influence was assessed over a period of 9 years using the following criteria: tree surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35278cf944a53bb0fb4ca7798541725a
https://doi.org/10.1080/01140671.1994.9513854
https://doi.org/10.1080/01140671.1994.9513854
Publikováno v:
Biochemical Journal. 291:781-786
The effects of graded doses of insulin-like growth factor-I (IGF-I) and two variants which bind poorly to IGF-binding proteins were investigated in 160 g streptozotocin-induced diabetic rats. The two variants were the truncated form, des(1-3)IGF-I, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35b77d3ab8ae064de4e21b153a0d243
https://doi.org/10.1042/bj2910781
https://doi.org/10.1042/bj2910781
Autor:
C S Chandler, G L Francis, S E Knowles, P. C. Owens, F. M. Tomas, F J Ballard, Leanna C. Read
Publikováno v:
Biochemical Journal. 282:91-97
The administration of insulin-like growth factor-I (IGF-I) via subcutaneously implanted osmotic pumps partially reversed a catabolic state produced by the co-administration of 20 micrograms of dexamethasone/day to 150 g male rats. Marked dose-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fee41f4d43f03e36a6ead986cda12d
https://doi.org/10.1042/bj2820091
https://doi.org/10.1042/bj2820091
Publikováno v:
Ciba Foundation Symposium 75-Protein Degradation in Health and Disease
In experiments involving a range of cultured mammalian cells derived from several different tissues we have shown that lysosomotropic agents such as proteolytic inhibitors or weak bases are only able to reduce intracellular protein breakdown by about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a088755728dee1e28275af232cb68092
https://doi.org/10.1002/9780470720585.ch8
https://doi.org/10.1002/9780470720585.ch8
Publikováno v:
Diabetes. 45(2)
Studies in diabetic rodents and humans provide evidence that IGF-I may alleviate the diabetic state and insulin resistance to some degree. To assess the efficacy of IGFs as an adjunct treatment with insulin in diabetes, we infused IGF-I or des(1–3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be16fbb8dc47fd20e6f67cfc0c4d2a13
https://pubmed.ncbi.nlm.nih.gov/8549861
https://pubmed.ncbi.nlm.nih.gov/8549861
Publikováno v:
The American journal of physiology. 261(4 Pt 2)
The efficacy of insulin-like growth factor I (IGF-I) in enhancing growth in animals with reduced renal mass was investigated in subtotally nephrectomized young male rats. Recombinant human IGF-I was administered by osmotic minipumps for 7 days at two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb173137306d8ec6a04f57cabc79ac
https://pubmed.ncbi.nlm.nih.gov/1928375
https://pubmed.ncbi.nlm.nih.gov/1928375