Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S E, Shehin"'
Autor:
David E. Williams, Mei-Fei Yueh, Ronald N. Hines, S. E. Shehin, Min-Young Lee, S. Larsen-Su, Sharon K. Krueger
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 13:187-193
Mammalian flavin-containing monooxygenase functions in the oxygenation of numerous xenobiotics containing a soft nucleophile, usually a nitrogen or sulfur. A total of five distinct flavin monooxygenase (FMO) isoforms are expressed in mammals. Individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea886596888fcd4df111a01aaf3705f
https://doi.org/10.1002/(sici)1099-0461(1999)13:3/4<187::aid-jbt9>3.0.co
https://doi.org/10.1002/(sici)1099-0461(1999)13:3/4<187::aid-jbt9>3.0.co
Publikováno v:
The Journal of biological chemistry. 275(10)
The cytochrome P450 1B1 gene (CYP1B1) is expressed constitutively and is inducible by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the human breast adenocarcinoma cell line MCF-7 but not in the human hepatoma cell line HepG2. Genomic DNA isolated fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3928f63f69c8956cac68922945b9093c
https://pubmed.ncbi.nlm.nih.gov/10702233
https://pubmed.ncbi.nlm.nih.gov/10702233
Publikováno v:
Journal of biochemical and molecular toxicology. 13(3-4)
Mammalian flavin-containing monooxygenase functions in the oxygenation of numerous xenobiotics containing a soft nucleophile, usually a nitrogen or sulfur. A total of five distinct flavin monooxygenase (FMO) isoforms are expressed in mammals. Individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9322ad2e0ece6907cbf0f36641f456b
https://pubmed.ncbi.nlm.nih.gov/10098904
https://pubmed.ncbi.nlm.nih.gov/10098904
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(1)
The purpose of this study was to examine whether intracellular metallothionein (MT) protects against acetaminophen hepatotoxicity. MT-I/II knockout (MT-null) and control mice were given acetaminophen (150-500 mg/kg i.p.), and liver injury was assesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9da59d43cbb00c6bda9832edd16dce88
https://pubmed.ncbi.nlm.nih.gov/10087053
https://pubmed.ncbi.nlm.nih.gov/10087053
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(8)
Previous studies demonstrated that the flavin-containing monooxygenases (FMO) are expressed in a tissue-specific manner. To begin an elucidation of mechanisms regulating this expression pattern, genomic clones for rabbit FMO2 were isolated and charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39a1cb39606592e52b261d8a0e4d776c
https://pubmed.ncbi.nlm.nih.gov/8869825
https://pubmed.ncbi.nlm.nih.gov/8869825
Publikováno v:
Comparative biochemistry and physiology. Part C, Pharmacology, toxicologyendocrinology. 112(2)
N,N-Dimethylaniline (DMA) N -oxidase activity indicative of flavin-containing monooxygenase (FMO) was examined in four tissues (liver, gill, muscle, and kidney) of the flounder ( Platichthys flesus ). Gill microsomes had the highest levels of activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e997824901ec797270ab8fb4a5bcc6
https://pubmed.ncbi.nlm.nih.gov/8788588
https://pubmed.ncbi.nlm.nih.gov/8788588
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(3)
The microsomal flavin-containing monooxygenases (FMO) represent a family of xenobiotic-metabolizing enzymes with distinct tissue- and species-specific patterns of expression. Expression for two FMO isoforms (FMO1 and FMO2) in rabbit was characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::352ec2784449ae16b2360261aca6e973
https://pubmed.ncbi.nlm.nih.gov/7891346
https://pubmed.ncbi.nlm.nih.gov/7891346
Publikováno v:
Biochemical and biophysical research communications. 172(2)
The potential for enhanced translational processing of P450IIE1 mRNA during the early phase of P450IIE1 induction by pyridine or acetone was assessed by hybridization analysis of polyribosomal P450IIE1 mRNA distribution in rat hepatic tissue. Optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6344e47102673fabc820f77c106f5d
https://pubmed.ncbi.nlm.nih.gov/2241968
https://pubmed.ncbi.nlm.nih.gov/2241968
Publikováno v:
The Canadian journal of cardiology. 3(4)
Mice implanted with chronic indwelling cannulae were injected into the lateral cerebral ventricle with two adenosine analogs, NECA and L-PIA, and the effects on blood pressure and heart rate recorded. Both analogs produced dose-related reductions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5d745b5f9786c011c5a2aede04b1fe4
https://pubmed.ncbi.nlm.nih.gov/3594302
https://pubmed.ncbi.nlm.nih.gov/3594302