Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP

Autor: H, Li, D M, Macdonald, X, Hronowski, C E, Costello, S E, Leeman, N D, Boyd

Publikováno v: The Journal of biological chemistry. 276(14)

The covalent attachment site of a substance P (SP) analogue containing the photoreactive amino acid p-benzoyl-l-phenylalanine (Bpa) in position 8 of the C-terminal portion of the peptide was identified previously as Met-181 on the neurokinin-1 (NK-1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::823352bfcada0445d7df77ae6b59f4ae
https://pubmed.ncbi.nlm.nih.gov/11116140

Photoaffinity labeling of the human substance P (neurokinin-1) receptor with [3H2]azido-CP-96,345, a photoreactive derivative of a nonpeptide antagonist

Autor: D, MacDonald, S C, Silberman, J A, Lowe, S E, Drozda, S E, Leeman, N D, Boyd

Publikováno v: Molecular pharmacology. 49(5)

An azido derivative of [3H2](2S, 3S)-cis-2-(diphenylmethyl)-N-((2-methoxyphenyl) methyl)-1-azabicyclo[2.2.2]octon-3-amine (CP-96,345), a potent nonpeptide antagonist of the substance P (SP) (neurokinin-1) receptor, was synthesized and shown to have a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b138d9b61bcc91ad0c7244edaaad09b0
https://pubmed.ncbi.nlm.nih.gov/8622630

Abstracts

Autor: Lubna H. Abdullah, K. D. Buchanan, T. N. Akopyan, A. M. Arzumanyan, A. A. Arutunyan, H. Berger, P. Oehme, M. E. Atkinson, J. S. Chaggar, S. J. Bailey, R. L. Featherstone, C. C. Jordan, I. K. M. Morton, A. Balfe, P. Skrabanek, D. Powell, F. Barja, R. Mathison, H. Huggel, H. Bittiger, J. Heid, Ulla Björkroth, Sune Rosell, N. D. Boyd, M. P. Anthony, S. E. Leeman, I. Briggs, J. W. Growcott, A. Jamieson, Ann V. Tarpey, E. Brodin, B. A. Meyerson, J. R. Brown, A. G. Hayes, K. G. Meecham, M. B. Tyers, E. Burcher, G. Bynke, R. Håkanson, J. Hörig, John R. Cann, Iffat Rahim, Albert Vatter, John M. Stewart, Margaret A. Cascieri, Tehming Liang, H. J. Cheeseman, R. O. Pinnock, G. Henderson, J. Constantinidis, C. Bouras, C. H. Taban, R. Guntern, R. Couture, A. C. Cuello, C. -J. Dalsgaard, C. -E. Jonsson, J. Arvidsson, M. Risling, T. Hökfelt, M. Schultzberg, S. R. Vincent, L. -G. Elfvin, R. de Beaurepaire, S. D. Iversen, D. Delbro, B. Lisander, L. Fändriks, S. A. Andersson, M. Del Fiacco, M. L. Dessi, M. C. Levarvti, J. Del Rio, J. R. Naranjo, S. Domschke, S. R. Bloom, T. E. Adrian, G. Lux, M. G. Bryant, G. P. McGregor, W. Domschke, J. Donnerer, L. Barthó, P. Holzer, F. Lembeck, G. Skofitsch, P. J. Elliott, M. J. Bannon, J. E. Alpert, G. -L Ferri, G. McGregor, P. Vezzadini, G. Labo, J. M. Polak, J. C. Fontaine-Perus, M. Chanconie, J. C. Foreman, W. Piotrowski, J. E. T. Fox, E. E. Daniel, J. Jury, T. Domoto, I. Berezin, G. Gaudino, L. Mondardini, A. Fasolo, B. Gazelius, T. Kahan, P. Panopoulos, L. Olgart, Alan R. Gintzler, Bernard M. Jaffe, Sheri A. Baron, K. O. GrÖnstad, H. Ahlman, M. J. Zinner, B. M. Jaffe, C. Yeo, J. Gu, W. M. Huang, K. N. lslam, G. Terenghi, J. Morrison, H. -G. Güllner, Guenther Haeusler, Gail E. Handelmann, Joyce H. Selsky, R. D. Helme, D. M. White, H. Höfler, Ph. U. Heitzt, L. Auböck, Ulrike Petsche, Irmgard Lippe, Janice L. K. Hylden, George L. Wilcox, Atsuko Inoue, Yoshihiro Nakata, Tomio Segawa, B. Jakubowska-Naziemblo, E. Potargowicz, W. Z. Traczyk, D. Cannon, W. Rohde, G. JancsÓ, E. Király, S. Karcsú, A. Szebeni, E. Bácsy, R. S. G. Jones, H. -R. Olpe, D. M. Wrightt, I. Jurna, B. Kerdelhué, V. Lenoir, C. Pasqualini, A. El Abed, G. Morel, P. Dubois, P. Hublot, A. Tartar, D. Klingmúller, C. Waltz, H. J. Kramer, H. Koop, W. Luster, C. Gropp, K. Havemenn, R. Arnold, James E. Krause, Jeffrey F. McKelvy, W. Krivoy, J. Couch, F. Strand, S. Leander, K. Folkers, C. M. Lee, S. H. Snyder, P. Lindberg, A. Dahlström, J. M. Lundberg, N. Lindefors, U. Ungerstedt, L. -Y. Liu-Chen, T. Liszczak, M. R. Mayberg, M. A. Moskowitz, Jan M. Lundberg, Alois Saria, Ernst Brodin, Claes-Roland Martling, Tomas Hökfelt, Lars Lundblad, Anders Änggård, K. F. McGeeney, M. D. O'Donnell, M. A. Blank, K. Manolas, W. G. Linger, J. M. Allen, J. E. Maggio, B. E. B. Sandberg, C. V. Bradley, L. L. Iversen, S. Santikarn, D. H. Williams, J. C. Hunter, M. R. Hanley, I. Magnusson, L. Thulin, Agneta Mandahl, Anders Bill, Maurice Manning, H. Martensson, B. Akande, P. Stofer, G. Chappuis, H. Immer, P. Groog, Margaret R. Matthews, M. Connaughton, R. Moratalla, Anders Nobin, Piers Emson, Frank Sundler, T. L. O'Donohue, C. W. Shults, R. Quirion, T. W. Moody, T. N. Chase, M. Otsuka, S. Konishi, M. Yanagisawa, H. Akagi, U. Otten, U. T. Rüegg, W. Pawlik, S. J. Konturek, J. Kania, P. Gustaw, Patricia G. Cosgrove, Christopher J. Pazoles, J. V. Priestley, R. T. Jensen, C. B. Pert, D. Regoli, J. Mizrahi, P. D'Orléans-Juste, S. Caranikas, E. Escher, Karl Folkers, Urs T. Rüegg, W. R. Bishai, A. Saria, B. V. Rama Sastry, Neelam Jaiswal, Osama S. Tayeb, Hartmut Schultheiss, Joachim Hörig, T. M. Scott, F. Shanahan, A. D. Befus, J. Fox, J. A. Denburg, J. Bienenstock, M. N. Sheppard, S. S. Kurian, R. A. Siegel, J. Weidenfeld, M. Globus, E. Melamed, L. Sjödin, G. Srivastava, Michael E. Hall, A. Suhar, V. Turk, N. Marks, U. Szkudlarek, A. Tarkkanen, T. Tervo, K. Tervo, L. Eränkö, O. Eränkö, W. -M. Huang, J. F. B. Morrison, W. G. Unger, A. Tessler, B. T. Himes, M. Murray, M. E. Goldberger, Y. Torrens, J. C. Beaujouan, A. Viger, J. Glowinski, F. F. Casanueva, E. Knuth, V. Havlicek, H. G. Friesen, J. Triepel, A. Weindl, M. Reinecke, J. Mader, W. G. Forssmann, Thomas Unger, Hans Becker, Manfred König, Detlev Ganten, Rudolf E. Lang, L. L. Vacca, N. E. Naftchi, X. -M. Guan, M. -K. Ai, E. Vijayan, Y. M. Wang, M. L. Mashford, Stephen P. Watson, Bengt E. B. Sandberg, Leslie L. Iversen, E. Weihe, W. Hartschuh, G. Kuchling, E. A. Winter, P. Keen, C. J. Yeo, Jukka Ylikoski, Timo Tervo, Kaarina Tervo, Liisa Eränko, Claudio Cuello

Publikováno v: Irish Journal of Medical Science. 152:11-67

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65539cafef3cc1ae1fa25aafd8b7e4d1
https://doi.org/10.1007/bf02949761

Substance P and neurotensin

Autor: S E, Leeman, N, Aronin, C, Ferris

Publikováno v: Recent progress in hormone research. 38

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6bb70f474e6182be9743284f4439a57a
https://pubmed.ncbi.nlm.nih.gov/6181544

Isolation of human intestinal neurotensin

Autor: R A, Hammer, S E, Leeman, R, Carraway, R H, Williams

Publikováno v: The Journal of biological chemistry. 255(6)

The biologically active peptide neurotensin (NT) has been isolated from fresh postmortem human small intestine and its identity with bovine hypothalamic and intestinal neurotensin has been established. Purification was achieved by gel filtration and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0786ecc3e9a0f584c6d76c8180050ef
https://pubmed.ncbi.nlm.nih.gov/7358684