Výsledky vyhledávání

The quantitative genetic basis of polyandry in the parasitoid wasp, Nasonia vitripennis

Autor: David M. Shuker, A J Phillimore, S E Hodge, Maxwell N. Burton-Chellew, Stuart A. West

Publikováno v: Heredity. 98(2)

Understanding the evolution of female multiple mating (polyandry) is crucial for understanding sexual selection and sexual conflict. Despite this interest, little is known about its genetic basis or whether genetics influences the evolutionary origin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad20316bfbb33826cae0f7c65b0c9923
http://ora.ox.ac.uk/objects/uuid:6c36128f-7709-4071-9fca-81a1fc29d932

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The IDDM13 region containing the insulin-like growth factor binding protein-5 (IGFBP5) gene on chromosome 2q33-q36 and the genetic susceptibility to rheumatoid arthritis

Autor: Pércio S. Gulko, W K Chung, S L Slager, S E Hodge, R J Winchester, T Jackson, L Carleu

Publikováno v: Genes and immunity. 3(2)

We considered that the constitutive over-expression by cultured rheumatoid arthritis (RA) fibroblast-lineage synoviocytes of genes like IGFBP5 could indicate new candidate susceptibility genes. IGFBP5 is located in a region where an insulin-dependent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdb46b07499b573c82e09ad53c0c9b3
https://pubmed.ncbi.nlm.nih.gov/11960310

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Model-free vs. model-based linkage analysis: a false dichotomy?

Autor: S E, Hodge

Publikováno v: American journal of medical genetics. 105(1)

The aim of this article is to dispel some misunderstandings concerning the concepts of model-free or nonparametric linkage analysis (usually meaning affecteds-only analysis) and model-based or parametric analysis (usually meaning classical lod scores

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e9ef6f11f2b9c508af7c6bf283f56ba
https://pubmed.ncbi.nlm.nih.gov/11425002

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Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder

Autor: R, Goedken, E, Ludington, R, Crowe, A J, Fyer, S E, Hodge, J A, Knowles, V J, Vieland, M M, Weissman

Publikováno v: American journal of medical genetics. 96(6)

Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two-point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff306febdf6f6573a1d8865c1533b9cc
https://pubmed.ncbi.nlm.nih.gov/11121181

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Investigation of dopamine receptor (DRD4) and dopamine transporter (DAT) polymorphisms for genetic linkage or association to panic disorder

Autor: S P, Hamilton, F, Haghighi, G A, Heiman, D F, Klein, S E, Hodge, A J, Fyer, M M, Weissman, J A, Knowles

Publikováno v: American journal of medical genetics. 96(3)

Clinical and animal studies suggest a role for the neurotransmitter dopamine in anxiety states. In humans, one such condition is panic disorder, which is typified by recurrent panic attacks accompanied by anticipatory anxiety. Family, segregation, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7abe90b53abcdaa75394d964649146b8
https://pubmed.ncbi.nlm.nih.gov/10898909

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Potential panic disorder syndrome: clinical and genetic linkage evidence

Autor: M M, Weissman, A J, Fyer, F, Haghighi, G, Heiman, Z, Deng, R, Hen, S E, Hodge, J A, Knowles

Publikováno v: American journal of medical genetics. 96(1)

This paper reports evidence for a possible "chromosome 13 syndrome," which includes panic disorder, kidney or bladder problems, serious headaches, thyroid problems (usually hypothyroid), and/or mitral valve prolapse (MVP). In the course of a genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b20906e20966101f73b679d63dddee48
https://pubmed.ncbi.nlm.nih.gov/10686548

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Parent-of-origin effect in panic disorder

Autor: F, Haghighi, A J, Fyer, M M, Weissman, J A, Knowles, S E, Hodge

Publikováno v: American journal of medical genetics. 88(2)

Parent-of-origin effect was examined in a series of 64 pedigrees with panic disorder (PD) under both the narrow and broad diagnostic models. The narrow diagnostic model defined the affected phenotype to include only the "definite" and "probable" form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a80475fac5c34bed3da97fbfe9977036
https://pubmed.ncbi.nlm.nih.gov/10206231

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