Výsledky vyhledávání - "S E, Glickman"

Androgen-independent events in penile development in humans and animals

Autor: Gerald R. Cunha, Mei Cao, Laurence S. Baskin, S. E. Glickman, Adriane Sinclair, Ge Liu, Paul S. Cooke

The common view on penile development is that it is androgen-dependent, based first and foremost on the fact that the genital tubercle forms a penis in males and a clitoris in females. However, critical examination of the complex processes involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba87e0ac860868020241ab8f5d52fa0
https://escholarship.org/uc/item/2hw0b5zp

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Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating

Autor: Elizabeth M. Coscia, Christine M. Drea, Ned J. Place, S. E. Glickman, Paul Licht, Mary L. Weldele

Publikováno v: Proceedings of the Royal Society of London. Series B: Biological Sciences. 269:1981-1987

Among all extant mammals, only the female spotted hyena (Crocuta crocuta) mates and gives birth through the tip of a peniform clitoris. Clitoral morphology is modulated by foetal exposure to endogenous, maternal androgens. First births through this o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a77cc37a7235031db38c2e019f6216
https://doi.org/10.1098/rspb.2002.2109

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Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 3. Effects of juvenile gonadectomy

Autor: Mary L. Weldele, Elizabeth M. Coscia, Paul Licht, Christine M. Drea, Laurence G. Frank, S. E. Glickman

Publikováno v: Reproduction. 113:129-135

Studies involving the administration of anti-androgens to spotted hyaenas during fetal development have raised questions concerning the precise contributions of steroids to phallic growth in these animals. If gonadal androgens promote postnatal penil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340458ee2daa47c9f2bf6b0b3ab4db93
https://doi.org/10.1530/jrf.0.1130129

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Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 1. Urogenital morphology and placental androgen production during fetal life

Autor: G R Cunha, S. E. Glickman, R. B. Jaffe, H. Kim, Paul Licht, M. C. Martin, Pei-San Tsai, M. Golbus, Simon W. Hayward, Tyrone B. Hayes

Publikováno v: Scopus-Elsevier

According to common understanding of sexual differentiation, the formation and development of a penile clitoris in female spotted hyaenas requires the presence of naturally circulating androgens during fetal life. The purpose of the present study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83283f8963426956704fc1a800b7df78
https://doi.org/10.1530/jrf.0.1130105

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Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 2. Effects of prenatal anti-androgens

Autor: Laurence G. Frank, Nancy G. Forger, Christine M. Drea, Elizabeth M. Coscia, Mary L. Weldele, Paul Licht, S. E. Glickman

Publikováno v: Reproduction. 113:117-127

Pregnant spotted hyaenas were treated with anti-androgens to interfere with the unusually masculine 'phallic' development that characterizes females of this species. The effects on genital morphology and plasma androgen concentrations of infants were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec244d65290b5c2ea5d78ebea6f0b15
https://doi.org/10.1530/jrf.0.1130117

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Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

Autor: Sally P. Klemens, Toops Dana S, James O. Kilburn, Susan K. Hendges, Ford Charles W, S. E. Glickman, Gary E. Zurenko, Kevin C. Grega, Steven J. Brickner, Michael H. Cynamon, Hutchinson Douglas K, Barbachyn Michael R

Publikováno v: Journal of Medicinal Chemistry. 39:680-685

During the course of our investigations in the oxazolidinone antibacterial agent area, we have identified a subclass with especially potent in vitro activity against mycobacteria. The salient structural feature of these oxazolidinone analogues, 6 (U-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd36c5010853b90f6315fcfa170f5c2
https://doi.org/10.1021/jm950956y

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Rapid identification of mycolic acid patterns of mycobacteria by high-performance liquid chromatography using pattern recognition software and a Mycobacterium library

Autor: James O. Kilburn, S E Glickman, L S Ramos, W R Butler

Publikováno v: Journal of Clinical Microbiology. 32:740-745

Current methods for identifying mycobacteria by high-performance liquid chromatography (HPLC) require a visual assessment of the generated chromatographic data, which often involves time-consuming hand calculations and the use of flow charts. Our lab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a1b2fed41e6087b5a0fabf2850d89b
https://doi.org/10.1128/jcm.32.3.740-745.1994

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ChemInform Abstract: Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

Autor: Michael H. Cynamon, Steven J. Brickner, Susan K. Hendges, Sally P. Klemens, Hutchinson Douglas K, Gary E. Zurenko, James O. Kilburn, S. E. Glickman, Barbachyn Michael R, Kevin C. Grega, Ford Charles W, Toops Dana S

Publikováno v: ChemInform. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d40bb5e9d59894c74cf379263d5bc877
https://doi.org/10.1002/chin.199621140

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