Zobrazeno 1 - 10
of 68
pro vyhledávání: '"S E, Downing"'
Publikováno v:
Records of the Australian Museum. 47:203-223
From a largely unpublished database the systematics, geographical and stratigraphical distribution of Cainozoic cytherurine Ostracoda found in the deep sea environment of the eastern Indiall and south-western Pacific regions is presented. Eleven new
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:831-840
Oxidative metabolism in reperfused neonatal myocardium has not been characterized. A blood-perfused isovolumic heart preparation was used to quantify metabolic and mechanical responses of the neonatal left ventricle to global normothermic ischemia an
Autor:
S. E. Downing, V. Chen
Publikováno v:
Circulation Research. 66:763-772
We explored the effects of sustained low-flow ischemia on function and metabolism in isolated neonatal hearts. The hearts were extracted from 21 piglets (1-12 days old) and set up as modified Langendorff preparations beating isometrically. They were
Publikováno v:
Acta physiologica Scandinavica. 154(2)
Different conclusions have been reached with regard to the effect of endothelin (ET-1) on cardiac contractility. We examined systolic and diastolic function in response to constant known concentrations of ET-1 with or without ET-1 induced reductions
Publikováno v:
Cardiovascular research. 28(6)
Objective: ATP gated potassium (KATP) channels and adenosine are of crucial importance in coronary blood flow regulation and activation of KATP channels and adenosine receptor stimulation protect against infarction and development of stunning. The ai
Autor:
S. E. Downing
Publikováno v:
The American journal of physiology. 264(2 Pt 2)
Cell viability is maintained during prolonged ischemia (ISCH) in isolated heart systems because mechanical function is nil (acute hibernation). By contrast, a noncontracting ischemic segment in an in vivo heart exhibits irreversible damage after < or
Autor:
V Chen, S E Downing
Publikováno v:
Circulation. 85(2)
BACKGROUND Recovery from prolonged low-flow ischemia was studied in isolated, isovolumically beating neonatal piglet hearts (n = 11) and compared with controls (n = 5). METHODS AND RESULTS Hearts were perfused with red blood cell-enhanced Krebs-Hense
Autor:
J P, Jiang, S E, Downing
Publikováno v:
The Yale Journal of Biology and Medicine
Catecholamines given in high concentrations produce myocardial damage in several mammalian species. The histological changes are similar to those found in patients given large amounts of pressor agents and in those who develop pheochromocytomas. They