Zobrazeno 1 - 10
of 19
pro vyhledávání: '"S E, Barrow"'
Publikováno v:
British Journal of Clinical Pharmacology. 32:127-129
The effect of pravastatin on low density lipoprotein (LDL) cholesterol and platelet activation was studied in 16 patients with mild hypercholesterolaemia who had two or more additional cardiovascular risk factors. Patients were treated with either pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8416d0116f48db65c9a5ad349ea61b4
https://doi.org/10.1111/j.1365-2125.1991.tb05625.x
https://doi.org/10.1111/j.1365-2125.1991.tb05625.x
Publikováno v:
Journal of human hypertension. 10(1)
Protacyclin biosynthesis was investigated in 133 untreated newly diagnosed patients with uncomplicated essential hypertension. Urinary excretion of 6-oxo-prostaglandin F1 alpha and of 2,3-dinor-6-oxo-prostaglandin F1 alpha, stable breakdown products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b02643f5dde79b0b529b37bc320c3ae1
https://pubmed.ncbi.nlm.nih.gov/8642189
https://pubmed.ncbi.nlm.nih.gov/8642189
Publikováno v:
British heart journal. 72(5)
OBJECTIVE--To investigate the effect of intracardiac repair on the abnormal biosynthesis of prostacyclin (PGI2) and thromboxane A2 (TXA2) in children with congenital heart disease and increased pulmonary blood flow. DESIGN--A prospective study with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350a6594a010909c5754842b84377648
https://pubmed.ncbi.nlm.nih.gov/7818962
https://pubmed.ncbi.nlm.nih.gov/7818962
Publikováno v:
Circulation. 88(5 Pt 1)
BACKGROUND The pathogenesis of pulmonary vascular disease in children with congenital heart disease is incompletely understood. Thromboxane (TX) A2 and prostacyclin (PGI2) have opposing effects on platelet aggregation and pulmonary vascular smooth mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70113f93025272556d6b6293b941aeaa
https://pubmed.ncbi.nlm.nih.gov/8222105
https://pubmed.ncbi.nlm.nih.gov/8222105
Autor:
P S, Kontessis, S L, Jones, S E, Barrow, P D, Stratton, P, Alessandrini, S, De Cosmo, J M, Ritter, G C, Viberti
Publikováno v:
The Journal of laboratory and clinical medicine. 121(3)
Studies of nondiabetic renal disease suggest that thromboxane may be an important mediator of abnormal renal function. The role of thromboxane in diabetic nephropathy is not fully understood. We measured in a double-blind, randomized, placebo-control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a21923d59929da962f8fa0a570caf9e5
https://pubmed.ncbi.nlm.nih.gov/8445289
https://pubmed.ncbi.nlm.nih.gov/8445289
Publikováno v:
British heart journal. 69(2)
BACKGROUND--Children with cyanotic congenital heart disease and pulmonary outflow tract obstruction have shortened platelet survival times and are susceptible to thrombosis and organ infarction. Thromboxane A2 and prostacyclin have opposing actions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab82b284b8f87936d77554ab855ddf99
https://pubmed.ncbi.nlm.nih.gov/8435245
https://pubmed.ncbi.nlm.nih.gov/8435245
Publikováno v:
The Journal of biological chemistry. 266(14)
Rainbow trout macrophages maintained in short term culture when incubated with either calcium ionophore, A23187, or opsonized zymosan synthesize a range of lipoxygenase products including lipoxins and leukotrienes. These cells are unusual in that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::714bc051a6340ade8120bd19f75321dd
https://pubmed.ncbi.nlm.nih.gov/1902832
https://pubmed.ncbi.nlm.nih.gov/1902832
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Twenty four healthy men were treated with GR32191, a thromboxane receptor antagonist with a long duration of action, in a double blind placebo-controlled crossover study. Platelet aggregation in response to a thromboxane (TX) mimetic (U46619) was stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91cc34acaa214b0afbb9ec44cdb2550e
https://pubmed.ncbi.nlm.nih.gov/1825568
https://pubmed.ncbi.nlm.nih.gov/1825568
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6158f47dc78ff7eee3d420bf5d17a09c
https://pubmed.ncbi.nlm.nih.gov/1825378
https://pubmed.ncbi.nlm.nih.gov/1825378
Publikováno v:
British journal of clinical pharmacology. 29(4)
1. GR32191B is a potent and selective thromboxane receptor antagonist. Glyceryl trinitrate (GTN) also inhibits platelet function in vitro. Both have been reported to prolong bleeding time. Since they may be used together in patients with coronary art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4ec9f7e896085a6b2dd134775729a8
https://pubmed.ncbi.nlm.nih.gov/2139338
https://pubmed.ncbi.nlm.nih.gov/2139338