Zobrazeno 1 - 10
of 71
pro vyhledávání: '"S Dhut"'
Autor:
Takayoshi Kuno, Takashi Toda, Giulio Superti-Furga, Reiko Sugiura, Eisuke Nishida, S Dhut, Yukiko Gotoh
Publikováno v:
Europe PubMed Central
We have isolated a gene, pmk1+, a third mitogen-activated protein kinase (MAPK) gene homolog from the fission yeast Schizosaccharomyces pombe. The predicted amino acid sequence shows the most homology (63 to 65% identity) to those of budding yeast Sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c8d56e1d1c4b873c9772db2d9e0a41
https://doi.org/10.1128/mcb.16.12.6752
https://doi.org/10.1128/mcb.16.12.6752
Publikováno v:
Blood. 81:2488-2491
We have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q+ as a result of the t(9;22) translocation, is transcriptionally active in 65% of chronic myeloid leukemia patients. We have now used the same technique, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8378bd51465c321ae5a4d94d5ae3fd8
https://doi.org/10.1182/blood.v81.10.2488.bloodjournal81102488
https://doi.org/10.1182/blood.v81.10.2488.bloodjournal81102488
Autor:
I. Goldstein, Philippe Martiat, A. S. Taj, Charles Dowding, Bryan D. Young, JohnM. Goldman, George Q. Daley, T. L. Chaplin, S. Dhut, K. H. Th'ng
Publikováno v:
Leukemia & Lymphoma. 3:201-208
We designed experiments to study the effects on P210BCR/ABL expression of introducing antisense oligonucleotides into K562 cells. We used two antisense oligonucleotides: one (AS1) is complementary to the first coding codon of the BCR/ABL mRNA and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff83173d3b169192636b8bc82e9f902c
https://doi.org/10.3109/10428199009050996
https://doi.org/10.3109/10428199009050996
Autor:
A, Tuszynski, S, Dhut, B D, Young, T A, Lister, A Z, Rohatiner, J A, Amess, T, Chaplin, E, Dorey, B, Gibbons
Publikováno v:
Leukemia. 7(10)
Blast cells from an unselected consecutive series of 84 adults presenting with acute lymphoblastic leukemia (ALL) to St Bartholomew's Hospital over a seven year period were tested prospectively by cytogenetic and retrospectively by RT-PCR analysis fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8381f25ecd96f5a77a680f12bc3d3c2
https://pubmed.ncbi.nlm.nih.gov/8412311
https://pubmed.ncbi.nlm.nih.gov/8412311
Publikováno v:
Blood. 81(10)
We have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q+ as a result of the t(9;22) translocation, is transcriptionally active in 65% of chronic myeloid leukemia patients. We have now used the same technique, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a53198b9dba9d7ada100b532c5937b75
https://pubmed.ncbi.nlm.nih.gov/8490164
https://pubmed.ncbi.nlm.nih.gov/8490164
Publikováno v:
Oncogene. 6(8)
The subcellular distribution of the c-abl and bcr-abl gene products from KG1A and K562 cells has been studied by two different techniques. Firstly, physical disruption followed by subcellular fractionation was used to demonstrate that normal c-abl (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7a1ca87e63d83f8ef646e7f7208ab2e
https://pubmed.ncbi.nlm.nih.gov/1886716
https://pubmed.ncbi.nlm.nih.gov/1886716
Publikováno v:
Genes, chromosomescancer. 3(1)
The t(4;11)(q21;q23) has been associated with acute lymphocytic leukemia (ALL) especially in infants. The t(4;11) breakpoint on chromosome 11 is cytogenetically indistinguishable from breakpoints for other leukemia-associated translocations affecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::621a1f63bec1c39570832f3f820c1abc
https://pubmed.ncbi.nlm.nih.gov/1829960
https://pubmed.ncbi.nlm.nih.gov/1829960
Publikováno v:
Leukemia. 5(1)
A lymphoblastoid cell line (SD-1) has been established by Epstein-Barr virus immortalisation of Philadelphia chromosome positive acute lymphoblastic leukaemia (ALL) cells. Using newly derived anti-bcr monoclonal and anti-abl polyclonal antibodies it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb48ceff33aa7247a6ca046fb06f443a
https://pubmed.ncbi.nlm.nih.gov/1847983
https://pubmed.ncbi.nlm.nih.gov/1847983
Publikováno v:
Leukemia. 4(11)
The Philadelphia translocation results in the expression of a family of chimaeric proteins in which a portion of the bcr protein is fused to c-abl protein. Using antibodies which recognize different portions of the bcr gene and abl gene products we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4255b4330efaa8020fe574ef2999b0d
https://pubmed.ncbi.nlm.nih.gov/2232885
https://pubmed.ncbi.nlm.nih.gov/2232885
Publikováno v:
Clinical and experimental immunology. 59(2)
Monoclonal antibodies were raised against a laboratory derived variant of the Raji Burkitt lymphoma cell line. We have characterized two of these antibodies by screening on haematopoietic cell lines, and frozen sections of both reactive and neoplasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc8f0afafc475cd72efc12289896f7ab
https://pubmed.ncbi.nlm.nih.gov/3872187
https://pubmed.ncbi.nlm.nih.gov/3872187