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pro vyhledávání: '"S D, Shumway"'
Autor:
T T, Huang, S M, Wuerzberger-Davis, B J, Seufzer, S D, Shumway, T, Kurama, D A, Boothman, S, Miyamoto
Publikováno v:
The Journal of biological chemistry. 275(13)
Activation of the transcription factor NF-kappaB by extracellular signals involves its release from the inhibitor protein IkappaBalpha in the cytoplasm and subsequent nuclear translocation. NF-kappaB can also be activated by the anticancer agent camp
Publikováno v:
The Journal of biological chemistry. 274(43)
Polypeptide sequences enriched in proline (P), glutamate (E), serine (S), and threonine (T), dubbed PEST domains, are proposed to expedite the degradation of proteins. The proteolysis of one PEST-containing protein, IkappaBalpha, is prerequisite to t