Výsledky vyhledávání

Signal antonymy unique to myelodysplastic marrows correlates with altered expression of E2F1

Autor: S D, Mundle, B Y, Mativi, J D, Cartlidge, B, Dangerfield, L, Broady-Robinson, B, Li, V, Shetty, P, Venugopal, S A, Gregory, H D, Preisler, A, Raza

Publikováno v: British journal of haematology. 109(2)

Myelodysplastic syndromes (MDS) have previously been reported to show competitively high rates of apoptosis and proliferation in the bone marrow (BM). Using a double-labelling technique in the present study, we demonstrated that a significantly high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10e23039504974b5e7904d2dcca50163
https://pubmed.ncbi.nlm.nih.gov/10848828

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Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows

Autor: S D, Mundle, B Y, Mativi, K, Bagai, G, Feldman, P, Cheema, U, Gautam, S, Reza, J D, Cartlidge, P, Venugopal, V, Shetty, S A, Gregory, E, Robin, S, Rifkin, R, Shah, A, Raza

Publikováno v: International journal of hematology. 70(2)

In this study, we examined the role of Fas-signaling in the apoptotic pathway in myelodysplastic syndromes (MDS). Ficoll-separated mononuclear cells from 18 bone marrow aspirate specimens obtained from 17 MDS patients, 4 normal healthy donors, and 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9439c74940bf4920fa7969c026cd026b
https://pubmed.ncbi.nlm.nih.gov/10497846

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Evidence for involvement of tumor necrosis factor-alpha in apoptotic death of bone marrow cells in myelodysplastic syndromes

Autor: S D, Mundle, A, Ali, J D, Cartlidge, S, Reza, S, Alvi, M M, Showel, B Y, Mativi, V T, Shetty, P, Venugopal, S A, Gregory, A, Raza

Publikováno v: American journal of hematology. 60(1)

We previously reported excessive apoptosis and high levels of tumor necrosis factor-alpha (TNF-alpha) in the bone marrows of patients with myelodysplastic syndromes (MDS), using histochemical techniques. The present studies provide further circumstan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8921a7ddb048c395b3c20f446f1722ce
https://pubmed.ncbi.nlm.nih.gov/9883804

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Indication of an involvement of interleukin-1 beta converting enzyme-like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes

Autor: S D, Mundle, P, Venugopal, J D, Cartlidge, D V, Pandav, L, Broady-Robinson, S, Gezer, E L, Robin, S R, Rifkin, M, Klein, D E, Alston, B M, Hernandez, D, Rosi, S, Alvi, V T, Shetty, S A, Gregory, A, Raza

Publikováno v: Blood. 88(7)

Our previous studies using in situ end labeling (ISEL) of fragmented DNA revealed extensive apoptotic cell death in the bone marrows (BM) of patients with myelodysplastic syndromes (MDS) involving both stromal and hematopoietic cells. In the present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::887154a8c162de95e6f03d8e1da1f5cd
https://pubmed.ncbi.nlm.nih.gov/8839858

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Two in situ labeling techniques reveal different patterns of DNA fragmentation during spontaneous apoptosis in vivo and induced apoptosis in vitro

Autor: S D, Mundle, X Z, Gao, S, Khan, S A, Gregory, H D, Preisler, A, Raza

Publikováno v: Anticancer research. 15(5B)

Two new enzymatic reactions were described recently to detect apoptotic cell death in situ viz in situ end labeling (ISEL) and terminal deoxynucleotidyl transferase mediated UTP nick end labeling (TUNEL) of fragmented DNA. A comparative study was con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9bb0b0014dd4ec3e05c8c623067046e
https://pubmed.ncbi.nlm.nih.gov/8572575

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Dual regulatory action of prostatic inhibin (10.7 kDa) on DNA synthesis

Autor: N A, Sheth, T R, Teni, S D, Mundle

Publikováno v: Indian journal of experimental biology. 30(11)

Present studies deal with the role of inhibin in proliferation and growth. The effect of inhibin on incorporation of 3H-thymidine in prostatic DNA in vivo as well as by NRK-49F and Balb/c3T3 cell lines in vitro, was investigated. Also studied the imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7898e41a4f2d04c121badb11f3ef035
https://pubmed.ncbi.nlm.nih.gov/1293025

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Inhibition of PHA-stimulated proliferation of peripheral blood mononuclear cells by human seminal plasma inhibin (HSPI)

Autor: S D, Mundle, T R, Teni, N A, Sheth

Publikováno v: Journal of clinicallaboratory immunology. 38(4)

This report deals with the effect of purified HSPI (10.7 kDa single chain prostatic peptide of 94 amino acids) on PHA-stimulated proliferation of peripheral blood mononuclear cells (PBMNC). HSPI was found to inhibit the incorporation of 3H-thymidine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba2c31cfaa3695b0dcaec672fcc53d91
https://pubmed.ncbi.nlm.nih.gov/11270519

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In vivo suppression of pituitary and circulatory follicle stimulating hormone by human seminal plasma inhibin

Autor: S D, Mundle, N A, Sheth

Publikováno v: Indian journal of experimental biology. 29(4)

Human seminal plasma inhibin (HSPI), of prostatic origin, has been shown to bring about a dose dependent suppression in pituitary and circulatory FSH concentrations in intact rats. No significant changes in LH levels either in pituitary or in circula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b060ee6281bd0b1b4b44d0556b0b6c29
https://pubmed.ncbi.nlm.nih.gov/1908437

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