Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S D, Lyons"'
Publikováno v:
Climacteric : the journal of the International Menopause Society. 23(4)
Endometrial polyps are a common finding, with a prevalence of about 40%, and are usually diagnosed incidentally as most are asymptomatic. Symptomatic polyps usually present with abnormal uterine bleeding and/or sub-fertility. About 25% of polyps reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ec81a8f19faebf97c9f3b9a5af4f7d
https://pubmed.ncbi.nlm.nih.gov/32496825
https://pubmed.ncbi.nlm.nih.gov/32496825
Publikováno v:
The Journal of biological chemistry. 267(16)
The pathway for de novo biosynthesis of purine nucleotides contains two one-carbon transfer reactions catalyzed by glycinamide ribotide (GAR) and 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylases in which N10-formyltetrahydrofolate is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::739a5e7f8db13754d4eaea1683bb3c8e
https://pubmed.ncbi.nlm.nih.gov/1597445
https://pubmed.ncbi.nlm.nih.gov/1597445
Autor:
S D, Lyons, R I, Christopherson
Publikováno v:
Biochemistry international. 24(1)
Polyglutamated dihydrofolate, accumulated as a result of potent inhibition of dihydrofolate reductase (DHFR), has been postulated to directly inhibit the purine pathway at 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase (reaction 9) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc6bff28965b48f6140a8c098d3f3f7c
https://pubmed.ncbi.nlm.nih.gov/1768258
https://pubmed.ncbi.nlm.nih.gov/1768258
Autor:
J, Brooke, E, Szabados, S D, Lyons, R J, Goodridge, M C, Harsanyi, A, Poiner, R I, Christopherson
Publikováno v:
Cancer research. 50(24)
6-L-Thiodihydroorotate (TDHO) and 2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylate (HDDP) are potent inhibitors of mammalian dihydroorotase in vitro (R. I. Christopherson, K. J. Schmalzl, E. Szabados, R. J. Goodridge, M. C. Harsanyi, M. E. Sant,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c34a3d6a55dd64f665c953f95d4ad69c
https://pubmed.ncbi.nlm.nih.gov/1979249
https://pubmed.ncbi.nlm.nih.gov/1979249
Autor:
S D, Lyons, R I, Christopherson
Publikováno v:
Biochemistry international. 22(6)
Exposure of mouse L1210 leukemia cells to 25 microM brequinar for 4 h results in large accumulations of N-carbamyl-L-aspartate and L-dihydroorotate to cellular concentrations of 8.5 mM and 0.8 mM, respectively, while UTP and CTP decrease to 4% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70700f39aa0dd83a649e51d91c63f651
https://pubmed.ncbi.nlm.nih.gov/1965281
https://pubmed.ncbi.nlm.nih.gov/1965281
Publikováno v:
The Journal of biological chemistry. 265(19)
The glutamine antagonists, acivicin (NSC 163501), azaserine (NSC 742), and 6-diazo-5-oxo-L-norleucine (DON) (NSC 7365), are potent inhibitors of many glutamine-dependent amidotransferases in vitro. Experiments performed with mouse L1210 leukemia grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6867e7a16ca1c7367b5303ce1ef7c247
https://pubmed.ncbi.nlm.nih.gov/2358467
https://pubmed.ncbi.nlm.nih.gov/2358467
Publikováno v:
The Journal of biological chemistry. 261(32)
Acivicin (NSC 163501) and dichloroallyl lawsone (NSC 126771) are potent inhibitors of nucleotide biosynthesis with consequent anti-cancer activity against certain experimental tumors. To determine in detail the metabolic events induced by each inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b8e4061b23fefb31573dcec6f2b9d1d
https://pubmed.ncbi.nlm.nih.gov/3771555
https://pubmed.ncbi.nlm.nih.gov/3771555
Publikováno v:
The American surgeon. 54(2)
This preliminary report suggests superior efficacy of a mixture of Sodium Tetradecyl Sulfate, thrombin and cefazolin (ST-Thr-Cef) over 1% Sodium Tetradecyl Sulfate (ST) in the early control of variceal bleeding. The overall management of patients tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73b741d76e80832a7bcf85d85933131f
https://pubmed.ncbi.nlm.nih.gov/3257666
https://pubmed.ncbi.nlm.nih.gov/3257666
Publikováno v:
Cancer research. 49(10)
Pyrazofurin (NSC 143095) as the monophosphate derivative is a potent inhibitor of orotidine 5'-monophosphate (OMP) decarboxylase of the pyrimidine pathway and has been proposed to inhibit 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f0f692863b7fd266d66652e67be67d8
https://pubmed.ncbi.nlm.nih.gov/2713848
https://pubmed.ncbi.nlm.nih.gov/2713848