Zobrazeno 1 - 10
of 14
pro vyhledávání: '"S D, Leach"'
Autor:
S. Dhara, S. Chhangawala, H. Chintalapudi, G. Askan, V. Aveson, A. L. Massa, L. Zhang, D. Torres, A. P. Makohon-Moore, N. Lecomte, J. P. Melchor, J. Bermeo, A. Cardenas, S. Sinha, D. Glassman, R. Nicolle, R. Moffitt, K. H. Yu, S. Leppanen, S. Laderman, B. Curry, J. Gui, V. P. Balachandran, C. Iacobuzio-Donahue, R. Chandwani, C. S. Leslie, S. D. Leach
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prog
Externí odkaz:
https://doaj.org/article/6977d7f3af4b4cfabd67f3e6911c6b38
Autor:
S. D. Leach, Edward D. Houde
Publikováno v:
Journal of Fish Biology. 54:767-786
Episodic increases in temperature of 5°C above 20° C, over 48 h or declines in pH of 1·0 unit from pH 7·0 reduced survival of yolk-sac and feeding-stage larvae of American shad Alosa sapidissima . Over 16 days all measures of survival, growth, an
Publikováno v:
Cancer journal (Sudbury, Mass.). 7(4)
The specific cell of origin responsible for generating pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma remains unknown. During development, epithelial stem cells within embryonic pancreatic epithelium give riseto mature acin
Autor:
D, Delbeke, D M, Rose, W C, Chapman, C W, Pinson, J K, Wright, R D, Beauchamp, Y, Shyr, S D, Leach
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(11)
This study had two purposes: to optimize the semiquantitative interpretation of 18F-fluorodeoxyglucose (FDG) PET scans in the diagnosis of pancreatic carcinoma by analyzing different cutoff levels for the standardized uptake value (SUV), with and wit
Autor:
A M, Lowy, S D, Leach
Publikováno v:
Oncology (Williston Park, N.Y.). 13(10 Suppl 5)
Both gastric and pancreatic cancer remain leading causes of cancer death in the United States and worldwide. While surgical resection continues to be required for long-term cure of both these neoplasms, 5-year survival rates remain poor following sur
Publikováno v:
Cancer treatment and research. 98
Publikováno v:
Ecosystems at the Land-Sea Margin: Drainage Basin to Coastal Sea
Fisheries of the Chesapeake bay and Northern Adriatic sea are reveiwed and compared with respect to constituents of the catch, trends, and management issues. In both systems , prospects for continued high fisheries productivity depend upon effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d150aee80e7f55672412258afd79321
https://doi.org/10.1029/ce055p0341
https://doi.org/10.1029/ce055p0341
Publikováno v:
Cancer research. 58(15)
The G2 cell cycle checkpoint protects cells from potentially lethal mitotic entry after DNA damage. This checkpoint involves inhibitory phosphorylation of Cdc2 at the tyrosine-15 (Y15) position, mediated in part by the Wee1 protein kinase. Recent evi
Publikováno v:
Anticancer research. 17(2A)
Because treatment of advanced pancreatic cancer is often unsuccessful, early detection is important. Codon 12 c-Ki-ras mutations have been found in 80-90% of pancreatic cancer cases and are a potential early marker for pancreatic cancer, but obtainin
bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: association with clinical outcome
Autor:
F A, Sinicrope, D B, Evans, S D, Leach, K R, Cleary, C J, Fenoglio, J J, Lee, J L, Abbruzzese
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(12)
The bcl-2 proto-oncogene and the p53 tumor suppressor gene are important determinants of tumor cell susceptibility to apoptosis. bcl-2 and mutant p53 proteins inhibit apoptosis in vitro and can provide prognostic information in certain tumor types. W