Zobrazeno 1 - 10
of 43
pro vyhledávání: '"S D, Hall"'
Autor:
S D. Hall, Michael F. Murphy, Charles Craddock, Robert Danby, Vanderson Rocha, H. Osman, Andy Peniket, S. Chaganti
Publikováno v:
Transfusion Medicine. 25:418-423
SUMMARY Objectives To establish rates of cytomegalovirus (CMV) transmission with use of CMV-unselected (CMV-U), leukocyte-reduced blood components transfused to CMV-seronegative patient/CMV-seronegative donor (CMV neg/neg) allogeneic stem cell transp
Autor:
Y, Jin, Y-H, Wang, J, Miao, L, Li, R J, Kovacs, R, Marunde, M A, Hamman, S, Philips, S, Phillips, J, Hilligoss, S D, Hall
Publikováno v:
Clinical Pharmacology & Therapeutics. 82:579-585
We hypothesized that CYP3A5 genotype contributes to the interindividual variability in verapamil response. Healthy subjects (n=26) with predetermined CYP3A5 genotypes were categorized as expressers (at least one CYP3A5(*)1 allele) and nonexpressers (
Publikováno v:
Experiments in Fluids. 35:139-151
An experimental study of a turbulent backward-facing step (BFS) was undertaken to investigate the vortex structures behind the step. Attention was given to the secondary vortex because of its poor representation in literature and its potential for ev
Autor:
M. P. Knadler, S. D. Hall
Publikováno v:
Chirality. 2:67-73
The inversion from R- to S-enantiomer that occurs for some arylpropionic acids may have both toxicological and therapeutic implications. To characterize some properties of this inversion, arylpropionyl-CoA thioester formation was studied in rat tissu
Publikováno v:
Clinical pharmacology and therapeutics. 70(4)
St John's wort (Hypericum perforatum) is a popular over-the-counter dietary supplement and herbal remedy that has been implicated in drug interactions with substrates of several cytochrome P450 (CYP) isozymes. The effect of St John's wort on CYP acti
Publikováno v:
Oral microbiology and immunology. 15(2)
To ascertain whether epithelial cells of oral cavity origin may be infected with human immunodeficiency virus (HIV-1), a study to determine susceptibility to infection of salivary gland epithelial cell lines (HSY and HSG) was undertaken. Because of t
Publikováno v:
Biochemical pharmacology. 60(1)
The stereoselective sulfoxidation of the pharmacologically active metabolite of sulindac, sulindac sulfide, was characterized in human liver, kidney, and cDNA-expressed enzymes. Kinetic parameter estimates (pH = 7.4) for sulindac sulfoxide formation
Publikováno v:
British journal of clinical pharmacology. 48(4)
To assess if futile cycling of ketoprofen occurs in patients with decreased renal function.Ketoprofen was administered to six haemodialysis-dependent patients with end-stage renal disease as single (50 mg) or multiple doses (50 mg three times daily,
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(3)
Diltiazem (DTZ) N-demethylation occurs by cytochrome P-450 (CYP) 3A based on the following observations: 1) a single enzyme Michaelis-Menten model of metabolite formation, 2) high correlations of DTZ N-demethylation activity to other CYP3A activities
Publikováno v:
Pharmacogenetics. 8(2)
The effect of ionic strength, assay constituents, alpha-naphthoflavone (aNF), terfenadine and testosterone on human CYP3A mediated midazolam (MDZ) 1'-hydroxylation (MDZ 1'-OH) and 4-hydroxylation (MDZ 4-OH) in vitro was examined. Increasing concentra