Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S D, Gorman"'
Autor:
S, Fournel, C, Vincent, O, Assossou, S D, Gorman, E, Robinet, J M, Phillips, M, Flacher, G, Cordier, H, Waldmann, J P, Revillard
Publikováno v:
Transplantation. 62(8)
Knowing that several CD4 mAbs may delay allograft rejection in the absence of circulating CD4+ lymphocyte depletion in vivo, we investigated the mechanisms whereby CD4 mAbs can interfere with the development of alloreactive T cells in the mixed lymph
Publikováno v:
Therapeutic immunology. 1(5)
Antibody-mediated lysis of cells involves a complex interaction between the cell, the target antigen, the antibody and host effector mechanisms. One such mechanism, complement-mediated cell lysis, requires the interaction of C1q with the antibody hea
Autor:
S D, Gorman, M R, Clark
Publikováno v:
Seminars in immunology. 2(6)
Monoclonal antibodies are playing an increasing role in many experimental therapies. A major limitation of their use is that they are recognised by the patient as being of foreign origin and an antiglobulin response is provoked. Recombinant DNA techn
Publikováno v:
The Journal of Immunology. 140:3646-3653
We have isolated the Ly-3 gene by chromosomal walking from the previously cloned Ly-2 gene. These genes are shown to be 36 kb apart and in the same transcriptional orientation. Transfection of the Ly-3 gene into mouse L cells results in cell surface
Publikováno v:
The Journal of Experimental Medicine
Human CD8 has been thought to consist of disulfide-linked homodimers and homomultimers of a single polypeptide chain homologous to mouse and rat CD8 alpha. In contrast, mouse and rat CD8 are composed of disulfide-linked heterodimers of alpha and beta
Autor:
S D, Gorman, V J, Cristofalo
Publikováno v:
Experimental cell research. 167(1)
Senescence of the human diploid fibroblast-like cell line, WI38, is characterized by a loss of proliferative activity and an arrest of cells with a 2C DNA content (G1 or G0). To examine the specific region within G1 in which senescent cells arrest, s