Výsledky vyhledávání

Transverse aortic constriction induces gut barrier alterations, microbiota remodeling and systemic inflammation

Autor: Lorena Coretti, Mariella Cuomo, Orlando Paciello, S D'Apice, Francesca Lembo, Giuseppina Mattace Raso, Roberta Paolillo, Gina Cavaliere, Cinzia Perrino, Ilaria d'Aquino, Maria Pina Mollica, Giuseppe Giugliano, Gabriele G. Schiattarella, Giovanni Esposito, Adriano Lama, Nicola Boccella

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports

Accumulating evidence suggests that modifications of gut function and microbiota composition might play a pivotal role in the pathophysiology of several cardiovascular diseases, including heart failure (HF). In this study we systematically analysed g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3620952ad60da81fbc04b853cd1b1e1a
https://doaj.org/article/c74fa22f500346549147bf13cc6d2327

Zobrazit plný text záznamu

Plný text ve formátu HTML

Small nucleolar RNA SNORD3A: a potential new biomarker and molecular player in heart failure

Autor: C L Holley, Cinzia Perrino, A. Della Corte, Gabriele G. Schiattarella, S D'Apice, Roberta Paolillo, Giovanni Esposito, Ciro Bancone

Publikováno v: European Heart Journal. 42

Background Despite optimal therapy, heart failure (HF) remains a relentless and deadly disease. Given the relative inaccessibility of myocardial human tissues, identification of circulating biomarkers mirroring myocardial pathological signaling pathw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23ceecf54fc797b2363f655f9f1ef63f
https://doi.org/10.1093/eurheartj/ehab724.3281

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Transverse aortic constriction impairs intestinal barrier integrity, promotes inflammation and alterations in gut microbiota composition

Autor: G. Mattace Raso, Adriano Lama, Giovanni Esposito, Cinzia Perrino, S D'Apice, Lorena Coretti, Francesca Lembo, Maria Pina Mollica, Gabriele G. Schiattarella, Roberta Paolillo, Nicola Boccella

Publikováno v: European Heart Journal. 41

Background Microbiota composition plays an important role in the pathophysiology of heart failure (HF). Reduced cardiac output can disrupt intestinal barrier function and promote systemic inflammation through bacterial translocation. Several gut and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::056b8705330854379ba1b3d40768e129
https://doi.org/10.1093/ehjci/ehaa946.3667

Zobrazit plný text záznamu

Aging-associated cardiac dysfunction and leaky gut in heterozygous Akap1 knockout mice

Autor: Francesca Lembo, Cinzia Perrino, Lorena Coretti, M Avvediemnto, Maria Pina Mollica, Adriano Lama, Roberta Paolillo, S D'Apice, G. Mattace Raso, Giovanni Esposito, Nicola Boccella

Publikováno v: European Heart Journal. 41

Background Mitochondrial A-kinase anchoring proteins (mitoAKAPs) encoded by the Akap1 gene are crucially involved in multiple cellular processes, including cardiomyocyte survival and function. There is a correlation between ROS production, intestinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33a8283f31c4c0d603ba7f416b0108fc
https://doi.org/10.1093/ehjci/ehaa946.3605

Zobrazit plný text záznamu