Structural and Spectroscopic Study of New Copper(II) and Zinc(II) Complexes of Coumarin Oxyacetate Ligands and Determination of Their Antimicrobial Activity

Autor: Muhammad Mujahid, Natasha Trendafilova, Georgina Rosair, Kevin Kavanagh, Maureen Walsh, Bernadette S. Creaven, Ivelina Georgieva

Publikováno v: Molecules, Vol 28, Iss 11, p 4560 (2023)

Tackling antimicrobial resistance is of increasing concern in a post-pandemic world where overuse of antibiotics has increased the threat of another pandemic caused by antimicrobial-resistant pathogens. Derivatives of coumarins, a naturally occurring

Externí odkaz: https://doaj.org/article/4a1720aad2f541c9bb0809b4b3bb5dd7

Novel Coumarin-Thiadiazole Hybrids and Their Cu(II) and Zn(II) Complexes as Potential Antimicrobial Agents and Acetylcholinesterase Inhibitors

Autor: Karolina Starzak, Hollie Jenkins, Anna Miłoś, Daniel Kamiński, Lidia Ślusarczyk, Arkadiusz Matwijczuk, Katarzyna Lecka-Szlachta, Piotr Radomski, Dariusz Karcz, Bernadette S. Creaven, Ewa Ciszkowicz

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9709, p 9709 (2021)
Articles

A series of coumarin-thiadiazole hybrids and their corresponding Cu(II) and Zn(II) complexes were synthesized and characterized with the use of spectroscopic techniques. The results obtained indicate that all the coumarin-thiadiazole hybrids act as b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d52613a6fed768db80209df653a9b52

Anti-Hypochlorite, Antioxidant, and Catalytic Activity of Three Polyphenol-Rich Super-Foods Investigated with the Use of Coumarin-Based Sensors

Autor: Janusz Podleśny, Tomasz Świergosz, Bernadette S. Creaven, Arkadiusz Matwijczuk, Dariusz Karcz, Karolina Starzak

Publikováno v: Biomolecules, Vol 10, Iss 723, p 723 (2020)
Biomolecules
Volume 10
Issue 5
Articles

The anti-hypochlorite activity of aç
aí
(Euterpe oleracea Mart.), goji (Lycium barbarum L.) and schisandra (Schisandra chinensis) fruit extracts were assessed by determining the reactive chlorine species (RCS)-scavenging ability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944bc5cef3f940a618dd17564420f206
https://www.mdpi.com/2218-273X/10/5/723

Fluorescence Quenching-Based Mechanism for Determination of Hypochlorite by Coumarin-Derived Sensors

Autor: Arkadiusz Matwijczuk, Bernadette S. Creaven, Sławomir Wybraniec, Dariusz Karcz, Karolina Starzak, Alicja Matwijczuk

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 2
Articles
International Journal of Molecular Sciences, Vol 20, Iss 2, p 281 (2019)

A fluorescence quenching-based mechanism for the determination of hypochlorite was proposed based on spectroscopic and chromatographic studies on the hypochlorite-sensing potency of three structurally similar and highly fluorescent coumarins. The mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35deda38e4406c80eec9f521f0c43f92

Interaction of anticancer reduced Schiff base coumarin derivatives with human serum albumin investigated by fluorescence quenching and molecular modeling

Autor: Éva A. Enyedy, Darius Karcz, Maureen Walsh, Orsolya Dömötör, Tiziano Tuccinardi, Bernadette S. Creaven

Publikováno v: Bioorganic Chemistry. 52:16-23

The specific binding of five reduced Schiff base derived 7-amino-coumarin compounds with antitumor activity to human serum albumin, the principal binding protein of blood, was studied by fluorescence spectroscopy. Their conditional binding constants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc26eff63f895ef0a92e369783b0c5a
https://doi.org/10.1016/j.bioorg.2013.10.003