Results of the c-TRAK TN trial: a clinical trial utilising ctDNA mutation tracking to detect molecular residual disease and trigger intervention in patients with moderate and high-risk early stage triple negative breast cancer

Autor: N.C. Turner, C. Swift, B. Jenkins, L. Kilburn, M. Coakley, M. Beaney, L. Fox, K. Goddard, I. Garcia-Murillas, P. Proszek, P. Hall, C. Harper-Wynne, T. Hickish, S. Kernaghan, I.R. Macpherson, A.F.C. Okines, C. Palmieri, S. Perry, K. Randle, C. Snowdon, H. Stobart, A.M. Wardley, D. Wheatley, S. Waters, M.C. Winter, M. Hubank, S.D. Allen, J.M. Bliss, null S. Chan, A. Armstrong, F. Raja, P. Schmid, A. Tutt, R. Roux, S. Cleator

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology.

Post-treatment detection of circulating tumour DNA (ctDNA) in early-stage triple negative breast cancer (TNBC) patients predicts high risk of relapse. c-TRAK-TN assessed the utility of prospective ctDNA surveillance in TNBC and the activity of pembro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d238819f29088a42d7123a88399a2b
https://pubmed.ncbi.nlm.nih.gov/36423745

96P The Hammersmith score optimises patient selection and predicts for overall survival in early-phase cancer trial participants independent of tumour burden

Autor: J.A. Korolewicz, B. Scheiner, C. Fulgenzi, A. D'Alessio, A. Cortellini, C. Pascual, A. Mehan, S.E. Partridge, O. Mohammed, A. Gupta, L. Booker, S. Cleator, J. Rackie, Y. Needham, J. Krell, L. Tookman, W-H.E. Park, M. Asif, J. Evans, D.J. Pinato

Publikováno v: ESMO Open. 8:100954

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cdc55ad7b243494d3cd81bc293d0e5c
https://doi.org/10.1016/j.esmoop.2023.100954

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Quality of life after postmastectomy radiotherapy in patients with intermediate-risk breast cancer (SUPREMO): 2-year follow-up results of a randomised controlled trial

Autor: Galina Velikova, Linda Jane Williams, Sarah Willis, J Michael Dixon, Juliette Loncaster, Matthew Hatton, Jacqueline Clarke, Ian H Kunkler, Nicola S Russell, A Alhasso, D Adamson, H Algurafi, R Allerton, C Anandadas, A Bahl, L Barraclough, P Barrett-Lee, U Barthakur, C Bedi, M Beresford, J Bishop, G Blackman, P Bliss, D Bloomfield, M Blunt, T Branson, L Brazil, A Brunt, A Chakrabarti, A Chittalie, M Churn, J Clarke, S Cleator, P Crellin, F Danwata, S De-Silva-Minor, A Dhadda, A Eicholz, I Fernando, J Forrest, J Fraser, K Geropantas, A Goodman, R Grieve, M Griffin, M Hadaki, A Hall, M Hatton, J Hicks, S Hignett, M Hogg, R Jyothirmayi, M Khan, S Kumar, P Lawton, D Lee, C Lewinski, C Lim, I Locke, J Loncaster, G Lumsden, S Lupton, B Magee, J Marshall, S Masinghe, C McGregor, M McLennan, P Memtsa, D Milanovic, V Misra, N Mithal, MB Mukesh, A Neal, S Needleman, M Persic, M Quigley, S Raj, P Riddle, D Ritchie, F Roberts, P Robson, H Roe, M Rolles, N Shah, R Sharma, E Sherwin, P Simmonds, G Skailles, S Skaria, W Soe, R Sripadam, A Stevens, A Stockdale, N Storey, I Syndikus, N Thorp, S Upadhyay, M Varughese, N Walji, R Welch, T Wells, V Wolstenholme, P Woodings, F Yuille

Publikováno v: Velikova, G, Williams, L J, Willis, S, Dixon, J M, Loncaster, J, Hatton, M, Clarke, J & Kunkler, I H & Russell, N S 2018, ' Quality of life after postmastectomy radiotherapy in patients with intermediate-risk breast cancer (SUPREMO): 2-year follow-up results of a randomised controlled trial ', The Lancet Oncology, vol. 19, no. 11, pp. 1516-1529 . https://doi.org/10.1016/S1470-2045(18)30515-1

Background\ud Postmastectomy radiotherapy in patients with four or more positive axillary nodes reduces breast cancer mortality, but its role in patients with one to three involved nodes is controversial. We assessed the effects of postmastectomy rad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7eefbeb3155fb3d0fff68395c27216
https://hdl.handle.net/20.500.11820/d9fb43b0-f195-426b-9cad-a09a048fb401

OC-0595: FAST-Forward phase 3 RCT of 1-week hypofractionated breast radiotherapy:3-year normal tissue effects

Autor: A.M. Brunt, Rada Zotova, Duncan Wheatley, Anna M. Kirby, Joanne S Haviland, C. Chan, M. Wilcox, Cliona C. Kirwan, Adrian Harnett, Abdulla Alhasso, E. Sawyer, John Yarnold, Navita Somaiah, Andrew Goodman, C. Morris, Penelope Hopwood, Judith M Bliss, S. Cleator, M. Sydenham, Clare Griffin, Mark Churn, D. Bloomfield, C. Coles, M. Emson, Isabel Syndikus

Publikováno v: Radiotherapy and Oncology. 127:S311-S312

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a493f4e6d329ffe793dcb0adefb1dbc5
https://doi.org/10.1016/s0167-8140(18)30905-8