Výsledky vyhledávání - "S C W Chalcroft"

Grapefruit juice has no effect on quinine pharmacokinetics

Autor: Peter F. Coville, Sompon Wanwimolruk, S. C. W. Chalcroft, Ping-Chuen Ho

Publikováno v: European Journal of Clinical Pharmacology. 55:393-398

Objective: As quinine is mainly metabolised by human liver CYP3A4 and grapefruit juice inhibits CYP3A4, the effect of grapefruit juice on the pharmacokinetics of quinine following a single oral dose of 600 mg quinine sulphate was investigated. Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59b557ff7c28a7dd57d2e30a81d9eb4
https://doi.org/10.1007/s002280050646

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Genetic polymorphism of debrisoquine (CYP2D6) and proguanil (CYP2C19) in South Pacific Polynesian populations

Autor: Peter F. Coville, S. C. W. Chalcroft, S. Bhawan, Sompon Wanwimolruk

Publikováno v: European journal of clinical pharmacology. 54(5)

Genetic oxidation polymorphisms of debrisoquine (CYP2D6) and proguanil (CYP2C19) were studied in unrelated healthy South Pacific Polynesian volunteers recruited in the South Island of New Zealand.Phenotyping for CYP2D6 and CYP2C19 activities was dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a85145c4b767b6297ff53df633365eb
https://pubmed.ncbi.nlm.nih.gov/9754989

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Evidence for the polymorphic oxidation of debrisoquine and proguanil in a New Zealand Maori population

Autor: J.R. Denton, P A Barron, J.R. Broughton, S C W Chalcroft, Sompon Wanwimolruk, E L Pratt

Publikováno v: Pharmacogenetics. 5(4)

The genetic oxidation polymorphisms of debrisoquine and proguanil were studied in a New Zealand Maori population. A bimodal distribution was observed in the 0-4 h urinary debrisoquine/4-hydroxydebrisoquine metabolic ratio. Of 101 Maori subjects pheno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17448893683834b58965fffd6dec6e7f
https://pubmed.ncbi.nlm.nih.gov/8528265

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Fine structural changes in the fibroblasts of canine heart valves prepared for grafting

Autor: J. B. Gavin, J. L. Monro, F. M. Wall, S. C. W. Chalcroft

Publikováno v: Thorax. 28:748-755

Gavin, J. B., Monro, J. L., Wall, F. M., and Chalcroft, S. C. W. (1973). Thorax , 28 , 748-755. Fine structural changes in the fibroblasts of canine heart valves prepared for grafting. Fibroblasts in canine heart valves were examined by light and ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9b718c81f348dca04db5ae8af9a78e
https://doi.org/10.1136/thx.28.6.748

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A method for evaluating the effects of allograft sterilization procedures on the viability of human fibroblasts

Autor: S. C. W. Chalcroft, R. N. Seelye, J. B. Gavin

Publikováno v: Thorax. 29(5)

Chalcroft, S. C. W., Gavin, J. B., and Seelye, R. N. (1974). Thorax , 29 , 539-544. A method for evaluating the effects of allograft sterilization procedures on the viability of human fibroblasts. A semiquantitative method for assessing the effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b4cea5f5e139424eaae5c54da662a6
https://pubmed.ncbi.nlm.nih.gov/4139779

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