Zobrazeno 1 - 10
of 76
pro vyhledávání: '"S C Knight"'
Common genetic variants identify targets for COVID-19 and individuals at high risk of severe disease
Autor:
J E, Horowitz, J A, Kosmicki, A, Damask, D, Sharma, G H L, Roberts, A E, Justice, N, Banerjee, M V, Coignet, A, Yadav, J B, Leader, A, Marcketta, D S, Park, R, Lanche, E, Maxwell, S C, Knight, X, Bai, H, Guturu, D, Sun, A, Baltzell, F S P, Kury, J D, Backman, A R, Girshick, C, O'Dushlaine, S R, McCurdy, R, Partha, A J, Mansfield, D A, Turissini, A H, Li, M, Zhang, J, Mbatchou, K, Watanabe, L, Gurski, S E, McCarthy, H M, Kang, L, Dobbyn, E, Stahl, A, Verma, G, Sirugo, M D, Ritchie, M, Jones, S, Balasubramanian, K, Siminovitch, W J, Salerno, A R, Shuldiner, D J, Rader, T, Mirshahi, A E, Locke, J, Marchini, J D, Overton, D J, Carey, L, Habegger, M N, Cantor, K A, Rand, E L, Hong, J G, Reid, C A, Ball, A, Baras, G R, Abecasis, M A, Ferreira
Publikováno v:
medRxiv
The need to identify and effectively treat COVID-19 cases at highest risk for severe disease remains critical. We identified five common genetic loci (two novel) that modulate both COVID-19 susceptibility and severity, implicating TMPRSS2, IFNAR2, CC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0280def6ca331ba9b219c4a4db248c7d
https://europepmc.org/articles/PMC7899471/
https://europepmc.org/articles/PMC7899471/
Publikováno v:
Tissue Antigens. 16:326-332
One-hundred-forty-one Blacks (135 unrelated) from Kenya and Tanzania have been tissue-typed (HLA-A, B and C loci) as part of a study of host factors involved in Burkitt's lymphoma and naso-pharyngeal carcinoma. Evidence is presented for the existence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db07986361b29adec1d455d6e7dba5b5
https://doi.org/10.1111/j.1399-0039.1980.tb00314.x
https://doi.org/10.1111/j.1399-0039.1980.tb00314.x
Autor:
K. M. Lammers, A. L. Hart, H. O. Al Hassi, N. English, S. Stagg, S. C. Knight, M. A. Kamm, A. J. Stagg, BRIGIDI, PATRIZIA, GIONCHETTI, PAOLO, VITALI, BEATRICE, RIZZELLO, FERNANDO, CAMPIERI, MASSIMO
Purpose: Dendritic cells regulate immune responses to microbial products. We assessed effects of bacterial DNA in the clinically-effective probiotic preparation, VSL#3, on activation, cytokine production and T-cell stimulatory capacity of human dendr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::973d5d788f986c21c2f73d28fee7340a
http://hdl.handle.net/11585/121659
http://hdl.handle.net/11585/121659
Autor:
Jesus Gomez, Francesc E. Borràs, Cristina Navarrete, S C Knight, N English, R. Singh, P Rajananthanan
Publikováno v:
Tissue Antigens. 63:149-157
Two main dendritic cell (DC) subsets have been described in peripheral blood, the myeloid subset or DC1 that is characterized by the presence of CD11c and the plasmacytoid subset or DC2 negative for this marker. The two subsets may perform different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a49f25c42fffe1e1c957cdb67d6844e
https://doi.org/10.1111/j.1399-0039.2004.00159.x
https://doi.org/10.1111/j.1399-0039.2004.00159.x
Autor:
V M Anthony, D Youle, A M Brady, P A Worthington, K A Powell, C A Spinks, S C Knight, A J Greenland, D C Murray, S P Heaney, M A Schulz
Publikováno v:
Annual Review of Phytopathology. 35:349-372
▪ Abstract Fungicides continue to be essential for the effective control of plant diseases. New classes of fungicides with novel modes of action are being developed in the 1990s. These include the strobilurins, phenylpyrroles, anilinopyrimidines, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5db657deabfa93df47172f325cd704f
https://doi.org/10.1146/annurev.phyto.35.1.349
https://doi.org/10.1146/annurev.phyto.35.1.349
Publikováno v:
Proceedings of the Nutrition Society. 72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952f780d70b227e2fc2c11b5afc6d588
https://doi.org/10.1017/s0029665113000293
https://doi.org/10.1017/s0029665113000293
Autor:
S. Patterson, S. C. Knight
Publikováno v:
Reviews in Medical Virology. 5:133-139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09b194e30557ca372c3feff75cfd935
https://doi.org/10.1002/rmv.1980050303
https://doi.org/10.1002/rmv.1980050303
Publikováno v:
Methods in molecular medicine. 64
It is now over 20 years since dendritic cells (DC) were first identified in and isolated from the spleens of mice (1,2) and they continue to be a much-studied population. Only a small proportion of spleen cells are DC, but the large size of the organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cae7e2d176c26ae788b2a8e3983bb376
https://pubmed.ncbi.nlm.nih.gov/21374245
https://pubmed.ncbi.nlm.nih.gov/21374245
Publikováno v:
Proceedings of the Nutrition Society. 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64350e5ae4726b19b6d0a757ea3b26c3
https://doi.org/10.1017/s0029665111000759
https://doi.org/10.1017/s0029665111000759
Differential effect of IL-10 on dendritic cell-induced T cell proliferation and IFN-gamma production
Publikováno v:
The Journal of Immunology. 150:3755-3765
IL-10 has previously been shown to inhibit cytokine production by Th1 cells by blocking macrophage accessory cell function. In this study we demonstrate that dendritic cell-induced Th1 proliferation was unaffected by IL-10, whereas macrophage-stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f1c1bc57b512eca3b0bcdfc05ae9bf6
https://doi.org/10.4049/jimmunol.150.9.3755
https://doi.org/10.4049/jimmunol.150.9.3755