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Autor:
Christian Auclair, Bernard P. Roques, J L Darlix, S C Batson, Jean-François Mouscadet, L Poljak, E Käs, H. De Rocquigny, S. Carteau
Publikováno v:
Journal of Virology. 71:6225-6229
The integrase (IN) protein of the human immunodeficiency virus mediates integration of the viral DNA into the cellular genome. In vitro, this reaction can be mimicked by using purified recombinant IN and model DNA substrates. IN mediates two reaction