Zobrazeno 1 - 10
of 34
pro vyhledávání: '"S C, Pflugfelder"'
Autor:
M. N. V. Ravi Kumar, Meenakshi Arora, Erin M. Scott, M. A. Lepiz, Y. Niu, Raghu Ganugula, Bani K. Mallick, S. C. Pflugfelder
Publikováno v:
Science Advances
Orally delivered double-headed nanoparticle curcumin has potential to treat intraocular inflammation.
Novel approaches circumventing blood-ocular barriers in systemic drug delivery are lacking. We hypothesize receptor-mediated delivery of curcum
Novel approaches circumventing blood-ocular barriers in systemic drug delivery are lacking. We hypothesize receptor-mediated delivery of curcum
Publikováno v:
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 36(2)
To evaluate the regularity of corneal surface and the effect of artificial tears on the corneal surface regularity in dry eye.The surface regularity index (SRI), surface asymmetry index (SAI), the indices of TMS-1 corneal topography system, and poten
Publikováno v:
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 36(5)
To evaluate the expression of type 1 growth factor receptor family [epidermal growth factor receptor (EGFR), ErbB2 and ErbB3] by the epithelium in pterygium so as to understand the pathogenesis of this disorder.The immunofluorescent staining and West
Publikováno v:
Investigative ophthalmologyvisual science. 42(10)
To compare the expression of the pro- and anti-inflammatory forms of interleukin (IL)-1 in the tear fluid and conjunctival epithelium of normal eyes and those with dry-eye disease.The concentrations of IL-1 alpha, IL-1 beta (precursor and mature form
Autor:
A, Solomon, M, Rosenblatt, D Q, Li, Z, Liu, D, Monroy, Z, Ji, B L, Lokeshwar, S C, Pflugfelder
Publikováno v:
Investigative ophthalmologyvisual science. 41(9)
To evaluate the effect of doxycycline on the regulation of interleukin (IL)-1 expression and activity in human cultured corneal epithelium.Human corneal limbal epithelium (HLE) was cultured from explants prepared from limbal rings of donor corneas. P
Publikováno v:
Investigative ophthalmologyvisual science. 41(7)
To evaluate human corneal epithelial culture supernatant and tear fluid for the presence of activators and inhibitors of matrix metalloproteinase (MMP)-9, MMP-3, and tissue inhibitor of metalloproteinase (TIMP)-1, respectively, and to evaluate the ef
Autor:
S C, Pflugfelder, Z, Liu, D, Monroy, D Q, Li, M E, Carvajal, S A, Price-Schiavi, N, Idris, A, Solomon, A, Perez, K L, Carraway
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To evaluate human ocular surface epithelium and tear fluid for the presence of sialomucin complex (MUC4), a high-molecular-weight heterodimeric glycoprotein composed of mucin (ASGP-1) and transmembrane (ASGP-2) subunits.Reverse transcription-polymera
Autor:
Z, Liu, S C, Pflugfelder
Publikováno v:
Ophthalmology. 107(1)
To evaluate the effect of long-term contact lens wear on corneal thickness, curvature, and surface regularity.A prospective, clinic-based, case-control study.A total of 40 eyes of 20 normal subjects and 64 eyes of 35 subjects wearing contact lenses f
Publikováno v:
Investigative ophthalmologyvisual science. 40(11)
To correlate tear fluorescein clearance with interleukin-1alpha (IL-1alpha) concentration and gelatinase B (matrix metalloproteinase [MMP]-9) activity in the tear fluid of patients with ocular rosacea and normal control subjects.Gelatinase activity w
Publikováno v:
Advances in experimental medicine and biology. 438
It is our belief that the pathology of dry eye occurs when systemic androgen levels fall below the threshold necessary for support of secretory function and generation of an anti-inflammatory environment (Fig. 3). When this occurs, both the lacrimal