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pro vyhledávání: '"S C, Mosser"'
Autor:
M D, Schaber, M B, O'Hara, V M, Garsky, S C, Mosser, J D, Bergstrom, S L, Moores, M S, Marshall, P A, Friedman, R A, Dixon, J B, Gibbs
Publikováno v:
The Journal of biological chemistry. 265(25)
Farnesylation of Ras occurs in vivo on a Cys residue in the C-terminal sequence -Cys-Val-Leu-Ser (termed a CAAX box). This modification is required for Ras membrane localization and cell transforming activity. Using [3H]farnesyl-PPi as precursor and