Zobrazeno 1 - 10
of 36
pro vyhledávání: '"S C, Manolagas"'
Autor:
S, Kousteni, T, Bellido, L I, Plotkin, C A, O'Brien, D L, Bodenner, L, Han, K, Han, G B, DiGregorio, J A, Katzenellenbogen, B S, Katzenellenbogen, P K, Roberson, R S, Weinstein, R L, Jilka, S C, Manolagas
Publikováno v:
Cell. 104(5)
The relationship of the classical receptors and their transcriptional activity to nongenotropic effects of steroid hormones is unknown. We demonstrate herein a novel paradigm of sex steroid action on osteoblasts, osteocytes, embryonic fibroblasts, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::996bb4bf240b4b0816c344ce8b8ddf8c
https://pubmed.ncbi.nlm.nih.gov/11257226
https://pubmed.ncbi.nlm.nih.gov/11257226
Publikováno v:
Journal of cellular biochemistry. 79(4)
Interleukin-6 (IL-6)-type cytokines stimulate osteoclast formation by activating the glycoprotein 130 (gp130) receptor subunit on stromal/osteoblastic cells, which in turn leads to signal transducer and activator of transcription 3 (STAT3)-mediated e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79f03b2c4d5007e0fcc54433ef62025d
https://pubmed.ncbi.nlm.nih.gov/10996844
https://pubmed.ncbi.nlm.nih.gov/10996844
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(8)
An increase in osteoblast and osteocyte apoptosis has been demonstrated in mice and humans receiving glucocorticoids and may be involved in the pathogenesis of the associated osteonecrosis. To examine the spatial relationship between osteocyte apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ec9c4c329419c88e0272f1e1058d28b
https://pubmed.ncbi.nlm.nih.gov/10946902
https://pubmed.ncbi.nlm.nih.gov/10946902
Autor:
A, Grey, M A, Mitnick, U, Masiukiewicz, B H, Sun, S, Rudikoff, R L, Jilka, S C, Manolagas, K, Insogna
Publikováno v:
Endocrinology. 140(10)
Parathyroid hormone (PTH) exerts its regulatory effects on calcium homeostasis in part by stimulating the release of calcium from the skeleton. PTH stimulates bone resorption indirectly, by inducing the production by stromal/osteoblastic cells of par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6967d2ee74b3ccf9424418fe38c13db8
https://pubmed.ncbi.nlm.nih.gov/10499526
https://pubmed.ncbi.nlm.nih.gov/10499526
Autor:
B, Lecka-Czernik, I, Gubrij, E J, Moerman, O, Kajkenova, D A, Lipschitz, S C, Manolagas, R L, Jilka
Publikováno v:
Journal of cellular biochemistry. 74(3)
Cells of the bone marrow stroma can reversibly convert among different phenotypes. Based on this and on evidence for a reciprocal relationship between osteoblastogenesis and adipogenesis, we have isolated several murine bone marrow-derived clonal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d166b96a4e4c26963db6ae34d4639268
https://pubmed.ncbi.nlm.nih.gov/10412038
https://pubmed.ncbi.nlm.nih.gov/10412038
Autor:
C A, O'Brien, S C, Manolagas
Publikováno v:
The Journal of biological chemistry. 272(23)
Glycoprotein 130 (gp130), a shared component of all the receptors for the interleukin-6 cytokine family, transduces cytokine signals in part by activating latent cytoplasmic signal transducers and activators of transcription (STATs). STATs subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::249dd2bf2e8ac806e6e4428866a97ae9
https://pubmed.ncbi.nlm.nih.gov/9169475
https://pubmed.ncbi.nlm.nih.gov/9169475
Publikováno v:
Experimental hematology. 23(6)
We have previously demonstrated that ovariectomy causes an increase in the number of colony-forming unit granulocyte/macrophage (CFU-GM) and an upregulation of osteoclastogenesis in mice, both of which are mediated by interleukin-6 (IL-6). IL-6 is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3bf6ab8929be393b38e1b45f99ca2c8
https://pubmed.ncbi.nlm.nih.gov/7768305
https://pubmed.ncbi.nlm.nih.gov/7768305
Publikováno v:
Ciba Foundation symposium. 191
Osteoclasts and osteoblasts, originating in the bone marrow from haemopoietic progenitors and mesenchymal stromal cells, respectively, are responsible for the remodelling of the skeleton throughout adult life. Upon loss of sex steroids, the productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f26b12b367e95ea5270b9561b4cc263
https://pubmed.ncbi.nlm.nih.gov/8582197
https://pubmed.ncbi.nlm.nih.gov/8582197
Publikováno v:
Seminars in nephrology. 14(2)
Monocytes/macrophages and activated (but not resting) lymphocytes as well as certain subsets of thymocytes express the VDR. This protein is indistinguishable from the classical 50-kDa VDR and is encoded by an mRNA with identical nucleotide sequence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::051436c916c5c6f68bebc390ad39300d
https://pubmed.ncbi.nlm.nih.gov/8177980
https://pubmed.ncbi.nlm.nih.gov/8177980
Publikováno v:
The Journal of biological chemistry. 266(12)
The signals controlling the expression of the receptor protein for 1 alpha,25-dihydroxyvitamin D3 in normal human lymphocytes and the relationship of this protein to the classical vitamin D receptor were examined. Lymphocytes activated with the OKT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::225690579889d0fd6a7f0d704be7f923
https://pubmed.ncbi.nlm.nih.gov/1850412
https://pubmed.ncbi.nlm.nih.gov/1850412