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Akademický článek

Active and prospective latent tuberculosis are associated with different metabolomic profiles: clinical potential for the identification of rapid and non-invasive biomarkers

Autor: A. Albors-Vaquer, A. Rizvi, M. Matzapetakis, P. Lamosa, A. V. Coelho, A. B. Patel, S. C. Mande, S. Gaddam, A. Pineda-Lucena, S. Banerjee, L. Puchades-Carrasco

Publikováno v: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1131-1139 (2020)

ABSTRACTAlthough 23% of world population is infected with Mycobacterium tuberculosis (M. tb), only 5–10% manifest the disease. Individuals surely exposed to M. tb that remain asymptomatic are considered potential latent TB (LTB) cases. Such asympto

Externí odkaz: https://doaj.org/article/4724d59493dd46b0b586ea55a9e63d99

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Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity

Autor: R, Chauhan, S C, Mande

Publikováno v: The Biochemical journal. 354(Pt 1)

An alkyl hydroperoxidase (AhpC) has been found frequently to be overexpressed in isoniazid-resistant strains of Mycobacterium tuberculosis. These strains have an inactivated katG gene encoding a catalase peroxidase, which might render mycobacteria su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6876499036f0735877786c8d214d1c0c
https://pubmed.ncbi.nlm.nih.gov/11171096

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Identification of the INO1 gene of Mycobacterium tuberculosis H37Rv reveals a novel class of inositol-1-phosphate synthase enzyme

Autor: N, Bachhawat, S C, Mande

Publikováno v: Journal of molecular biology. 291(3)

1L-myo-inositol (inositol) is vital for the biogenesis of mycothiol, phosphatidylinositol and glycosylphosphatidylinositol anchors linked to complex carbohydrates in Mycobacterium tuberculosis. All these cellular components are thought to play import

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3fc5de2490574e669f228dcbc28a35b7
https://pubmed.ncbi.nlm.nih.gov/10448034

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Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme

Autor: S C, Mande, V, Mainfroid, K H, Kalk, K, Goraj, J A, Martial, W G, Hol

Publikováno v: Protein science : a publication of the Protein Society. 3(5)

The crystal structure of recombinant human triosephosphate isomerase (hTIM) has been determined complexed with the transition-state analogue 2-phosphoglycolate at a resolution of 2.8 A. After refinement, the R-factor is 16.7% with good geometry. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be678e8a99d21eec650791c4a85faff7
https://pubmed.ncbi.nlm.nih.gov/8061610

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Cloning and overexpression of the triosephosphate isomerase genes from psychrophilic and thermophilic bacteria. Structural comparison of the predicted protein sequences

Autor: F, Rentier-Delrue, S C, Mande, S, Moyens, P, Terpstra, V, Mainfroid, K, Goraj, M, Lion, W G, Hol, J A, Martial

Publikováno v: Journal of molecular biology. 229(1)

We focused on the temperature adaptation of triosephosphate isomerase (TIM; E.C. 5.3.1.1.) by comparing the structure of TIMs isolated from bacterial organisms living in either cold or hot environments. The TIM gene from psychrophilic bacteria Moraxe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fac4dbc024a89744089b29cf73fa287
https://pubmed.ncbi.nlm.nih.gov/8421318

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Akademický článek

Efficient Synthesis and Microwave‐Assisted Sonogashira Reactions of Triflate‐Substituted Porphyrin.

Autor: Arcudi, Francesca¹ (AUTHOR), Sartorel, Andrea¹ (AUTHOR), Fortunato, Anna¹ (AUTHOR), Marangoni, Tomas^2,3 (AUTHOR), Demitri, Nicola⁴ (AUTHOR), Maggini, Michele¹ (AUTHOR) michele.maggini@unipd.it, Đorđević, Luka¹ (AUTHOR) luka.dordevic@unipd.it

Publikováno v: European Journal of Organic Chemistry. Nov2023, Vol. 26 Issue 43, p1-7. 7p.

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