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Higher baseline interleukin-1β and TNF-α hamper antidepressant response in major depressive disorder
Autor:
Benedetta Vai, Francesco Benedetti, Mario Gennaro Mazza, Veronica Aggio, Raffaella Zanardi, Sara Poletti, Igor Branchi, Cristina Colombo, Cristina Lorenzi, S. Brioschi, Roberto Furlan
Publikováno v:
Higher baseline interleukin-1β and TNF-α hamper antidepressant response in major depressive disorder
Raised pro-inflammatory immune/inflammatory setpoints, leading to an increased production of peripheral cytokines, have been associated with Major Depressive Disorder (MDD) and with failure to respond to first-line antidepressant drugs. However, the
Autor:
F Mecatti, A Orlando, S Graci, P Palestini, L Maccà, MW Arisido, E Cazzaniga, MC Panzeri, S Brioschi
Background: The aim of the study was to investigate if a parents’ training program on nutritional and oral health behaviours held by health professionals can influence children habits in a sample of kindergartens in Northern Italy.Methods: The stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f34548391e0345070f556c7a506f8e6
http://hdl.handle.net/10281/316196
http://hdl.handle.net/10281/316196
Autor:
Sara Poletti, Davide Ghiglino, Francesco Benedetti, Clara Locatelli, Benedetta Vai, Alice Vitali, S. Brioschi, Alessandro Serretti, M. Riberto, Cristina Colombo, Cristina Lorenzi
Publikováno v:
Journal of Molecular Neuroscience. 65:536-545
Bipolar disorder (BD) is a severe illness characterized by recurrent depressive and manic episodes and by emotional dysregulation. Altered cortico-limbic connectivity could account for typical symptoms of the disorder such as mood instability, emotio
Autor:
Cristina Colombo, Sara Poletti, Francesco Benedetti, S. Brioschi, Cristina Lorenzi, Alessandro Serretti, Alice Vitali, Irene Bollettini
Publikováno v:
Molecular Neurobiology. 56:702-710
Glutamate is the principal excitatory neurotransmitter in the central nervous system. In mature brains, it is critically involved in neuroplasticity and, at high levels, neurotoxicity. The concentrations of glutamate in the extracellular space are ma
Autor:
Andrea Falini, S. Brioschi, Andrea de Bartolomeis, Veronica Aggio, Francesco Benedetti, M. Riberto, Elena Mazza, Sara Poletti, Benedetta Vai, Clara Locatelli, Elisa M T Melloni, Alice Vitali, Irene Bollettini, Cristina Colombo, Cristina Lorenzi
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81:88-95
Background The Homer family of postsynaptic scaffolding proteins plays a crucial role in glutamate-mediated synaptic plasticity, a phenotype associated with Bipolar Disorder (BD). Homer is a target for antidepressants and mood stabilizers. The AA ris
Akademický článek
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Autor:
J. M. Sanchez-Caro, Patrick Weydt, S. Jahnert, A. Hoffmann, Teodora Stella Wijasa, Róisín M. McManus, A. Van der Perren, Sergio Castro-Gomez, A. Ardura-Fabregat, Yiyi Yang, Peter-Andreas Löschmann, Kitty Reemst, Antonio Boza-Serrano, Michael T. Heneka, A. Webers, Leonardo Iaccarino, Gary E. Landreth, Géraldine Gelders, T. Dierkes, S. Brioschi, Erik Boddeke, K. Kuhbandner, Agnes Paulus, A. Vautheny, A. Tiberi, Carmen Venegas, Xianyuan Xiang, K. Ceyzériat, Cira Dansokho, Lianne Hoeijmakers, Niklas Lonnemann
Publikováno v:
CNS drugs 31(12), 1057-1082 (2017). doi:10.1007/s40263-017-0483-3
CNS Drugs
CNS Drugs
Over the past few decades, research on Alzheimer's disease (AD) has focused on pathomechanisms linked to two of the major pathological hallmarks of extracellular deposition of beta-amyloid peptides and intra-neuronal formation of neurofibrils. Recent
Autor:
Sara Dallaspezia, Sara Poletti, Francesco Benedetti, Veronica Aggio, S. Brioschi, Cristina Colombo
Publikováno v:
Psychiatry and Clinical Neurosciences. 71:309-317
Aim Studies have demonstrated neuropsychological deficits across a variety of cognitive domains in depression. These deficits are observable both in major depression (MDD) and in bipolar disorder (BD) and are present in each phase of the disorders, i