Zobrazeno 1 - 10 of 629 pro vyhledávání: '"S Boland"'
1
Akademický článek
Automated spatial omics landscape analysis approach reveals novel tissue architectures in ulcerative colitis
Autor: Derek R. Holman, Samuel J. S. Rubin, Mariusz Ferenc, Elizabeth A. Holman, Alexander N. Koron, Robel Daniel, Brigid S. Boland, Garry P. Nolan, John T. Chang, Stephan Rogalla
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The utility of spatial omics in leveraging cellular interactions in normal and diseased states for precision medicine is hampered by a lack of strategies for matching disease states with spatial heterogeneity-guided cellular annotations. Her
Externí odkaz: https://doaj.org/article/9cf3949b48914fbdaf084cb324a67561
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2
Akademický článek
Hometronics – accessible production of graphene suspensions for health sensing applications using only household items
Autor: Adel K. A. Aljarid, Jasper Winder, Cencen Wei, Arvind Venkatraman, Oliver Tomes, Aaron Soul, Dimitrios G. Papageorgiou, Matthias E. Möbius, Conor S. Boland
Publikováno v: npj 2D Materials and Applications, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Nanoscience at times can seem out of reach to the developing world and the general public, with much of the equipment expensive and knowledge seemingly esoteric to nonexperts. Using only cheap, everyday household items, accessible research w
Externí odkaz: https://doaj.org/article/f34bb53306a44d078fcf7871b8a0b239
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3
Akademický článek
The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn’s Disease but Not Ulcerative Colitis Patients
Autor: Young Su Park, Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J. Docherty, Brigid S. Boland, William J. Sandborn, Declan F. McCole
Publikováno v: Pharmaceutics, Vol 15, Iss 3, p 811 (2023)
The prostone analog, lubiprostone, is approved to manage constipation-predominant irritable bowel syndrome. Lubiprostone also protects intestinal mucosal barrier function in animal models of colitis. The aim of this study was to determine if lubipros
Externí odkaz: https://doaj.org/article/5f068f2b880b4b1ab6c054eb34c860c1
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4
Akademický článek
RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB ActivationSummary
Autor: Jerry Wong, Ricard Garcia-Carbonell, Matija Zelic, Samuel B. Ho, Brigid S. Boland, Shih-Jing Yao, Shalin A. Desai, Soumita Das, Núria Planell, Philip A. Harris, Joan Font-Burgada, Koji Taniguchi, John Bertin, Azucena Salas, Manolis Pasparakis, Pete J. Gough, Michelle Kelliher, Michael Karin, Monica Guma
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)
Background and Aims: Tumor necrosis factor (TNF) is a major pathogenic effector and a therapeutic target in inflammatory bowel disease (IBD), yet the basis for TNF-induced intestinal epithelial cell (IEC) death is unknown, because TNF does not kill n
Externí odkaz: https://doaj.org/article/4bf9bd1fe4534fd6a45b7e148464a13a
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5
Akademický článek
Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads
Autor: Jon G. Sanders, Sergey Nurk, Rodolfo A. Salido, Jeremiah Minich, Zhenjiang Z. Xu, Qiyun Zhu, Cameron Martino, Marcus Fedarko, Timothy D. Arthur, Feng Chen, Brigid S. Boland, Greg C. Humphrey, Caitriona Brennan, Karenina Sanders, James Gaffney, Kristen Jepsen, Mahdieh Khosroheidari, Cliff Green, Marlon Liyanage, Jason W. Dang, Vanessa V. Phelan, Robert A. Quinn, Anton Bankevich, John T. Chang, Tariq M. Rana, Douglas J. Conrad, William J. Sandborn, Larry Smarr, Pieter C. Dorrestein, Pavel A. Pevzner, Rob Knight
Publikováno v: Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples. We term this approach
Externí odkaz: https://doaj.org/article/42e8537276ff4a9bba279cd526759a65
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9
Enhancing untargeted metabolomics using metadata-based source annotation
Autor: Julia M. Gauglitz, Kiana A. West, Wout Bittremieux, Candace L. Williams, Kelly C. Weldon, Morgan Panitchpakdi, Francesca Di Ottavio, Christine M. Aceves, Elizabeth Brown, Nicole C. Sikora, Alan K. Jarmusch, Cameron Martino, Anupriya Tripathi, Michael J. Meehan, Kathleen Dorrestein, Justin P. Shaffer, Roxana Coras, Fernando Vargas, Lindsay DeRight Goldasich, Tara Schwartz, MacKenzie Bryant, Gregory Humphrey, Abigail J. Johnson, Katharina Spengler, Pedro Belda-Ferre, Edgar Diaz, Daniel McDonald, Qiyun Zhu, Emmanuel O. Elijah, Mingxun Wang, Clarisse Marotz, Kate E. Sprecher, Daniela Vargas-Robles, Dana Withrow, Gail Ackermann, Lourdes Herrera, Barry J. Bradford, Lucas Maciel Mauriz Marques, Juliano Geraldo Amaral, Rodrigo Moreira Silva, Flavio Protasio Veras, Thiago Mattar Cunha, Rene Donizeti Ribeiro Oliveira, Paulo Louzada-Junior, Robert H. Mills, Paulina K. Piotrowski, Stephanie L. Servetas, Sandra M. Da Silva, Christina M. Jones, Nancy J. Lin, Katrice A. Lippa, Scott A. Jackson, Rima Kaddurah Daouk, Douglas Galasko, Parambir S. Dulai, Tatyana I. Kalashnikova, Curt Wittenberg, Robert Terkeltaub, Megan M. Doty, Jae H. Kim, Kyung E. Rhee, Julia Beauchamp-Walters, Kenneth P. Wright, Maria Gloria Dominguez-Bello, Mark Manary, Michelli F. Oliveira, Brigid S. Boland, Norberto Peporine Lopes, Monica Guma, Austin D. Swafford, Rachel J. Dutton, Rob Knight, Pieter C. Dorrestein
Publikováno v: Nature biotechnology, vol 40, iss 12
Nat Biotechnol
Human untargeted metabolomics studies annotate only ~10% of molecular features. We introduce reference-data-driven analysis to match metabolomics tandem mass spectrometry (MS/MS) data against metadata-annotated source data as a pseudo-MS/MS reference
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadcc5a8ebaed4c919d942163887bc61
https://doi.org/10.1038/s41587-022-01368-1
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