Výsledky vyhledávání - "S B Viegas, Carla"

Sturgeon osteocalcin shares structural features with matrix gla protein evolutionary relationship and functional implications

Autor: S B Viegas, Carla, Simes, Dina, Williamson, Matthew K., Cavaco, Sofia, Laizé, Vincent, Price, Paul A., Leonor Cancela, M.

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Osteocalcin (OC) and matrix Gla protein (MGP) are considered evolutionarily related because they share key structural features, although they have been described to exert different functions. In this work, we report the identification and characteriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ff11edeb9ac2dda54a3da7f0ee7f3e2

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Identification of an osteocalcin isoform in fish with a large acidic prodomain

Autor: Laizé, Vincent, S B Viegas, Carla, Price, P. A., Cancela, Leonor

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Osteocalcin is a small, secreted bone protein whose gene consists of four exons. In the course of analyzing the structure of fish osteocalcin genes, we recently found that the spotted green pufferfish has two possible exon 2 structures, one of 15 bp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e6756f7351f56a1f36ac569357a9923
https://hdl.handle.net/10400.1/4296

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Whole-genome sequence analysis: Evidences for new osteocalcin isoforms in fish and tetrapods

Autor: Laizé, Vincent, Gavaia, Paulo J., S B Viegas, Carla, Cancela, Leonor

The evolution of calcified tissues is a defining feature in vertebrate evolution. Investigating evolution of proteins involved in tissue calcification should help elucidate how calcified tissues have evolved. Osteocalcin (OC) is a small calcium-bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1505::f3281c50daf0acdee6a54e8abd44c398
https://hdl.handle.net/10400.1/4506

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Identification of a new pebp2 alpha A2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro

Autor: Pinto, Jorge, Conceição, Natércia, S B Viegas, Carla, Leite, Ricardo, Hurst, L. D., Kelsh, R. N., Leonor Cancela, M.

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Introduction: RUNX2 (also known as CBFA1/Osf2/AML3/PEBP2 alpha A) is a transcription factor essential for bone formation in mammals, as well as for osteoblast and chondrocyte differentiation, through regulation of expression of several bone- and cart

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1b8397f20a4006ea99ef18d121bef8aa
https://hdl.handle.net/10400.1/11176

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Proteínas gla do osso e cartilagem: importância dos anfíbios e peixes como modelos biológicos para elucidação da sua função e evolução - gla proteins in bone and cartilage: the importance of fish and amphibian models to understand their function and evolution

Autor: Cancela, Leonor, Laizé, Vincent, Simes, D, Gavaia, Paulo J., Conceição, N., S B Viegas, Carla, Pombinho, A. R., Marques, S., Fidalgo, J., Braga, D.

Gla proteins, as the name indicates, undergo a post-translation modification where specific glutamic acid residues are γ-carboxylated through the action of the ubiquitous enzyme γ-carboxylase and using vitamin K as cofactor. Therefore, these protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1505::8a48c97333d72206c4f7d6b7f7a94931
https://hdl.handle.net/10400.1/4398

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Cloning and ontogenetic expression of the oligopeptide transporter PepT1 (Solute carrier family 15, member 1), in fed and starved larval Atlantic cod, Gadus morhua L

Autor: Rønnestad, I., Gavaia, Paulo J., S B Viegas, Carla, Cancela, Leonor

Functional characteristics of marine fish larvae digestive system at the onset of exogenous feeding have long been a subject for discussion. Absorption of digested proteins in vertebrates has been shown to include transporter systems for single amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1505::d94d3b301be77ef38416eca4387e13a6
https://hdl.handle.net/10400.1/4575

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Gla proteins as markers for studies of skeletal development and malformations in new aquaculture fish species (Pagrus auriga, Diplodus sargo and Scophtalmus maximus)

Autor: S B Viegas, Carla, Gavaia, Paulo J., Ortiz-Delgado, J. B., Sarasquete, C., Cancela, Leonor

Evaluation of the onset and the development of skeletal structures during larval ontogeny of commercially important species in southern Iberia Peninsula and Mediterranean area (...) is essential for the successful production of high quality fish. PG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1505::525af38f331c505cd916e1046a20b7fc
https://hdl.handle.net/10400.1/4452

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Expression of the oligopeptide transporter PepT1 (Solute carrier family 15, member 1), in fed and starved larval Zebra fish (Danio rerio)

Autor: Brito, A. B., Rønnestad, I., Gavaia, Paulo J., S B Viegas, Carla, Cancela, Leonor

Fish embryos develop while utilizing yolk nutrients supplied by the (...). There normally exists a "first feeding window" between when the larvae (...) able to ingest exogenous feed,and the "point of no return" where (...) exhausted its yolk reserves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1505::c05f6eb5d9b176625e7cc49ed5a4f170
https://hdl.handle.net/10400.1/4424

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