Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S B Bowes"'
Autor:
Jimmy D. Bell, J. Gibney, Nicola Jackson, Anne Umpleby, S. B. Bowes, Richard H. Jones, M Stolinski, Kevin C.R. Baynes, Fariba Shojaee-Moradie, E. L. Thomas, Martin Whyte, D. Lovell, Claire Pentecost
Publikováno v:
Diabetologia. 50:404-413
AIMS/HYPOTHESIS: It is not known whether the beneficial effects of exercise training on insulin sensitivity are due to changes in hepatic and peripheral insulin sensitivity or whether the changes in insulin sensitivity can be explained by adaptive ch
Autor:
Emanuel Christ, David Russell-Jones, S B Bowes, Ian J. Gowrie, Anne Umpleby, P Croos, Roman Hovorka, Peter H. Sönksen, P V Carroll, Nicola Jackson
Publikováno v:
Diabetes. 49:789-796
Type 1 diabetes is associated with abnormalities of the growth hormone (GH)-IGF-I axis. Such abnormalities include decreased circulating levels of IGF-I. We studied the effects of IGF-I therapy (40 microg x kg(-1) x day(-1)) on protein and glucose me
Autor:
S. B. Bowes
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 82:243-246
Autor:
S. B. Bowes, Anne Umpleby, Peter H. Sönksen, Clara Lowy, Nicola Jackson, T. R. Hennessy, M. A. Boroujerdi, J. J. Benn
Publikováno v:
Diabetologia. 39:976-983
Gestational diabetes affects 2-3% of pregnant women and is associated with foetal complications including macrosomia and an increased likelihood of developing diabetes in later life. We have therefore studied seven women with gestational diabetes and
Autor:
D. L. RUSSELL-JONES, A. T. BATES, A. M. UMPLEBY, T. R. HENNESSY, S. B. BOWES, K. D. HOPKINS, N. JACKSON, J. KELLY, F. SHOJAEE-MORADIE, R. H. JONES, P. H. SONKSEN
Publikováno v:
European Journal of Clinical Investigation. 25:403-411
The metabolic and cardiovascular effects of recombinant human IGF-I were compared to insulin in six normal subjects. Subjects were studied twice and intravenously received an infusion of [6,6-2H2]glucose (0-480 min) and in random order either IGF-I 2
Autor:
Richard H. Jones, Peter H. Sönksen, Anne Umpleby, S B Bowes, A. J. Weissberger, J. M. Kelly, M. J. Thomason, David Russell-Jones
Publikováno v:
Clinical Endocrinology. 38:427-431
OBJECTIVE Growth hormone treatment given to adult growth hormone deficient patients leads to an increase in lean body mass by an unknown mechanism. The aim of this study was to investigate the actions of growth hormone treatment on protein metabolism
Autor:
S B, Bowes, M, Umpleby, M H, Cummings, N C, Jackson, P V, Carroll, C, Lowy, P H, Sönksen, D L, Russell-Jones
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(1)
Cushing's syndrome is characterized by central obesity and muscle wasting. As GH is anabolic, it may be able to counteract the loss of body protein. To evaluate the potential therapeutic use of GH preoperatively, eight patients with Cushing's syndrom
Publikováno v:
The Journal of endocrinology. 148(3)
The net catabolic effect of glucocorticoids on protein metabolism is well documented but the acute and chronic effect of glucocorticoids on protein breakdown remains controversial. In the present studies protein breakdown was measured by the release
Autor:
Richard H. Jones, Peter H. Sönksen, J.M. Kelly, A. M. Umpleby, T. R. Hennessy, K. D. Hopkins, S. B. Bowes, Fariba Shojaee-Moradie, David Russell-Jones, Nicola Jackson
Publikováno v:
The American journal of physiology. 267(4 Pt 1)
Insulin-like growth factor I (IGF-I) is thought to mediate the anabolic action of growth hormone. A glucose and amino acid clamp technique was used to investigate the effects of a 3-h intravenous infusion of either 43.7 pmol.kg-1.min-1 (20 micrograms
Publikováno v:
Clinical endocrinology. 39(5)
Summary OBJECTIVE Results from studies on the effect of glucocor-ticosteroids on protein turnover in both rat and man have been conflicting. The aim of this study was to investigate the primary cause of muscle wasting in patients with Cushing's syndr