Zobrazeno 1 - 10
of 19
pro vyhledávání: '"S B, Rodan"'
Autor:
T. Prueksaritanont, C. Fernandez-Metzler, Y. Meng, A. Barrish, W. Halczenko, S. B. Rodan, J. H. Hutchinson, M. E. Duggan, J. H. Lin
Publikováno v:
Xenobiotica. 34:103-115
Autor:
T, Prueksaritanont, C, Fernandez-Metzler, Y, Meng, A, Barrish, W, Halczenko, S B, Rodan, J H, Hutchinson, M E, Duggan, J H, Lin
Publikováno v:
Xenobiotica. 34:103-115
1. The disposition of 3-[2-oxo-3-[3-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl) propyl]-imidazolidin-1-yl]-3(S)-(6-methoxy-pyridin-3-yl)propionic acid (compound A), a potent and selective alpha(v)beta(3) antagonist, was characterized in several anima
Autor:
M E, Duggan, L T, Duong, J E, Fisher, T G, Hamill, W F, Hoffman, J R, Huff, N C, Ihle, C T, Leu, R M, Nagy, J J, Perkins, S B, Rodan, G, Wesolowski, D B, Whitman, A E, Zartman, G A, Rodan, G D, Hartman
Publikováno v:
Journal of medicinal chemistry. 43(20)
Modification of the potent fibrinogen receptor (alpha(IIb)beta(3)) antagonist 1 generated compounds with high affinity for the vitronectin receptor alpha(v)beta(3). Sequential modification of the basic N-terminus of 1 led to the identification of the
Publikováno v:
Journal of cellular physiology. 179(3)
Clonal cell lines were established from adult rat tibia cells immortalized with SV-40 large T antigen. One clone (TRAB-11), in which retinoic acid (RA) induced alkaline phosphatase (AP) activity, was selected for further study. The TRAB-11 cells expr
Autor:
S B, Rodan, G A, Rodan
Publikováno v:
The Journal of endocrinology.
Integrins are a large family of heteromeric cell surface receptors composed of non-covalently bound alpha and beta subunits which interact with extracellular matrix molecules, serum constituents and the adhesion molecules of the immunoglobulin family
Publikováno v:
Clinical orthopaedics and related research. (313)
Bone formation is linked closely to angiogenesis. Because prostaglandin E2 (PGE2) is a potent stimulator of bone formation, its effects were evaluated on vascular endothelial growth factor, a secreted endothelial cell-specific mitogen, and a potent a
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(4)
IL-1 is a potent bone resorbing agent. Its mechanism of action is unknown, but the presence of osteoblasts was shown to be necessary for IL-1 stimulation of bone resorption by isolated osteoclasts. This study examines the presence of IL-1R and IL-1 e
Autor:
Karl L. Insogna, A E Broadus, G A Rodan, Gregory R. Mundy, S B Rodan, Agnès Vignery, S M D'Souza, Andrew F. Stewart, D R Bertolini
Publikováno v:
Journal of Clinical Investigation. 72:1511-1515
The culture media of three cell lines, a human prostate carcinoma (PC3), a rat Leydig cell tumor (Rice-500), and a rat carcinosarcoma (WRC-256), that were derived from tumors associated with humoral hypercalcemia of malignancy (HHM), were examined fo
Autor:
L S, Cutler, S B, Rodan
Publikováno v:
Journal of embryology and experimental morphology. 36(2)
To investigate membrane changes in development of the exocrine cells of the rat submandibular gland (SMG), biochemical and cytochemical studies of adenylate cyclase activity were performed on prenatal and postnatal glands. SMG rudiments and glands we
Publikováno v:
The Journal of biological chemistry. 264(33)
In rat osteosarcoma (ROS 17/2.8) cells, which express osteoblastic features in culture, basic fibroblast growth factor (bFGF) reduces the level of alkaline phosphatase, type I collagen, and osteocalcin mRNA and increases osteopontin mRNA, independent