Zobrazeno 1 - 7 of 7 pro vyhledávání: '"S B, DeMattos"'
1
Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers
Autor: R.J. Anziano, Glen Apseloff, S. B. Demattos, N. Gerber, Keith D. Wilner
Publikováno v: British Journal of Clinical Pharmacology. 49:43-47
Aims To determine whether ziprasidone alters the metabolizing activity of the 2D6 isoenzyme of cytochrome P450 (CYP2D6).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d97d872b8658c8d89267d645714f545c
https://doi.org/10.1046/j.1365-2125.2000.00152.x
Zobrazit plný text záznamu
2
5,7-Dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H-pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: A Potent and Centrally-Selective Inhibitor of Acetylcholinesterase
Autor: Douglas S. Chapin, J. L. Ives, Yuhpyng L. Chen, Dane R. Liston, Butler Todd W, S. B. Demattos, S.B. Jones, Arthur Adam Nagel, Anabella Villalobos, Deane M. Nason
Publikováno v: Journal of Medicinal Chemistry. 38:2802-2808
A series of N-benzylpiperidines (2a-d, 10) with novel isoxazole-containing tricycles has been prepared. This series has shown potent in vitro inhibition of the enzyme acetylcholinesterase (AChE), with IC 50 s = 0.33-3.6 nM. Compound 2a was the most p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8551d1d9d25d8c3d057cc2328da0bff2
https://doi.org/10.1021/jm00015a002
Zobrazit plný text záznamu
4
Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers
Autor: K D, Wilner, S B, Demattos, R J, Anziano, G, Apseloff, N, Gerber
Publikováno v: British journal of clinical pharmacology. 49
To determine whether ziprasidone alters the metabolizing activity of the 2D6 isoenzyme of cytochrome P450 (CYP2D6).Twenty-four healthy young subjects aged 18-45 years were screened for CYP2D6 metabolizing activity and shown to be extensive metabolize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f98995674ae040d4ecff2855cf327f9b
https://pubmed.ncbi.nlm.nih.gov/10771453
Zobrazit plný text záznamu
5
CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects
Autor: T A, Rugsley, M D, Davis, H C, Akunne, L W, Cooke, S Z, Whetzel, R G, MacKenzie, Y H, Shih, D H, van Leeuwen, S B, DeMattos, L M, Georgic
Publikováno v: The Journal of pharmacology and experimental therapeutics. 274(2)
The receptor binding and biochemical effects of the putative dopamine (DA) partial agonist CI-1007 ([R(+)-1,2,3,6-tetrahydro-4-phenyl- 1-[(3-phenyl-3-cyclohexen-1-yl)methyl]pyridine] maleate) and potential antipsychotic were evaluated with a variety
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b77f832f05addd4b7d8a41166556223f
https://pubmed.ncbi.nlm.nih.gov/7636753
Zobrazit plný text záznamu
6
5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety
Autor: A, Villalobos, T W, Butler, D S, Chapin, Y L, Chen, S B, DeMattos, J L, Ives, S B, Jones, D R, Liston, A A, Nagel, D M, Nason
Publikováno v: Journal of medicinal chemistry. 38(15)
A series of N-benzylpiperidines (2a-d, 10) with novel isoxazole-containing tricycles has been prepared. This series has shown potent in vitro inhibition of the enzyme acetylcholinesterase (AChE), with IC50S = 0.33 - 3.6 nM. Compound 2a was the most p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2433ce61e7b440f087752df9d6f05f33
https://pubmed.ncbi.nlm.nih.gov/7636841
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje