Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S B, Aleshkov"'
Publikováno v:
The Journal of biological chemistry. 271(35)
Plasminogen activator inhibitor type 1 (PAI-1) is a fast acting inhibitor of plasminogen activators (PAs). In accordance with other serpins, PAI-1 is thought to undergo a conformational change upon reactive center cleavage. In this study we have deve
Autor:
A G, Sarafanov, M Ia, Timofeeva, S B, Aleshkov, N S, Kupriianova, V M, Bannikov, V M, Zakhar'ev, A A, Baev
Publikováno v:
Molekuliarnaia biologiia. 28(4)
Fragments overlapping the tPA gene and its 5'- and 3'-flanking regions were isolated from human liver DNA library cloned in lambda Charon4A vector. A BglII fragment comprising the 3' end and the adjacent genomic region (total length 3.7 kb) was subcl
Publikováno v:
Molekuliarnaia biologiia. 28(3)
We have characterized a number of recombinant cell lines established with BPV1 and Lx1 (containing duplication of LCR-E6-E7 sequence) vectors on the basis of C127 cells. It had been shown that Lx1 based vectors possess the higher number of intracellu
Publikováno v:
Molekuliarnaia biologiia. 25(5)
A number of recombinant cell lines which produce human tissue plasminogen activator (tPA) was obtained using different hosts--mouse, rat, hamster, simian and human cell lines. All types of recombinant lines secreted active r-tPA into conditioned medi
Publikováno v:
Molekuliarnaia biologiia. 25(5)
We have constructed a number of vectors which include transcriptional unit of human tPA cDNA and 100% BPV-1 DNA or 100% Lx DNA (mutant BPV variant with tandem duplication of LCR-E6-E7 region). Additional HSV-1 Tk-promoter was inserted in the flanks o
Publikováno v:
Doklady Akademii nauk SSSR. 318(6)
Publikováno v:
Doklady Akademii nauk SSSR. 309(3)