Zobrazeno 1 - 10
of 60
pro vyhledávání: '"S B, Akopov"'
Autor:
S. B. Akopov, E. V. Snezhkov, M. V. Konovalova, M. A. Kostromina, R. S. Esipov, E. V. Svirshchevskaya
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1099-1106 (2024)
Animal tumor models are used for preclinical studies of drugs and cancer therapy. The aim of this work was to analyze the growth of murine pancreatic tumor cells Pan02, carrying GFP marker, injected subcutaneously (s. c.), intraperitoneally (i. p.) o
Externí odkaz:
https://doaj.org/article/a1d3227b956b4e9d9334eea413e25392
Publikováno v:
Acta naturae. 14(3)
The family of genes containing C2H2 zinc finger domains, which has more than 700 members, is one of the largest in the genome. Of particular interest are C2H2 genes with potential tissue-specific transcription, which determine the functional properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bc46f45eb869ee1304d42b99ee7ce41
https://pubmed.ncbi.nlm.nih.gov/36348719
https://pubmed.ncbi.nlm.nih.gov/36348719
Publikováno v:
Molecular Genetics, Microbiology and Virology. 34:220-227
One of the most popular nonviral delivery systems for gene therapy constructs are carriers based on polyethylenimine (PEI) DNA complexes. A number of disadvantages associated with the lack of targeted delivery and increased cytotoxicity are overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d3bfeac9cda49937464a379252914a
https://doi.org/10.3103/s0891416819040037
https://doi.org/10.3103/s0891416819040037
SOX9 as One of the Central Units of Regulation Axis of Pancreas Embryogenesis and Cancer Progression
Publikováno v:
Molecular Genetics, Microbiology and Virology. 34:159-169
The embryonic development of all body systems is controlled by coordinated interactions of a group of genes encoding master regulators of development, which determine the fate of cells in the process of differentiation. These genes are often involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327799006f20189458b8489d06a3aa11
https://doi.org/10.3103/s0891416819030030
https://doi.org/10.3103/s0891416819030030
Publikováno v:
Russian Journal of Genetics. 55:523-534
The emergence of genetic diseases and evolutionary processes are associated with the flow of genetic information from one generation to another, in which genetic information carried by gametes can be changed by the appearance of de novo germline muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275b525af4c8101d6c1080a952b60df1
https://doi.org/10.1134/s1022795419050144
https://doi.org/10.1134/s1022795419050144
Publikováno v:
Gene. 603:15-20
Earlier, it was reported that the strong cytomegalovirus enhancer can activate the cytomegalovirus promoter in trans, i.e. as a separate plasmid co-transfected with a promoter-reporter gene construct. Here we demonstrate that the ability of enhancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351bb05d5b4369cb6d40be0053771b41
https://doi.org/10.1016/j.gene.2016.12.005
https://doi.org/10.1016/j.gene.2016.12.005
Autor:
N. V. Petrova, Olga V. Iarovaia, S. B. Akopov, Sergey V. Razin, D. A. Didych, Lev G. Nikolaev, E. S. Kotova
Publikováno v:
Acta Naturae. 8:90-97
A systematic search for DNA fragments containing potential CTCF transcription factor binding sites in the chicken alpha-globin domain and its flanking regions was performed by means of the two-dimension electrophoretic mobility shift assay. For the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3354a786ee1e29978de3447a85b57834
https://doi.org/10.32607/20758251-2016-8-1-90-97
https://doi.org/10.32607/20758251-2016-8-1-90-97
Autor:
N. P. Sharova, S. B. Akopov, T. M. Astakhova, Ruslan R. Safarov, Pavel A. Erokhov, Natalia I. Chupikova, A. V. Morozov, Maria I. Mikhailovskaya
Publikováno v:
Cancers
Volume 10
Issue 10
Cancers, Vol 10, Iss 10, p 351 (2018)
Volume 10
Issue 10
Cancers, Vol 10, Iss 10, p 351 (2018)
Tumor growth is associated with elevated proteasome expression and activity. This makes proteasomes a promising target for antitumor drugs. Current antitumor drugs such as bortezomib that inhibit proteasome activity have significant side effects. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2c6d6242197b903459f6b0e09dad24
http://europepmc.org/articles/PMC6209890
http://europepmc.org/articles/PMC6209890
Publikováno v:
Biopolymers and Cell, Vol 30, Iss 4, Pp 260-272 (2014)
The CTCF transcription factor is thought to be one of the main participants in various gene regulatory networks including transcription activation and repression, formation of independently functioning chromatin domains, regulation of imprinting etc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ebf791c37ca60cdb7d1dd585db2f79
https://doi.org/10.7124/bc.00089f
https://doi.org/10.7124/bc.00089f
Publikováno v:
Biochemistry (Moscow). 78:879-883
The chicken gene for transcription factor CTCF was expressed in COS-1 mammalian cells. The CTCF protein containing polyhistidine tag was partially purified using metallo-affinity and ion-exchange chromatography. The expressed protein localized in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad3d45a810b02ebefdc1bb90ece90b8
https://doi.org/10.1134/s0006297913080038
https://doi.org/10.1134/s0006297913080038