Výsledky vyhledávání

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Autor: Sarah E. Stewart, Ilia Voskoboinik, Phillip I. Bird, Sarah Ellis, Olivia Susanto, M Hagn, Joseph A. Trapani, Nigel J. Waterhouse, S Asquith, Daniella Brasacchio, Karin A Sedelies

Publikováno v: Cell Death & Differentiation. 20:1183-1193

Human and mouse granzyme (Gzm)B both induce target cell apoptosis in concert with pore-forming perforin (Pfp); however the mechanisms by which other Gzms induce non-apoptotic death remain controversial and poorly characterised. We used timelapse micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbb8ae660d5f07c3785799aedab7ddf
https://doi.org/10.1038/cdd.2013.59

Zobrazit plný text záznamu

Perturbed desmosomal cadherin expression in grainy head-like 1-null mice

Autor: Alana Auden, Loretta Cerruti, Lin-Lin Zhao, Nikki R. Hislop, Sarah Ellis, Stephen M. Jane, Jacinta Caddy, Rodney Sinclair, Tomasz Wilanowski, S Asquith, Stephen B. Ting, John M. Cunningham

Publikováno v: The EMBO Journal. 27:886-897

In Drosophila, the grainy head (grh) gene plays a range of key developmental roles through the regulation of members of the cadherin gene family. We now report that mice lacking the grh homologue grainy head-like 1 (Grhl1) exhibit hair and skin pheno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8baba3d12507232e6519c25862e4f570
https://doi.org/10.1038/emboj.2008.24

Zobrazit plný text záznamu

Studies in the lightfastness of nitrodiphenylamine dyes

Autor: Hal S. Blair, Aidan C. Hamill, Raymond S. Asquith

Publikováno v: Journal of Applied Chemistry and Biotechnology. 26:253-258

Studies of the photofading of nitrodiphenylamine dyes have been made in ethanolic solution. It has been shown that the presence of oxygen during photoirradiation of the solution acts as an inhibitor, causing an induction period before degradation com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5311b20657674d39eb2e5a03e4aadf63
https://doi.org/10.1002/jctb.5020260139

Zobrazit plný text záznamu

Degradative addition reactions in relation to protein-bound cystine

Autor: Michael S. Otterburn, R. S. Asquith, K. W. Yeung

Publikováno v: Journal of Chemical Technology and Biotechnology. 29:384-389

A study has been made of the degradation of protein-bound cystine, in various proteins, when degraded by alkali in the presence of aliphatic amines. This shows that the structure of amine has a significant effect on the rate of degradation of the cys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce4cddc64a8ce3ff8f2cdb6573282a2b
https://doi.org/10.1002/jctb.503290610

Zobrazit plný text záznamu

Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women

Autor: M Stubbins, S Varsani, N Crocker, A Handley, A Yeo, S Asquith, P Boyd, D Montgomery, G A Hicks, B Bahari, I Taylor, I Purvis, S Lumsden, D H Alpers, T Saunders, R Rallan, George E. Dukes, A Knaggs

Publikováno v: Gut. 53:1452-1458

Background and aims: Serotonin (5-hydroxtryptamine, 5-HT) is an important factor in gut function, playing key roles in intestinal peristalsis and secretion, and in sensory signalling in the brain-gut axis. Removal from its sites of action is mediated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3f4a6c63c467a7fa63b765baacf9c1
https://doi.org/10.1136/gut.2003.035451

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Elektronická kniha

Chemistry of Natural Protein Fibers

Autor: R. S. Asquith

This volume arose originally from the complaints of the editor's students, both undergraduate and postgraduate, that there was no modern book on protein fibers which told enough about protein science and chemical tech nologies related to fibers. By

Zobrazit plný text záznamu

An innovative triple immunogold labeling method to investigate the hemopoietic stem cell niche in situ

Autor: Susan K. Nilsson, Brenda Williams, Ivan Bertoncello, Sarah Ellis, S Asquith

Publikováno v: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 15(5)

The ultrastructural study of rare cells within their nichein situis very difficult. We have developed a method for locating individual transplanted cells and simultaneously identifying and analyzing the molecules and cellular phenotypes surrounding t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a219967811e9ea5c161e0e5641d778
https://pubmed.ncbi.nlm.nih.gov/19754979

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání