Zobrazeno 1 - 10
of 174
pro vyhledávání: '"S Ansar, Ahmed"'
Autor:
Leila Abdelhamid, Jiangdi Mao, Xavier Cabana-Puig, Jing Zhu, Brianna K. Swartwout, Michael R. Edwards, James C. Testerman, Jacquelyn S. Michaelis, Irving Coy Allen, S. Ansar Ahmed, Xin M. Luo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
NLRP12 has dual roles in shaping inflammation. We hypothesized that NLRP12 would modulate myeloid cells and T cell function to control systemic autoimmunity. Contrary to our hypothesis, the deficiency of Nlrp12 in autoimmune-prone B6.Faslpr/lpr mice
Externí odkaz:
https://doaj.org/article/dd382a1d80b7478a870adf2346572e6d
Autor:
Zhuang Wang, Jing Zhu, Christopher M Reilly, Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Meeta Prakash, Thomas E Cecere, Sabrina Callaway, Sha Sun, S Ansar Ahmed, Xin M Luo
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/f2f4672125d043cea13be9e741e6f947
Autor:
Zhuang Wang, Bettina Heid, Ran Lu, Mohit Sachdeva, Michael R. Edwards, JingJing Ren, Thomas E. Cecere, Deena Khan, Taschua Jeboda, David G. Kirsch, Christopher M. Reilly, Rujuan Dai, S. Ansar Ahmed
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Dysregulated miRNAs have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Our previous study reported a substantial increase in three miRNAs located at the miR-183-96-182 cluster (miR-183C) in several autoimmune lupus-prone
Externí odkaz:
https://doaj.org/article/eb151dfa161c4f3db25223486d538a76
Autor:
Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Jing Zhu, Meeta Prakash, Thomas E. Cecere, Zhuang Wang, Sabrina Callaway, Sha Sun, Christopher M. Reilly, S. Ansar Ahmed, Xin M. Luo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Commensal bacteria and the immune system have a close and strong relationship that maintains a balance to control inflammation. Alterations of the microbiota, known as dysbiosis, can direct reactivity to self-antigens not only in the intestinal mucos
Externí odkaz:
https://doaj.org/article/d616c05d09714ae697accf2231edb1e4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Previous studies have reported that deletion of the transcription factor, early growth response protein 2 (EGR2), in normal C57BL/6 (B6) resulted in the development of lupus-like autoimmune disease. However, increased EGR2 expression has been noted i
Externí odkaz:
https://doaj.org/article/57ed76d973674108bfd16f1963a4c453
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Recent studies have shown that early growth response 2 (EGR2) is highly induced in activated T cells and regulates T cell functions. In normal C57BL/6 (B6) mice, deletion of EGR2 in lymphocytes results in the development of lupus-
Externí odkaz:
https://doaj.org/article/deffe2749cf04e099a1bbe5273540abd
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Hepatitis E is usually a self-limiting acute disease; however, during pregnancy, a severe form of fulminant hepatic failure and high mortality rate are associated with hepatitis E virus (HEV) infection. Increased levels of progesterone and HEV RNA ar
Externí odkaz:
https://doaj.org/article/c13bdb21805543b6ae5a9c89bb5cdd09
Autor:
Qinghui Mu, Husen Zhang, Xiaofeng Liao, Kaisen Lin, Hualan Liu, Michael R. Edwards, S. Ansar Ahmed, Ruoxi Yuan, Liwu Li, Thomas E. Cecere, David B. Branson, Jay L. Kirby, Poorna Goswami, Caroline M. Leeth, Kaitlin A. Read, Kenneth J. Oestreich, Miranda D. Vieson, Christopher M. Reilly, Xin M. Luo
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-12 (2017)
Abstract Background Systemic lupus erythematosus, characterized by persistent inflammation, is a complex autoimmune disorder with no known cure. Immunosuppressants used in treatment put patients at a higher risk of infections. New knowledge of diseas
Externí odkaz:
https://doaj.org/article/8cbdedad4872408eb4023944473cb663
Autor:
Harini Sooryanarain, C. Lynn Heffron, Hassan M. Mahsoub, Anna M. Hassebroek, Bo Wang, Debin Tian, S. Ansar Ahmed, Xiang-Jin Meng
Publikováno v:
J Virol
Hepatitis E virus (HEV) infection usually results in a self-limiting acute disease; however, in infected pregnant women, it is associated with increased mortality and fulminant hepatic failure. Estrogen is known to be elevated during pregnancy, and e
Autor:
Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Jing Zhu, Meeta Prakash, Thomas E Cecere, Zhuang Wang, Sabrina Callaway, Sha Sun, Christopher M Reilly, S Ansar Ahmed, Xin M Luo
Publikováno v:
Lupus Clinical Trials.