Zobrazeno 1 - 10
of 451
pro vyhledávání: '"S Ananth, Karumanchi"'
Autor:
Davina Zamanzadeh, Jeffrey Feng, Panayiotis Petousis, Arvind Vepa, Majid Sarrafzadeh, S. Ananth Karumanchi, Alex A. T. Bui, Ira Kurtz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Continuous renal replacement therapy (CRRT) is a form of dialysis prescribed to severely ill patients who cannot tolerate regular hemodialysis. However, as the patients are typically very ill to begin with, there is always uncertainty whethe
Externí odkaz:
https://doaj.org/article/e5fb0fef039340298cd81bd24ce0e8f4
Autor:
Erin J Ciampa, Padraich Flahardy, Harini Srinivasan, Christopher Jacobs, Linus Tsai, S Ananth Karumanchi, Samir M Parikh
Publikováno v:
eLife, Vol 12 (2023)
Most cases of preterm labor have unknown cause, and the burden of preterm birth is immense. Placental aging has been proposed to promote labor onset, but specific mechanisms remain elusive. We report findings stemming from unbiased transcriptomic ana
Externí odkaz:
https://doaj.org/article/62d975306489407bbe36c19be9c5333c
Autor:
Gena Guidry, Nicklaus A. Sparrow, Hyyat S. Marshall, Roberta De Souza Santos, Suman P. Bharath, Michael M. Gezalian, Margareta D. Pisarska, Jean-Philippe Vit, Scott A. Kelly, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Urinary tract infections (UTIs) are common and frequently precipitate delirium-like states. Advanced age coincident with the postmenopausal period is a risk factor for delirium following UTIs. We previously demonstrated a pathological role f
Externí odkaz:
https://doaj.org/article/757169c0da244f42bd6bf2223a53515d
Autor:
Faizan Anwar, Nicklaus A. Sparrow, Mohammad Harun Rashid, Gena Guidry, Michael M. Gezalian, Eric J. Ley, Maya Koronyo-Hamaoui, Itai Danovitch, E. Wesley Ely, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Acute neuropsychiatric impairments occur in over 70% of patients with acute lung injury. Mechanical ventilation is a well-known precipitant of acute lung injury and is strongly associated with the development of acute delirium and anxiety ph
Externí odkaz:
https://doaj.org/article/5b0cf2ca25d24b3cb45f3271401af387
Autor:
Sarah M. Davis, Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, Anastasia Khvorova
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 135-149 (2022)
Preeclampsia (PE) is a rising, potentially lethal complication of pregnancy. PE is driven primarily by the overexpression of placental soluble fms-like tyrosine kinase 1 (sFLT1), a validated diagnostic and prognostic marker of the disease when normal
Externí odkaz:
https://doaj.org/article/9a70cf9e7c9f406b9efc376a07ec4325
Publikováno v:
Hypertension in Pregnancy, Vol 41, Iss 2, Pp 99-106 (2022)
Placental growth factor (PlGF), a member of the vascular endothelial growth factor family of proteins regulating angiogenesis, has been shown to have acute vasodilatory effects on human resistance arteries. However, the acute hemodynamic effects of P
Externí odkaz:
https://doaj.org/article/3cd43e7e369c45a197c4654fad93d0e6
Autor:
Nicklaus A. Sparrow, Gena Guidry, Faizan Anwar, Sonja Darwish, Scott A. Kelly, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Prone positioning is an established treatment for severe acute lung injury conditions. Neuronal dysfunction frequently occurs with mechanical ventilation-induced acute lung injury (VILI) and clinically manifests as delirium. We previously reported a
Externí odkaz:
https://doaj.org/article/4e5d64dc193f46ca9b953edd23f804ca
Autor:
Mohammad Harun Rashid, Nicklaus A. Sparrow, Faizan Anwar, Gena Guidry, Ambart E. Covarrubias, Haoming Pang, Chandrakumar Bogguri, S. Ananth Karumanchi, Shouri Lahiri
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The
Externí odkaz:
https://doaj.org/article/27295915fdbf4affa8700bfa43899cca
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 9, Pp 702-708 (2021)
Abstract Outward remodeling of the maternal uterine circulation during pregnancy is essential for normal uteroplacental perfusion and pregnancy outcome. The physiological mechanism by which this process is regulated is unknown; we hypothesized that i
Externí odkaz:
https://doaj.org/article/d8fa980e65cd43158d8e4975e7ec4260
Autor:
Vincent Dupont, Anders H. Berg, Michifumi Yamashita, Chengqun Huang, Ambart E. Covarrubias, Shafat Ali, Aleksandr Stotland, Jennifer E. Van Eyk, Belinda Jim, Ravi Thadhani, S. Ananth Karumanchi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
To understand how kidney donation leads to an increased risk of preeclampsia, we studied pregnant outbred mice with prior uninephrectomy and compared them with sham-operated littermates carrying both kidneys. During pregnancy, uninephrectomized (UNx)
Externí odkaz:
https://doaj.org/article/117fb9c5cd9b44e290984322c39645aa