Zobrazeno 1 - 10
of 46
pro vyhledávání: '"S Aljoscha, Wahl"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 4, Pp 629-639 (2023)
Utilizing anaerobic metabolisms for the production of biotechnologically relevant products presents potential advantages, such as increased yields and reduced energy dissipation. However, lower energy dissipation may indicate that certain reactions a
Externí odkaz:
https://doaj.org/article/8c93bb8f0b5546ce9c848669f4f450e7
Autor:
Karel Olavarria, Yared O. Pijman, Ricardo Cabrera, Mark C. M. van Loosdrecht, S. Aljoscha Wahl
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The coupling of PHB generation with NADH reoxidation is required to generate PHB as a fermentation product. A fundamental trait to accomplish this feature is to express a functional NADH-preferring acetoacetyl-CoA reductase, engaged in PHB a
Externí odkaz:
https://doaj.org/article/488e8e01839d4771acfc70f5de3ccfb1
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Background Microbial metabolism is highly dependent on the environmental conditions. Especially, the substrate concentration, as well as oxygen availability, determine the metabolic rates. In large-scale bioreactors, microorganisms encounter
Externí odkaz:
https://doaj.org/article/f96b70d2606c4d789619c4484dae42c8
Autor:
David Lao-Martil, Koen J. A. Verhagen, Ana H. Valdeira Caetano, Ilse H. Pardijs, Natal A. W. van Riel, S. Aljoscha Wahl
Publikováno v:
Metabolites, Vol 13, Iss 1, p 88 (2023)
Microbial metabolism is strongly dependent on the environmental conditions. While these can be well controlled under laboratory conditions, large-scale bioreactors are characterized by inhomogeneities and consequently dynamic conditions for the organ
Externí odkaz:
https://doaj.org/article/3a62b617fbb6469797c7fc99152a0a72
Autor:
David Lao-Martil, Koen J. A. Verhagen, Joep P. J. Schmitz, Bas Teusink, S. Aljoscha Wahl, Natal A. W. van Riel
Publikováno v:
Metabolites, Vol 12, Iss 1, p 74 (2022)
Central carbon metabolism comprises the metabolic pathways in the cell that process nutrients into energy, building blocks and byproducts. To unravel the regulation of this network upon glucose perturbation, several metabolic models have been develop
Externí odkaz:
https://doaj.org/article/1359d294128b492c8b2aa93b12a75af8
Autor:
S. Aljoscha Wahl, Cristina Bernal Martinez, Zheng Zhao, Walter M. van Gulik, Mickel L. A. Jansen
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available. At low cultivation pH and high titers, the product transpor
Externí odkaz:
https://doaj.org/article/25112f72cf004793a766d9a57d82c126
Autor:
Robin Schumacher, S. Aljoscha Wahl
Publikováno v:
Metabolites, Vol 5, Iss 4, Pp 697-719 (2015)
The design of microbial production processes relies on rational choices for metabolic engineering of the production host and the process conditions. These require a systematic and quantitative understanding of cellular regulation. Therefore, a novel
Externí odkaz:
https://doaj.org/article/83ce3dee715341c7b5221ab3a9406ad9
Autor:
Johan H. van Heerden, Meike T. Wortel, Frank J. Bruggeman, Joseph J. Heijnen, Yves J.M. Bollen, Robert Planqué, Josephus Hulshof, Tom G. O’Toole, S. Aljoscha Wahl, Bas Teusink
Publikováno v:
Microbial Cell, Vol 1, Iss 3, Pp 103-106 (2015)
In the model eukaryote Saccharomyces cerevisiae, it has long been known that a functional trehalose pathway is indispensable for transitions to high glucose conditions. Upon addition of glucose, cells with a defect in trehalose 6-phosphate synthase (
Externí odkaz:
https://doaj.org/article/dd2ccf032fec4f26af023e85a24c081a
Autor:
B.M. Evers, Barbara M. Bakker, Theo Boer, Albert Gerding, S. Aljoscha Wahl, Mathilde Jalving, M. Rebecca Heiner-Fokkema, Dirk-Jan Reijngoud
Publikováno v:
Analytical Chemistry
Analytical Chemistry, 93(23), 8248-8256. AMER CHEMICAL SOC INC
Analytical Chemistry, 93(23)
Analytical Chemistry, 93(23), 8248-8256. AMER CHEMICAL SOC INC
Analytical Chemistry, 93(23)
C-13-isotope tracing is a frequently employed approach to study metabolic pathway activity. When combined with the subsequent quantification of absolute metabolite concentrations, this enables detailed characterization of the metabolome in biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648eef525090bd12a1e55768f81a2080
http://europepmc.org/articles/PMC8253487
http://europepmc.org/articles/PMC8253487
Autor:
David Lao-Martil, Koen J.A. Verhagen, Ana H. Valdeira Caetano, Ilse H. Pardijs, Natal A.W. van Riel, S. Aljoscha Wahl
Microbial metabolism is strongly dependent on the environmental conditions. While these can be well controlled under laboratory conditions, large-scale bioreactors are characterized by inhomogeneities and consequently dynamic conditions for the organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f975ffe957cc4a2612364dcea35bdbd5
https://doi.org/10.1101/2022.06.28.497175
https://doi.org/10.1101/2022.06.28.497175
