Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S Alison, Arnold"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targ
Externí odkaz:
https://doaj.org/article/0e288334ff9a41fda5a122dc76b4e68a
Autor:
Annemette Kjeldsen, Jack E. Kay, Scott Baxter, Stephen McColm, Cristina Serrano‐Amatriain, Scott Parker, Ellis Robb, S. Alison Arnold, Craig Gilmour, Anna Raper, Graeme Robertson, Robert Fleming, Brian O. Smith, Ian G. Fotheringham, John M. Christie, Leonardo Magneschi
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 7, Pp 2126-2139 (2022)
Summary The methylotrophic yeast Pichia pastoris is commonly used for the production of recombinant proteins at scale. The identification of an optimally overexpressing strain following transformation can be time and reagent consuming. Fluorescent re
Externí odkaz:
https://doaj.org/article/fb23b6d82d6f45a3b685a36c98b58246
Autor:
Graham R. Eastham, Gill Stephens, S. Alison Arnold, Joseph P. Webb, Scott Baxter, Stephen J. Hall
Publikováno v:
Microbiology
Citramalic acid is a central intermediate in a combined biocatalytic and chemocatalytic route to produce bio-based methylmethacrylate, the monomer used to manufacture Perspex and other high performance materials. We developed an engineered E. coli st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4527dfe1dfe628e71a60e55b9c2ef65
https://pubmed.ncbi.nlm.nih.gov/29231156
https://pubmed.ncbi.nlm.nih.gov/29231156
Publikováno v:
Process Biochemistry. 46:721-729
The effects of oxygen availability and induction culture biomass upon production of an industrially important monoamine oxidase (MAO) were investigated in fed-batch cultures of a recombinant E. coli. For each induction cell biomass 2 different oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841af16f6c03048e6911be64d4e09629
https://doi.org/10.1016/j.procbio.2010.11.019
https://doi.org/10.1016/j.procbio.2010.11.019
Publikováno v:
Enzyme and Microbial Technology. 36:621-628
The use of near infrared spectroscopy (NIRS) was investigated in the context of an efficient high cell density fed-batch industrial Pichia pastoris bioprocess for the production of a therapeutic mammalian protein. This process represented a considera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92876579cf821dde28dbc0d2551f6355
https://doi.org/10.1016/j.enzmictec.2003.12.016
https://doi.org/10.1016/j.enzmictec.2003.12.016
Publikováno v:
Biotechnology Letters. 25:257-260
Mid-infrared spectroscopy (MIRS) was used to simultaneously detect and predict concentrations of D-sorbitol and L-sorbose during a Gluconobacter suboxydans biotransformation. Quantitative models for both these compounds were developed for the entire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b925f8afcfe03f8c85c741bd52dcf9
https://doi.org/10.1023/a:1022351001284
https://doi.org/10.1023/a:1022351001284
Publikováno v:
Biotechnology Letters. 23:143-147
Near infrared spectroscopy (NIRS) was used to monitor an industrial bioprocess for the production of the antibiotic, tylosin, using a segmented modelling approach. Models were built over the entire time course of the fermentation from 0 to 150 h, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d339af92e1a50270e25bda082c4ca4
https://doi.org/10.1023/a:1010343828947
https://doi.org/10.1023/a:1010343828947
Autor:
S. Alison Arnold, Liliana Matheson, Linda M. Harvey, Brian McNeil, Pankaj Mohan, Seetharaman Vaidyanathan
Publikováno v:
Biotechnology and Bioengineering. 74:376-388
Access to real-time process information is desirable for consistent and efficient operation of bioprocesses. Near-infrared spectroscopy (NIRS) is known to have potential for providing real-time information on the quantitative levels of important biop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a296993ba2ba17dc5c119eb0e3ba512c
https://doi.org/10.1002/bit.1128
https://doi.org/10.1002/bit.1128
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02f4ec517b9ebdb4e33882525c405e7a
https://doi.org/10.1002/chin.200952260
https://doi.org/10.1002/chin.200952260
Publikováno v:
Critical reviews in biotechnology. 26(1)
The development of Near Infrared Spectroscopy has paralleled that of the PC, and the application of NIR in many industries has undergone explosive growth in recent years. This has been particularly apparent in the area of microbial and cell culture s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea1b6664d3b7f75debf7fba16a2c06b
https://pubmed.ncbi.nlm.nih.gov/16594523
https://pubmed.ncbi.nlm.nih.gov/16594523