Zobrazeno 1 - 10
of 52
pro vyhledávání: '"S A Stass"'
Publikováno v:
Gene Therapy. 7:1698-1705
Development of nonviral delivery systems is progressing toward a transfection efficiency sufficient to affect metabolic and neoplastic diseases in humans. Nevertheless, inadequate transfection efficiency of target cells with current nonviral systems
Autor:
Sherry Pierce, Madeleine Duvic, L. E. Robertson, Elihu H. Estey, Michael J. Keating, Susan O'Brien, S. A. Stass, Razelle Kurzrock, Hagop M. Kantarjian
Publikováno v:
Blood. 84:733-738
Mature T-cell lymphoproliferative disorders comprise a heterogenous group of diseases for which there is no standard therapy. These disorders are uncommon, and are usually treated similarly to their B- cell counterparts, but with less success. Nucleo
Publikováno v:
Blood. 84:279-286
Annexin VIII is a calcium-dependent phospholipid-binding protein previously identified as a blood anticoagulant based on in vitro studies. However, the physiologic function of annexin VIII remains unknown. In acute promyelocytic leukemia (APL) the an
Autor:
J Q, Guo, J Y, Lian, Y M, Xian, M S, Lee, A B, Deisseroth, S A, Stass, R E, Champlin, M, Talpaz, J Y, Wang, R B, Arlinghaus
Publikováno v:
Blood. 83:3629-3637
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder associated with the Philadelphia chromosome (Ph1) in more than 95% of these patients. The Ph1 and the resulting BCR-ABL fused genes are markers for this type of leukemia. In CML, the
Autor:
Hagop M. Kantarjian, Jennifer M. Trujillo, Emil J. Freireich, S. A. Stass, Issa F. Khouri, Albert B. Deisseroth, M. S. Lee, Richard E. Champlin, Moshe Talpaz
Publikováno v:
British Journal of Haematology. 82:708-714
The prognostic significance of detecting minimal residual disease by polymerase chain reaction (PCR) amplification of bcr/abl mRNA transcripts was investigated in 27 bone marrow samples from 20 patients with Philadelphia chromosome (Ph1) positive chr
Publikováno v:
Blood. 79:1802-1810
Since the translocation breakpoint t(15;17) (q22;q21) in acute promyelocytic leukemia (APL) occurs within the retinoic acid receptor- alpha (RARA) gene, the expression of many genes normally regulated by RARA may be affected by this translocation. To
Publikováno v:
Cancer research. 59(14)
Gene therapy transfer of angiostatin and endostatin represents an alternative method of delivering angiogenic polypeptide inhibitors. We examined whether liposomes complexed to plasmids encoding angiostatin or endostatin inhibited angiogenesis and th
Autor:
W, Grizzle, W W, Grody, W W, Noll, M E, Sobel, S A, Stass, T, Trainer, H, Travers, V, Weedn, K, Woodruff
Publikováno v:
Archives of pathologylaboratory medicine. 123(4)
As recipients of tissue and medical specimens, pathologists and other medical specialists regard themselves as stewards of patient tissues and consider it their duty to protect the best interests of both the individual patient and the public. The ste
Autor:
S A, Stass, J, Mixson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(12 Pt 2)
Genetic instability is a hallmark of cancer. Alterations in DNA through mutations, deletions, and translocations affect genes that are fundamental to normal cell growth differentiation and programmed cell death. Here, we discuss these alterations as
Publikováno v:
Cancer. 76(6)
There have been published reports on cytogenetic, immunophenotypic, and molecular changes at relapse in childhood acute lymphoblastic leukemia (ALL) including lineage switch and secondary leukemia. There are limited data, however, on the cytogenetic,