Zobrazeno 1 - 10
of 19
pro vyhledávání: '"S A Mizsak"'
Publikováno v:
Journal of Heterocyclic Chemistry. 34:295-299
The 1H and 13C nmr spectral assignments of [7bR]-N-[2-[(4,5,8,8a-tetrahydro-7-methyl-4-oxocyclo-propa[c]pyrrolo[3,2-e]indol-2(1H)-ylcarbonyl]-1H-indol-5-yl]-2-benzofurancarboxamide (Adozelesin) (1) are described. Complete and unambiguous assignments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa293d66cf344c34fefc66afb288e23b
https://doi.org/10.1002/jhet.5570340145
https://doi.org/10.1002/jhet.5570340145
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::025eb6e1eca559b93d2274ed32ca1660
https://doi.org/10.1002/chin.199731206
https://doi.org/10.1002/chin.199731206
Autor:
J J Vrbanac, Paul G. Pearson, P E Sanders, R T Streeper, Larry C. Wienkers, Z Zhao, S A Mizsak
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 27(11)
1. We have determined that 2,4-dipyrrolidinylpyrimidine (2,4-DPP), used as a model for studies of the metabolism of therapeutic agents containing this moiety, undergoes three characteristic hydroxylations when incubated with male rat liver microsomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7e5de145c917fb5c7f6cdeb5438c52
https://pubmed.ncbi.nlm.nih.gov/9413917
https://pubmed.ncbi.nlm.nih.gov/9413917
Autor:
J. E. Chin, Donald E. Ayer, Gordon L. Bundy, K. L. Belonga, Edward D. Hall, L. S. Banitt, K. L. Linseman, S A Mizsak, J. M. Tustin, John R. Palmer
Publikováno v:
Journal of medicinal chemistry. 38(21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7b385a200d07d19f00cb82d7c43d4e
https://pubmed.ncbi.nlm.nih.gov/7473542
https://pubmed.ncbi.nlm.nih.gov/7473542
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(3)
Tirilazad mesylate, a potent inhibitor of membrane lipid peroxidation in vitro, is under clinical development for the treatment of subarachnoid hemorrhage and head injury. In rat, tirilazad seems to be highly extracted and is cleared almost exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cce0e37ce1fc255e0627990b6b5ab502
https://pubmed.ncbi.nlm.nih.gov/7628305
https://pubmed.ncbi.nlm.nih.gov/7628305
Publikováno v:
ACS Symposium Series ISBN: 9780841218857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9901235346dee1ce0d20fc12d2a28adf
https://doi.org/10.1021/bk-1991-0443.ch033
https://doi.org/10.1021/bk-1991-0443.ch033
Publikováno v:
Planta Medica. 56:500-500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22951b5f940c27884fc79dac21fdb1a5
https://doi.org/10.1055/s-2006-961033
https://doi.org/10.1055/s-2006-961033
Publikováno v:
Journal of Medicinal Chemistry. 24:1487-1492
The preparation of 2"-deoxykanamycin B (12) and 2",3',4'-trideoxykanamycin B (14) from neamine (1) is described. Key intermediates in the synthesis of these 2"-deoxyaminoglycoside antibiotics are 3',4'-bis-O-(p-nitrobenzoyl)-1,2',3,6'-tetrakis-N-(tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbdc72ce105ad75a8742aaa8acd75b3
https://doi.org/10.1021/jm00144a023
https://doi.org/10.1021/jm00144a023
Publikováno v:
Journal of Biological Chemistry. 261:747-751
The gorgonian coral Pseudoplexaura porosa contains a lipoxygenase capable of converting exogenous arachidonic acid into (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid. The (8R)- (or 8-L-) configuration in this product, opposite to that observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb5fd6c52103d4a7c482eccd358e107
https://doi.org/10.1016/s0021-9258(17)36157-4
https://doi.org/10.1016/s0021-9258(17)36157-4
Autor:
W H, Darlington, D A, Constable, L, Baczynskyj, S A, Mizsak, T A, Scahill, L G, Dring, J M, McCall, J, Szmuszkovicz
Publikováno v:
Drug design and delivery. 1(3)
Metabolism of tazadolene (1), a novel non-opioid analgesic with antidepressant properties, affords the 4-hydroxy and 3-methoxy-4-hydroxy derivatives (phenyl ring) of the drug, and N-[2-(phenylmethylene)cyclohexyl]-beta-alanine (4). The isolation, ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28fe1355e2e1aa857a28017708468287
https://pubmed.ncbi.nlm.nih.gov/3509335
https://pubmed.ncbi.nlm.nih.gov/3509335