Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S A Mattai"'
High circulating elafin levels are associated with Crohn's disease-associated intestinal strictures.
Autor:
Jiani Wang, Christina Ortiz, Lindsey Fontenot, Ying Xie, Wendy Ho, S Anjani Mattai, David Q Shih, Hon Wai Koon
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231796 (2020)
BackgroundAntimicrobial peptide expression is associated with disease activity in inflammatory bowel disease (IBD) patients. IBD patients have abnormal expression of elafin, a human elastase-specific protease inhibitor and antimicrobial peptide. We d
Externí odkaz:
https://doaj.org/article/5bf9df99799348ad8ba254e231ee6dd8
Autor:
Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon
Publikováno v:
BMC Gastroenterology, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity. We hypothesize that serum cathelicidin
Externí odkaz:
https://doaj.org/article/138654daeefa44cbb3ab54720566b84e
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2
Autor:
Ying Xie, Lindsey Fontenot, Andrea Chupina Estrada, Becca Nelson, Jiani Wang, David Q. Shih, Wendy Ho, S. Anjani Mattai, Florian Rieder, Dane D. Jensen, Nigel W. Bunnett, Hon Wai Koon
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 14(4)
More than half of Crohn's disease patients develop intestinal fibrosis-induced intestinal strictures. Elafin is a human protease inhibitor that is down-regulated in the stricturing intestine of Crohn's disease patients. We investigated the efficacy o
Autor:
Ivy Ka Man Law, Hon Wai Koon, S. Anjani Mattai, Ying Xie, Riya Mukhopadhyay, David Q. Shih, Jiani Wang, Lindsey Fontenot, Christina Ortiz, Zhaoping Li
Publikováno v:
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Elafin is an antimicrobial and anti-inflammatory protein. We hypothesize that elafin expression correlates with diabetes. Among non-diabetic and prediabetic groups, men have significantly higher serum elafin levels than women. Men with type 2 diabete
Autor:
Philip Fleshner, Zhaoping Li, D Hoang-Ngoc Tran, Michelle Vu, David Q. Shih, S A Mattai, Michelle Cheng, Bowei Su, Stephan R. Targan, D Hoang-Yen Tran, Christina Ortiz, Samantha Ho, Richard L. Gallo, Ivy Ka Man Law, Dermot P.B. McGovern, Jung Eun Lee, Hon Wai Koon, Tamer Sallam, E Fisseha, Iordanes Karagiannides, Kyriaki Bakirtzi, Tressia C. Hing, Elaine C. Lee, Lori Robbins, Christine Shieh, Aristea Sideri
Publikováno v:
International journal of obesity (2005)
International journal of obesity (2005), vol 40, iss 9
International journal of obesity (2005), vol 40, iss 9
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity. We hypothesize that cathelicidin expression correla
Autor:
Guy A. Weiss, Hon Wai Koon, Wendy Ho, Precious Lacey, Daniel W. Hommes, S. Anjani Mattai, Angelos Oikonomopoulos, Christina Ha, Diana Hoang-Ngoc Tran
Publikováno v:
Gastroenterology. 150:S696
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 46(5)
Systemic lupus erythematosus is a chronic, multisystem, autoimmune disorder that primarily affects women. Morbidity and mortality have improved for lupus patients during the last 15 years. An increased risk of malignancy in patients with lupus has be