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Akademický článek

Ethical decision-making: the doctrine of sin and grace

Autor: S. P. Giles

Publikováno v: In die Skriflig, Vol 43, Iss 2, Pp 341-360 (2009)

Ethical decision-making presupposes the possession of a free will. Central to a discussion on reformed ethics is the question of the bounds of freedom of the will. The reformed tradition, along with the wider Christian tradition, affirms that the wil

Externí odkaz: https://doaj.org/article/35903a57697b4c58b512b7158f061087

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High bone mass phenotype in a cohort of patients with Osteogenesis Imperfecta caused due to BMP1 and C-propeptide cleavage variants in COL1A1

Autor: S. Cadden, S. Keigwin, Paul Arundel, D. Baker, Enrico Dall'Ara, E.H. Campanini, James A. Fernandes, Amaka C. Offiah, Meena Balasubramanian, N. Nicolaou, S N Giles, Nick Bishop

Publikováno v: Bone Reports, Vol 15, Iss, Pp 101102-(2021)
Bone Reports

Objectives\ud \ud Osteogenesis Imperfecta (OI) is a heterogeneous condition mainly characterised by bone fragility; extra-skeletal features in OI include blue sclerae, dentinogenesis imperfecta, skin laxity and joint hyper-extensibility. Most patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff43f713948cdbc171a7b22b28694b56
http://www.sciencedirect.com/science/article/pii/S2352187221003582

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Femoral neck fractures in osteogenesis imperfecta treated with bisphosphonates

Autor: M. C. Papanna, Michael J. Bell, S. N. Giles, James A. Fernandes, Suhayl I. Tafazal

Publikováno v: Journal of Children's Orthopaedics

Purpose Osteogenesis imperfecta (OI) is a condition characterised by bone fragility and multiple fractures, which cause considerable morbidity in the affected patients. Most cases are associated with mutations in one of the type I collagen genes. Rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0fa84c4aade0afaa69a7933b37b366
http://europepmc.org/articles/PMC5548034

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Evaluation of Quality of Life Outcomes Following Palliative Treatment of Bone Metastases with Magnetic Resonance-guided High Intensity Focused Ultrasound: An International Multicentre Study

Autor: D, Harding, S L, Giles, M R D, Brown, G R, Ter Haar, M, van den Bosch, L W, Bartels, Y-S, Kim, M, Deppe, N M, deSouza

Publikováno v: Clinical Oncology (Royal College of Radiologists (Great Britain)

Aims To determine quality of life (QoL) outcomes after palliation of pain from bone metastases using magnetic resonance-guided high intensity focused ultrasound (MR-guided HIFU), measured using the European Organization for Research and Treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8057fd873d74fe572cca14452ab5014d
https://pubmed.ncbi.nlm.nih.gov/29317145

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Peripheral fat metabolism during infusion of an exogenous triacylglycerol emulsion

Autor: S. L. Giles, M. L. Clark, Peter Arner, Rhys D. Evans, Lucinda K. M. Summers, Sandy M. Humphreys, J. S. Samra, Keith N. Frayn

Objective To test the hypothesis that intravenous infusion of lipid would bring about changes in adipose tissue metabolism, which would tend to spare net fat mobilization, and to attempt to identify the mediators of such responses. Design The triacyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c6bd8cf255da367c0975821ea0ba19
https://ora.ox.ac.uk/objects/uuid:921feeff-573e-4269-989a-59fd28322828

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Assessing myeloma bone disease with whole-body diffusion-weighted imaging: comparison with x-ray skeletal survey by region and relationship with laboratory estimates of disease burden

Autor: S L, Giles, N M, deSouza, D J, Collins, V A, Morgan, S, West, F E, Davies, G J, Morgan, C, Messiou

Publikováno v: Clinical Radiology

Aim To estimate and compare the extent of myeloma bone disease by skeletal region using whole-body diffusion-weighted imaging (WB-DWI) and skeletal survey (SS) and record interobserver agreement, and to investigate differences in imaging assessments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::caf5d0668a3af89726737b7f6d9d4b95
https://pubmed.ncbi.nlm.nih.gov/25799364

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Geographic clustering of an outer surface protein A mutant of Borrelia burgdorferi. Possible implications of multiple variants for Lyme disease persistence

Autor: Ruth R. Montgomery, S. S. Giles, L. L. Fu, Stephen E. Malawista, X.‐M. Wang

Publikováno v: Rheumatology. 39:537-541

DNA sequences encoding full-length outer surface protein (Osp) A were amplified from four joint fluid samples over 4.5 months from a patient with chronic Lyme arthritis, with a variant from wild type only found in sample 3. Rather than a mutation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c6418bd6e9411d583b186d87258f65
https://doi.org/10.1093/rheumatology/39.5.537

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