Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S A, Stoehr"'
Publikováno v:
The Journal of Immunology. 144:3936-3945
We have identified two major proteins in human neutrophils that are phosphorylated in vitro by protein kinase C (PKC) as lipocortins III and a fragment of a lipocortin-like 68-kDa protein. In electroporated cells, the 68-kDa protein was phosphorylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd380d135aa1d3ff9dbb9afa9e565b40
https://doi.org/10.4049/jimmunol.144.10.3936
https://doi.org/10.4049/jimmunol.144.10.3936
Publikováno v:
Journal of lipid research. 42(4)
Glycosphingolipids (GSLs), present in cell membranes, participate in a variety of biological functions. Although their exact role(s) may not be understood, it has been shown that 1) embryos lacking glucosylceramide synthase activity do not develop no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::571ea6b89ba67ffc0f7a07a4b97404e2
https://pubmed.ncbi.nlm.nih.gov/11290838
https://pubmed.ncbi.nlm.nih.gov/11290838
Autor:
D M Rock, Joann J Schmidt, Elizabeth Millerman, Thomas Charles Malone, David T. Connor, George P. Miljanich, Charles Taylor, S. Scott Bowersox, S J Stoehr, David J. Dooley, Balazs G. Szoke, Susan M. Lotarski, Rafferty Michael Francis, Yuntao Song, Mark G. Vartanian, Yong-Xiang Wang, Bruce D. Roth
Publikováno v:
Journal of medicinal chemistry. 43(19)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf74a0f6cfe82be4d4a1a6ce9c8017b0
https://pubmed.ncbi.nlm.nih.gov/11000000
https://pubmed.ncbi.nlm.nih.gov/11000000
Autor:
L Y, Hu, T R, Ryder, M F, Rafferty, K M, Siebers, T, Malone, A, Chatterjee, M R, Feng, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 17(1)
Several novel N-type voltage sensitive calcium channel blockers showed high affinity in the IMR32 assay and efficacy in the anti-writhing model. Herein, we describe the design, synthesis, SAR studies, biological data, physicochemical properties and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::382704345de2c1326eb0cae55033ad48
https://pubmed.ncbi.nlm.nih.gov/10928451
https://pubmed.ncbi.nlm.nih.gov/10928451
Autor:
T R, Ryder, L Y, Hu, M F, Rafferty, S M, Lotarski, D M, Rock, S J, Stoehr, C P, Taylor, M L, Weber, G P, Miljanich, E, Millerman, B G, Szoke
Publikováno v:
Drug design and discovery. 16(4)
Exploration of the SAR around the leucine side chain in a series of N,N-dialkyldipeptidylamines with potent functional activity at N-type VSCC is presented. A novel analog is disclosed which possesses improved aqueous solubility, in vivo activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::181b431799a8847399920bf609953e41
https://pubmed.ncbi.nlm.nih.gov/10807036
https://pubmed.ncbi.nlm.nih.gov/10807036
Autor:
F. Ghomashchi, Baldomero M. Olivera, S. J. Stoehr, D. J. Dooley, A. B. Giordani, Scott Naisbitt, Michael H. Gelb, J M McIntosh
Publikováno v:
The Journal of biological chemistry. 270(8)
We describe the purification and first biochemical characterization of an enzymatic activity in venom from the marine snail Conus magus. This enzyme, named conodipine-M, is a novel phospholipase A2 with a molecular mass of 13.6 kDa and is comprised o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c9e94d57c33c33cd779c31187fd656
https://pubmed.ncbi.nlm.nih.gov/7876086
https://pubmed.ncbi.nlm.nih.gov/7876086
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
We have identified two major proteins in human neutrophils that are phosphorylated in vitro by protein kinase C (PKC) as lipocortins III and a fragment of a lipocortin-like 68-kDa protein. In electroporated cells, the 68-kDa protein was phosphorylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6d602d7a798f1e021471a6e99bc2ee9
https://pubmed.ncbi.nlm.nih.gov/1692066
https://pubmed.ncbi.nlm.nih.gov/1692066
Autor:
J E Smolen, S J Stoehr
Publikováno v:
The Journal of Immunology. 134:1859-1865
Permeabilization of human neutrophils has been accomplished by using saponin, a cholesterol complexing agent, permitting experimental manipulation of the intracellular milieu. Access of ordinarily impermeable solutes, such as [14C]-inulin or [14C]-su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ea803781815803ecc8b41ce8363a66
https://doi.org/10.4049/jimmunol.134.3.1859
https://doi.org/10.4049/jimmunol.134.3.1859
Autor:
J E, Smolen, S J, Stoehr
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 134(3)
Permeabilization of human neutrophils has been accomplished by using saponin, a cholesterol complexing agent, permitting experimental manipulation of the intracellular milieu. Access of ordinarily impermeable solutes, such as [14C]-inulin or [14C]-su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da68e361cfda6d2c6c7015b197f9601a
https://pubmed.ncbi.nlm.nih.gov/3968435
https://pubmed.ncbi.nlm.nih.gov/3968435