Zobrazeno 1 - 10
of 29
pro vyhledávání: '"S A, Shurtleff"'
Autor:
Robert J. Ferry, Laura D Carbone, Sue C. Kaste, Harriet Surprise, Melissa M. Hudson, A. Qi, James M. Boyett, Elizabeth A. Lovorn, S. A. Shurtleff, Mary V. Relling, Karen Smith, C H Pui, K.K. Ness
Publikováno v:
Pediatric Blood & Cancer. 61:885-893
Background We sought to improve lumbar spine bone mineral density (LS-BMD) in long-term survivors of childhood acute lymphoblastic leukemia (ALL) using calcium and cholecalciferol supplementation.
Autor:
C. Cheng, Deqing Pei, Wing Leung, Monika L. Metzger, Sima Jeha, W P Bowman, John T. Sandlund, Jeffrey E. Rubnitz, Deepa Bhojwani, Elaine Coustan-Smith, Dario Campana, William E. Evans, Raul C. Ribeiro, C H Pui, Hiroto Inaba, Susana C. Raimondi, Mary V. Relling, Scott C. Howard, Mihaela Onciu, S. A. Shurtleff
Publikováno v:
Leukemia. 26:265-270
ETV6-RUNX1 fusion is the most common genetic aberration in childhood acute lymphoblastic leukemia (ALL). To evaluate whether outcomes for this drug-sensitive leukemia are improved by contemporary risk-directed therapy, we studied clinical features, r
Autor:
Edwin M. Horwitz, Renee Rencher, Mihaela Onciu, Mary Ellen Conley, S. A. Shurtleff, John T. Sandlund, Vanessa Howard, Wing Leung
Publikováno v:
Pediatric Blood & Cancer. 60:E85-E87
X-linked lymphoproliferative syndrome (XLP) is caused by mutations in SH2D1A, and is associated with overwhelming infectious mononucleosis, aplastic anemia, hypogammaglobulinemia, and B-cell lymphomas. However, the frequency of SH2D1A mutations in ma
Autor:
James R. Downing, Frederick G. Behm, S. A. Shurtleff, Jeffrey E. Rubnitz, Gerard Grosveld, Susan Mathew, C H Pui, Gaston K. Rivera, Michael L. Hancock, Susana C. Raimondi
Publikováno v:
Blood. 90:4559-4566
Although abnormalities involving the short arm of chromosome 12 (12p) are one of the most frequently observed rearrangements in childhood acute lymphoblastic leukemia (ALL), little is known about the frequency of different structural abnormalities an
Autor:
S C, Kaste, A, Qi, K, Smith, H, Surprise, E, Lovorn, J, Boyett, R J, Ferry, M V, Relling, S A, Shurtleff, C H, Pui, L, Carbone, M M, Hudson, K K, Ness
Publikováno v:
Pediatric bloodcancer. 61(5)
We sought to improve lumbar spine bone mineral density (LS-BMD) in long-term survivors of childhood acute lymphoblastic leukemia (ALL) using calcium and cholecalciferol supplementation.This double-blind, placebo-controlled trial randomized 275 partic
Autor:
S. A. Shurtleff, A. M. Curcio-Brint, Jeffrey E. Rubnitz, Andrew J. Carroll, James R. Downing, Frederick G. Behm, Susana C. Raimondi, RP Pinheiro
Publikováno v:
Blood. 87:4804-4808
MLL is fused to ENL or ELL in acute leukemias that contain t(ll;19)(q23;p13). Although ENL and ELL localize to chromosome 19, bands p13.3 and p13.1, respectively, these breakpoints are not always readily distinguished by standard cytogenetics. We the
Autor:
D G Gilliland, J N Davis, M F Roussell, S. A. Shurtleff, Gerard Grosveld, Weili Sun, A Buijs, James R. Downing, Todd R. Golub, Shari Meyers, Noel Lenny, Scott W. Hiebert
Publikováno v:
Molecular and Cellular Biology. 16:1349-1355
The t(12;21) translocation is present in up to 30% of childhood B-cell acute lymphoblastic and fuses a potential dimerization motif from the ets-related factor TEL to the N terminus of AML1. The t(12;21) translocation encodes a 93-kDa fusion protein
Autor:
Susana C. Raimondi, M L Slovak, Shari Meyers, Cheryl L. Willman, S Wolman, Scott W. Hiebert, S. A. Shurtleff, David R. Head, Andrew J. Carroll, Frederick G. Behm
Publikováno v:
Blood. 85:3695-3703
Inv(16)(p13q22) is one of the most frequent chromosomal rearrangements found in acute myelogenous leukemia (AML), representing approximately 16% of documented karyotypic abnormalities. The inv(16) breakpoints have been cloned and shown to involve the
Autor:
T, Okuda, S A, Shurtleff, M B, Valentine, S C, Raimondi, D R, Head, F, Behm, A M, Curcio-Brint, Q, Liu, C H, Pui, C J, Sherr
Publikováno v:
Blood. 85:2321-2330
The tandemly linked p16INK4aMTS1 and p15INK4b/MTS2 genes on chromosome 9, band p21 encode proteins that function as specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. This locus undergoes frequent bi-allelic deletion in human cancer
Autor:
Hazem Mahmoud, Michael L. Hancock, David R. Head, S. A. Shurtleff, Wayne L. Furman, C H Pui, John T. Sandlund, James R. Downing, Frederick G. Behm, Raul C. Ribeiro
Publikováno v:
Journal of Clinical Oncology. 12:909-915
PURPOSE Leukemic cell characteristics were analyzed in infants less than 1 year of age with acute lymphoblastic leukemia (ALL) to determine adverse prognostic factors that might explain the poor prognosis of this group. PATIENTS AND METHODS Treatment