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Akademický článek

BRCA1/2 mutation spectrum in Armenian patients with breast and ovarian cancers

Autor: Y. V. Belysheva, E. K. Bakaeva, A. R. Venina, A. A. Romanko, G. A. Raskin, A. P. Sokolenko, E. N. Suspitsin, A. A. Avetisyan, S. V. Orlov, E. N. Imyanitov

Publikováno v: Сибирский онкологический журнал, Vol 22, Iss 6, Pp 83-91 (2024)

The aim of the study was to compare the spectra of pathogenic BRCA1 and BRCA2 variants in patients with hereditary breast cancer (BC) and ovarian cancer (OC) from two groups of ethnic Armenians: Yerevan and cities of southern Russia.Material and Meth

Externí odkaz: https://doaj.org/article/fba47bd88bee4bc68054576336395c77

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Akademický článek

Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines

Autor: O. M. Drapkina, A. V. Kontsevaya, A. M. Kalinina, S. N. Avdeev, M. V. Agaltsov, L. I. Alekseeva, I. I. Almazova, E. Yu. Andreenko, D. N. Antipushina, Yu. A. Balanova, S. A. Berns, A. V. Budnevsky, V. V. Gainitdinova, A. A. Garanin, V. M. Gorbunov, A. Yu. Gorshkov, E. A. Grigorenko, B. Yu. Jonova, L. Yu. Drozdova, I. V. Druk, S. O. Eliashevich, M. S. Eliseev, G. Zh. Zharylkasynova, S. A. Zabrovskaya, A. E. Imaeva, U. K. Kamilova, A. D. Kaprin, Zh. D. Kobalava, D. V. Korsunsky, O. V. Kulikova, A. S. Kurekhyan, N. P. Kutishenko, E. A. Lavrenova, M. V. Lopatina, Yu. V. Lukina, M. M. Lukyanov, E. O. Lyusina, M. N. Mamedov, B. U. Mardanov, Yu. V. Mareev, S. Yu. Martsevich, N. P. Mitkovskaya, R. P. Myasnikov, D. V. Nebieridze, S. A. Orlov, K. G. Pereverzeva, O. E. Popovkina, V. I. Potievskaya, I. A. Skripnikova, M. I. Smirnova, T. M. Sooronbaev, N. V. Toroptsova, Zh. V. Khailova, V. E. Khoronenko, M. G. Chashchin, T. A. Chernik, S. A. Shalnova, M. M. Shapovalova, R. N. Shepel, A. F. Sheptulina, V. N. Shishkova, R. U. Yuldashova, I. S. Yavelov, S. S. Yakushin

Publikováno v: Кардиоваскулярная терапия и профилактика, Vol 23, Iss 3 (2024)

Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.

Externí odkaz: https://doaj.org/article/be1bf718a83641c9bbdec3186ac2921b

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Akademický článek

'Off-label' drugs: legal problems and socio-economic aspects of application practice

Autor: S. V. Russkikh, E. A. Tarasenko, L. I. Moskvicheva, S. A. Orlov, A. A. Tryakin, A. V. Vorobeva, O. A. Beneslavskaya, V. I. Makarova, E. A. Putilina, S. A. Utkin

Publikováno v: Фармация и фармакология (Пятигорск), Vol 11, Iss 2, Pp 149-160 (2023)

The aim of the work was to analyze Russian and foreign experience in the regulation and application practice of “off-label” drugs in order to develop recommendations on the optimization of their application in clinical practice.Material and metho

Externí odkaz: https://doaj.org/article/1147e4fc6d9a4fde8c1eee03e01db034

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Akademický článek

Possibilities of cell therapy in thoracic surgery

Autor: I. S. Polyakov, V. A. Porhanov, A. L. Kovalenko, I. V. Gilevich, O. N. Ponkina, V. S. Zima, D. D. Karal-ogly, S. V. Orlov, A. S. Sotnichenko, A. G. Zavgorodnyaya

Publikováno v: Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 30, Iss 1, Pp 27-36 (2023)

Introduction. Bronchial fistula often occurs after lung surgery. This is an extremely severe complication with high mortality. Despite the variety methods for the treatment of bronchial fistula, the results are not always effective. In our paper, we

Externí odkaz: https://doaj.org/article/b50a47a66ead42b894880b3f8ae12659

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Akademický článek

Molecular markers as predictors of response to perioperative chemotherapy in locally advanced gastric cancer

Autor: K. A. Oganyan, A. A. Musaelyan, S. V. Lapin, T. V. Kupenskaya, A. A. Sveсhkova, M. A. Belyaev, A. A. Zakharenko, S. V. Orlov

Publikováno v: Успехи молекулярной онкологии, Vol 10, Iss 1, Pp 40-48 (2023)

Introduction. Perioperative FLOT chemotherapy has improved prognosis in patients with locally advanced resectable gastric cancer (GC). However, in 80 % of cases, the tumor is resistant to the therapy, resulting in unnecessary toxicity and delayed sur

Externí odkaz: https://doaj.org/article/48b169fc192947978f9fe44ea90a9f2d

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Akademický článek

Cognitive-matrix analysis of research on primary health care development in the Russian Federation for the period from 2012 to 2022

Autor: S. A. Orlov, R. N. Shepel, D. V. Voshev, D. O. Savchenko, D. A. Gellekh, А. B. Gorlov, K. S. Mezhidov, M. V. Turlay, A. V. Sentsova, L. M. Zhamalov, A. V. Kontsevaya, O. M. Drapkina

Publikováno v: Кардиоваскулярная терапия и профилактика, Vol 22, Iss 9S (2023)

The distribution of publications posted in the Elibrary for the period from January 1, 2012 to December 31, 2022, in the structure of a cognitive matrix of taxonomic characteristics for the analysis and assessment of primary health care in the Russia

Externí odkaz: https://doaj.org/article/7e1f1d853ca64d50be243013f4720f00

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Akademický článek

Digital health literacy in primary care: a key driver of patient satisfaction in the era of digital transformation in healthcare

Autor: D. V. Voshev, I. M. Son, N. A. Vosheva, S. A. Orlov, K. S. Mezhidov, R. N. Shepel, O. M. Drapkina

Publikováno v: Кардиоваскулярная терапия и профилактика, Vol 22, Iss 9S (2023)

Aim. To analyze digital technologies in the primary health care system, as well as studying the impact of digital health literacy on patient satisfaction with the services provided.Material and methods. A study assessing patients' opinions on the dig

Externí odkaz: https://doaj.org/article/cc836783a71c45c4bb790e8061530763

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Akademický článek

Assessment of the effectiveness of surgical resections following tyrosine kinase inhibitor therapy in patients with EGFR-mutated stage III–IV lung adenocarcinoma

Autor: E. V. Levchenko, F. V. Moiseenko, S. V. Orlov, E. N. Imyanitov, A. E. Mikhnin, M. L. Gelfond, E. N. Slugin, S. M. Ergnyan, N. E. Levchenko, A. S. Zhabina, A. M. Ulitin, O. Yu. Mamontov, O. O. Lopushanskaya, E. V. Artemeva, A. I. Murtazin, V. I. Shabinskaya

Publikováno v: Сибирский онкологический журнал, Vol 22, Iss 1, Pp 5-14 (2023)

Objective. To assess the overall and disease-free survival rates in patients with EGFR-mutated lung adenocarcinoma, who underwent surgery after achieving the objective response to tyrosine kinase inhibitor (TKI) therapy.Material and Methods. The over

Externí odkaz: https://doaj.org/article/7336c9ed20724b46b7c9eb818dc1a744

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Akademický článek

Diagnostic and prognostic significance of detecting mutations in the BRAF, TERT, RAS, RET/PTC, PAX8/PPARG in the material of fine needle aspiration biopsy thyroid nodules in the IV cytological group (Bethesda, 2017)

Autor: A. A. Musaelyan, S. V. Lapin, V. D. Nazarov, E. S. Kozorezova, S. L. Vorobyev, S. V. Orlov

Publikováno v: Опухоли головы и шеи, Vol 12, Iss 2, Pp 71-78 (2022)

Introduction. Fine needle aspiration biopsy followed by cytological examination is the gold standard in the diagnosis of thyroid nodules. However, up to one third of cases represent an indeterminate result (Bethesda Thyroid Classification, 2017) III�

Externí odkaz: https://doaj.org/article/bda8c49f56f341f692685f4c13d6a75d

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Akademický článek

Immunological markers for predicting the response to immunotherapy in non-small cell lung cancer

Autor: A. A. Musaelyan, S. V. Lapin, M. A. Urtenova, S. V. Odintsova, I. V. Chistyakov, A. M. Ulitin, N. T. Ismanbaev, A. L. Akopov, S. V. Orlov

Publikováno v: Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 79-88 (2022)

Itroduction. Immune checkpoint inhibitors have become the standard of care for patients with advanced non-small cell lung cancer. However, despite the determination of programmed death-ligand 1 expression in clinical practice, which determines the ef

Externí odkaz: https://doaj.org/article/3ad6732d802f458d83f8727e411fce75

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