Zobrazeno 1 - 10
of 50
pro vyhledávání: '"S A, Matlin"'
Autor:
C. C. Benz, T. J. Ormsby, A. J. Rogers, Maria Elizabeth Tiritan, X. S. Liang, C. L. Webber, S. A. Matlin
Publikováno v:
Investigational New Drugs. 13:181-186
Preclinical and clinical studies have pointed to the antitumor potential of the naturally occurring polyphenolic binaphthyl dialdehyde, gossypol, as well as its purified (-,+) enantiomers. To explore further the antitumor properties of this multifunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b9c0ce8503197478969c53760ad109
https://doi.org/10.1007/bf00873798
https://doi.org/10.1007/bf00873798
Autor:
M J Cosentino, S A Matlin
Publikováno v:
Expert opinion on investigational drugs. 6(6)
To date, the current methods of male contraception are limited to condoms, coitus interruptus and vasectomy, all of which are beset with difficulties. The condom is inconvenient, dulls sensation, and although somewhat effective against sexually trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aecfa6c44fe1b4ce58561d5b10b510a
https://pubmed.ncbi.nlm.nih.gov/15989632
https://pubmed.ncbi.nlm.nih.gov/15989632
Publikováno v:
Chirality. 9(2)
The enantiomeric resolution of a series of N-arylamides was examined on amylose tris[(S)-1-phenylethylcarbamate] coated onto aminopropylated 7 microns silica with 500 A diameter pores and on naked silica 5 microns particle size with 500 A diameter po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08b5706fcd8818c4675969e3d1e0f75b
https://pubmed.ncbi.nlm.nih.gov/9134693
https://pubmed.ncbi.nlm.nih.gov/9134693
Publikováno v:
Journal of andrology. 16(2)
We had previously found that 2,4-diaminopyrimidines affected spermatogenesis, possibly through the inhibition of testicular dihydrofolate reductase (DHFR). The current study examined the effects of etoprine, a highly lipophilic 2,4-diaminopyrimidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3578651f218c6d588efbc8c0217c949a
https://pubmed.ncbi.nlm.nih.gov/7559148
https://pubmed.ncbi.nlm.nih.gov/7559148
Publikováno v:
Archives of medical research. 24(2)
Gossypol, a natural racemic mixture with action on NADP- and NAD-oxidoreductases from diverse species, has been proposed as a possible antiamebic medication considering several of its pharmacological properties. In this study it was found that malic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::728295c8748dd98d244b94a850e914f1
https://pubmed.ncbi.nlm.nih.gov/8274846
https://pubmed.ncbi.nlm.nih.gov/8274846
Publikováno v:
Archives of medical research. 23(2)
Gossypol has an in vitro antiamebic effect, which is 11,39, and 980 times more potent than emetime, metronidazole and diiodohydroxyquinolein, respectively, on five Entamoeba histolytica axenic strains. The trophozoite NADP-dependent malic enzyme and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3a5af530ddecd5a869079d52317bece
https://pubmed.ncbi.nlm.nih.gov/1340324
https://pubmed.ncbi.nlm.nih.gov/1340324
Publikováno v:
Proceedings of the Western Pharmacology Society. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::001d9c120acdfec8a8fde4bf4b5df32a
https://pubmed.ncbi.nlm.nih.gov/1788315
https://pubmed.ncbi.nlm.nih.gov/1788315
Autor:
S. A. Matlin, K. Barron
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c2d6c9ea114fbe7bb6c22960a73f112
https://doi.org/10.1002/chin.199049163
https://doi.org/10.1002/chin.199049163
Autor:
C C, Benz, M A, Keniry, J M, Ford, A J, Townsend, F W, Cox, S, Palayoor, S A, Matlin, W N, Hait, K H, Cowan
Publikováno v:
Molecular pharmacology. 37(6)
Racemic gossypol has been shown to have antitumor properties that may be due to its ability to uncouple tumor mitochondria or to its inhibitory effects on a variety of nonmitochondrial enzymes. We have studied the antimitochondrial and enzyme-inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::418f6d81b7f0192af49d27cd25040c9a
https://pubmed.ncbi.nlm.nih.gov/2193225
https://pubmed.ncbi.nlm.nih.gov/2193225