Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S A, Dorrbecker"'
Publikováno v:
Developmental Pharmacology and Therapeutics. 11:109-117
We studied the pharmacokinetics of caffeine in the pregnant New Zealand White rabbit, using two methods of drug administration. Ten rabbits that received a continuous intravenous infusion of caffeine (8-22 mg/kg.day) through 29 days of gestation exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66234139bee54517f263f01e9162ed89
https://doi.org/10.1159/000457675
https://doi.org/10.1159/000457675
Publikováno v:
Developmental Pharmacology and Therapeutics. 11:118-124
Twenty-three New Zealand White rabbits received a continuous intravenous infusion of caffeine during gestation. The amniotic fluid/maternal plasma concentration ratio was higher for caffeine than for its major metabolite, paraxanthine, throughout ges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b8fde4550d6648dbf6d934286aba0d6
https://doi.org/10.1159/000457676
https://doi.org/10.1159/000457676
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(1)
The metabolism and disposition of the bronchodilator, N-t-butylarterenol (tBA) and its di-p-toluate ester (bitolterol) were compared in the rat. Radioactivity was preferentially retained in lungs of rats compared with heart and blood after iv medicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::898dd88cca7b2f65461bc491dacb9b25
https://pubmed.ncbi.nlm.nih.gov/3403
https://pubmed.ncbi.nlm.nih.gov/3403
Publikováno v:
Developmental pharmacology and therapeutics. 11(2)
Twenty-three New Zealand White rabbits received a continuous intravenous infusion of caffeine during gestation. The amniotic fluid/maternal plasma concentration ratio was higher for caffeine than for its major metabolite, paraxanthine, throughout ges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::343a35f2e249d4094d6bbf137b700d00
https://pubmed.ncbi.nlm.nih.gov/3371146
https://pubmed.ncbi.nlm.nih.gov/3371146
Autor:
L, Shargel, S A, Dorrbecker
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(1)
The metabolism and disposition of bitolterol, the di-p-toluate ester of N-t-butylarterenol (tBA) was studied in man after a single oral dose and in dog after intraduodenal, iv, or oral administration. The mean (+/- SE) peak plasma radioactivity in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6b8c8d762da15fa8dbbdfb6baf9e260
https://pubmed.ncbi.nlm.nih.gov/3404
https://pubmed.ncbi.nlm.nih.gov/3404