Výsledky vyhledávání - "S A, Chuvpilo"

Antibodies to the N-Terminal Domain of Angiotensin-Converting Enzyme (ACE2) That Block Its Interaction with SARS-CoV-2 S Protein

Autor: V G, Krut, I V, Astrakhantseva, S A, Chuvpilo, G A, Efimov, S G, Ambaryan, M S, Drutskaya, S A, Nedospasov

Publikováno v: Doklady. Biochemistry and Biophysics

SARS-CoV-2 is a new coronavirus that is the cause of COVID-19 pandemic. To enter the cell, the virus interacts via its surface S protein with angiotensin-converting enzyme 2 (ACE2), the main entry receptor on the cell membrane. Most of protective ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa536ca6eb676a6ec20fed01315e64ce
http://europepmc.org/articles/PMC8649309

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Generation and Evaluation of Bispecific Anti-TNF Antibodies Based on Single-Chain VHH Domains

Autor: S. A. Chuvpilo, D. V. Yanvarev, V. V. Mokhonov, Marina S. Drutskaya, Kamar-Sulu N. Atretkhany, Sergei A. Nedospasov, M. A. Nosenko, Sergei Tillib

Publikováno v: Methods in Molecular Biology ISBN: 9781071611296

Systemic cytokine inhibition may be an effective therapeutic strategy for several autoimmune diseases. However, recent studies suggest that tissue or cell type-specific targeting of certain cytokines, including TNF, may have distinct advantages and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc057945f94843fe00560a092c7e2730
https://doi.org/10.1007/978-1-0716-1130-2_7

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[Model polycistron operon for studying conjugated translation in E. coli cells. The role of a stream of ribosomes]

Autor: V V, Kravchenko, V V, Shamin, I P, Gileva, V A, Likhoshvaĭ, S K, Korzhenevskiĭ, V N, Dobrynin, S A, Filippov, S A, Chuvpilo, V G, Korobko

Publikováno v: Bioorganicheskaia khimiia. 16(12)

The role of "stream" of ribosomes upon translation of polycistronic mRNAs has been studied using an artificial polycistron. It has been found that the levels of activation of cistron Ci + 1 out of two adjacent cistrons (Ci and Ci + 1) depends, in add

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e3685e4ae1417db0f0cdb2c26fe65fda
https://pubmed.ncbi.nlm.nih.gov/2128600

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[Synthetic promotor P25 of bacteriophage T5 and its functional hybrids with the model promotor of Escherichia coli]

Autor: V N, Dobrynin, V G, Korobko, S A, Filippov, S A, Chuvpilo, E F, Boldyreva

Publikováno v: Doklady Akademii nauk SSSR. 274(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6f8f3938124dfe78c339bb35982e7174
https://pubmed.ncbi.nlm.nih.gov/6323111

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Synthesis of a model promoter for gene expression in Escherichia coli

Autor: V N, Dobrynin, V G, Korobko, I V, Severtsova, N S, Bystrov, S A, Chuvpilo, M N, Kolosov

Publikováno v: Nucleic acids symposium series. (7)

We have synthesized a 67-membered double-stranded DNA containing putative initiation sites for transcription and translation in E. coli. Among the potential applications of this DNA are construction of artificial genes, cloning of foreign genes in E.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72a6e81d170865ac73a7ca1c1ce63775
https://pubmed.ncbi.nlm.nih.gov/6265875

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[The vector containing a signal for specific degradation of chimeric proteins. Synthesis of [Leu5]enkephalin using enteropeptidase]

Autor: V N, Dobrynin, E F, Boldyreva, S A, Filippov, S A, Chuvpilo, V G, Korobko

Publikováno v: Bioorganicheskaia khimiia. 13(1)

A plasmid vector (pEK1) coding, in framework of beta-galactosidase gene, for the amino acid sequence (Asp)4Lys which is recognized by bovine enteropeptidase has been constructed. Using this vector and chemically synthesized DNA coding for the [Leu5]-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d1f033356f5f3504a6f50b82698c0dc
https://pubmed.ncbi.nlm.nih.gov/3551962

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