Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S A, Ahrendt"'
Publikováno v:
Clinics in Liver Disease. 5:191-218
Despite overall advances in the ability to diagnose and treat patients with cholangiocarcinoma, the prognosis for patients with this malignancy remains poor. Further improvements in the survival of patients with cholangiocarcinoma will come with the
Autor:
S A, Ahrendt, P A, Decker, E A, Alawi, Y R, Zhu Yr, M, Sanchez-Cespedes, S C, Yang, G B, Haasler, A, Kajdacsy-Balla, M J, Demeure, D, Sidransky
Publikováno v:
Cancer. 92(6)
The majority of lung carcinoma cases occur in current or former smokers. K-ras gene mutations are common in lung adenocarcinoma and have been associated with cigarette smoking, asbestos exposure, and female gender.In the current study, the authors ex
Publikováno v:
Cancer research. 61(22)
The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) removes mutagenic adducts from the O6 position of guanine, thereby protecting the genome against G to A transition mutations. MGMT is inactivated by promoter hypermethylation in man
Autor:
L, Xu, J, Chow, J, Bonacum, C, Eisenberger, S A, Ahrendt, M, Spafford, L, Wu, S M, Lee, S, Piantadosi, M S, Tockman, D, Sidransky, J, Jen
Publikováno v:
International journal of cancer. 91(2)
We surveyed the occurrence of novel alleles at microsatellite sequences in non-small cell lung cancers (NSCLC) using 61 tetranucleotide repeat markers. The presence of at least one new allele, consistent with microsatellite instability (MSI), was obs
Publikováno v:
Cancer research. 60(12)
Epidemiological studies have demonstrated a strong association between tobacco use and lung cancer; however, the genetic targets of these carcinogens and the role of other environmental agents in this process have yet to be defined. We examined the c
Publikováno v:
Cancer research. 60(9)
Microsatellite alterations are useful clonal markers for the early detection of cancer. An increase in microsatellite instability has been observed at certain tetranucleotide repeat markers (AAAGn) in lung, head and neck, and bladder cancer. However,
Publikováno v:
The American surgeon. 65(8)
The safe performance of a right hepatic lobectomy requires adequate exposure of the hepatic veins and of the suprahepatic vena cava. An extended subcostal or midline incision is commonly used to provide exposure for this operation. The technique for
Publikováno v:
Journal of the American College of Surgeons. 189(1)
Evaluation of suspected biliary obstruction has traditionally involved a variety of imaging modalities including ultrasound, CT, and invasive cholangiography. These techniques have limitations because of poor visualization of intraductal stones (ultr
Publikováno v:
The American surgeon. 64(7)
Intestinal infarction remains a devastating event despite improvements in clinical recognition as well as diagnostic and therapeutic modalities. Recent changes in the etiology of this disease have not been examined. A retrospective review of 121 cons
Autor:
K, Okami, L, Wu, G, Riggins, P, Cairns, M, Goggins, E, Evron, N, Halachmi, S A, Ahrendt, A L, Reed, W, Hilgers, S E, Kern, W M, Koch, D, Sidransky, J, Jen
Publikováno v:
Cancer research. 58(3)
PTEN/MMAC1 is a candidate tumor suppressor gene recently identified at chromosomal band 10q23. It is mutated in sporadic brain, breast, and prostate cancer and in the germ line of patients with hereditary Cowden disease. We searched for genetic alter