Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sławomir Mandziuk"'
Autor:
Sara Janowska, Dmytro Khylyuk, Anna Bielawska, Anna Szymanowska, Agnieszka Gornowicz, Krzysztof Bielawski, Jarosław Noworól, Sławomir Mandziuk, Monika Wujec
Publikováno v:
Molecules, Vol 27, Iss 6, p 1814 (2022)
We designed and synthesized the 1,3,4-thiadiazole derivatives differing in the structure of the substituents in C2 and C5 positions. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and MDA-MB-231
Externí odkaz:
https://doaj.org/article/870e9885ca5947bfa0e0d5325bceb542
Autor:
Magdalena Izdebska, Mariola Herbet, Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Agnieszka Korga, Marcin Sysa, Magdalena Iwan, Dorota Natorska-Chomicka, Ewa Poleszak, Andrzej Wróbel, Sławomir Mandziuk, Jarosław Dudka
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose: The aim of this study was to evaluate the effect of resveratrol on de novo lipogenesis in HepG2 cells caused by high glucose concentrations. Increased lipogenesis in the liver is the main reason for the development of nonalcoholic fatty live
Externí odkaz:
https://doaj.org/article/54b313a3eb6240e0baa79e944fcf79aa
Autor:
Aleksandra Szopa, Karolina Bogatko, Mariola Herbet, Anna Serefko, Marta Ostrowska, Sylwia Wośko, Katarzyna Świąder, Bernadeta Szewczyk, Aleksandra Wlaź, Piotr Skałecki, Andrzej Wróbel, Sławomir Mandziuk, Aleksandra Pochodyła, Anna Kudela, Jarosław Dudka, Maria Radziwoń-Zaleska, Piotr Wlaź, Ewa Poleszak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1840 (2021)
The purpose of the study was to investigate whether the co-administration of Mg2+ and Zn2+ with selective A1 and A2A receptor antagonists might be an interesting antidepressant strategy. Forced swim, tail suspension, and spontaneous locomotor motilit
Externí odkaz:
https://doaj.org/article/565d8903ced440b696841165fba7d72a
Publikováno v:
Bioorganic Chemistry. 133:106398
Autor:
Jakub Krzysztof Gałązka, Marcin Czeczelewski, Tomasz Kucharczyk, Katarzyna Szklener, Sławomir Mańdziuk
Publikováno v:
Archives of Medical Science, Vol 20, Iss 1, Pp 313-316 (2024)
Introduction In this retrospective study, the authors evaluated whether obesity-induced immunomodulation impacts the expression of programmed death ligand-1 (PD-1L) in lung cancer cells. Methods A retrospective cross-sectional study was performed. T
Externí odkaz:
https://doaj.org/article/07fa8573e210490ca4b01c539996580e
Autor:
Mateusz Bilski, Katarzyna Szklener, Sebastian Szklener, Anna Rudzińska, Natalia Kluz, Jakub Klas, Anna Rodzajewska, Weronika Kuryło, Mateusz Korga, Izabela Baranowska, Sławomir Mańdziuk
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionEssential tremor (ET) is the most common movement disorder in adults, with an estimated incidence of up to 1% of the population and 5% of people older than 65 years of age. ET is manifested primarily by bilateral postural and kinetic trem
Externí odkaz:
https://doaj.org/article/5f400b77de3f4c7bab4db64348a94480
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma (GBM) represents a significant therapeutic challenge due to its aggressive nature. Tumor Treating Fields (TTFields) present a promising approach to GBM therapy. The primary mechanism of TTFields, an antimitotic effect, alongside numerous
Externí odkaz:
https://doaj.org/article/efb705e18d19405fb73f0efe54bfa470
Autor:
Jaroslaw Szponar, Agnieszka Gorska, Marta Ostrowska-Lesko, Agnieszka Korga-Plewko, Michal Tchorz, Erwin Ciechanski, Anna Dabrowska, Ewa Poleszak, Franciszek Burdan, Jaroslaw Dudka, Marek Murias, Slawomir Mandziuk
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2219 (2024)
Late cardiotoxicity is a formidable challenge in anthracycline-based anticancer treatments. Previous research hypothesized that co-administration of carvedilol (CVD) and dexrazoxane (DEX) might provide superior protection against doxorubicin (DOX)-in
Externí odkaz:
https://doaj.org/article/ba9b79ff7144444a9da2828e5e5386f8
Publikováno v:
Journal of Pre-Clinical and Clinical Research, Vol 16, Iss 3, Pp 85-89 (2022)
Non-specific focal lesions in the central nervous system pose diagnostic and therapeutic challenges. Moreover, the prognosis, depending on the lesion etiology, can be extremely varied from mild and potentially curable to extremely severe and untreata
Externí odkaz:
https://doaj.org/article/0f71a474287146d094c268f13558622a
Autor:
Barbara Madej-Czerwonka, Małgorzata Piasecka-Twaróg, Sławomir Mandziuk, null Monika Cendrowska-Pinkosz
Publikováno v:
Current Issues of Pharmacy and Medical Sciences. 26:127-130
Fracture of the proximal end of the femur is one of the most common fractures in elderly patients. Worldwide, this type of fracture occurs in 2.5 m of people annually including approximately 30, 000 Poles. It usually occurs as a complication of osteo