Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sławomir J Terlikowski"'
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 48, Iss 3, Pp 319-322 (2010)
Endometrial cancer is the most common gynecologic malignancy in more developed countries. Approximately 75% of cases are diagnosed at an early stage with a tumor confined to the uterine corpus. Although most patients are cured by surgery alone, about
Externí odkaz:
https://doaj.org/article/3eb2a58d132640ebac73b0cc5ac489a0
Autor:
Wiesława Niklińska, Oksana Kowalczuk, Sławomir J Terlikowski, Bozena Dobrzycka, Lech Chyczewski, Marek Kulikowski
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 47, Iss 2, Pp 221-224 (2009)
RAS genes are the most frequently mutated oncogenes detected in human cancer. In this study we analyzed the presence of mutations at codon 12 of the KRAS gene in 78 women with ovarian tumor, including 64 invasive ovarian cancers and 14 borderline ova
Externí odkaz:
https://doaj.org/article/9692b76c30474300b4aa6eac89765859
Autor:
Wiesława Niklińska, Oksana Kowalczuk, Andrzej Mazurek, Sławomir J Terlikowski, Bozena Dobrzycka, Lech Chyczewski, Marek Kulikowski
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 47, Iss 1, Pp 65-68 (2009)
The aim of this study was to examine the prevalence and clinicopathological significance of KRAS point mutation in endometrial hyperplasia and carcinoma. We analysed KRAS in 11 cases of complex atypical hyperplasia and in 49 endometrial carcinomas us
Externí odkaz:
https://doaj.org/article/3e6628f3ab474840a9fe5bed49ce164a
Publikováno v:
Endokrynologia Polska. 60(3)
Under physiological conditions, angiogenesis is routinely observed in the uterus. Multiple lines of evidence suggest that estrogen directly modulates angiogenesis via effects on endothelial cells. A clear association between estrogen, estrogen recept
Publikováno v:
Roczniki Akademii Medycznej w Bialymstoku (1995). 47
In accordance with presented results and clinical observation it should be assumed that basic phenomena resulting in clinical sign of preeclampsia take place already in implantation and embryogenesis. Abnormal trophoblastic infiltrations and changes
Autor:
Sławomir J. Terlikowski
Publikováno v:
Toxicology. 174(3)
Tumor necrosis factor (TNF-alpha) is a cytokine possessing antitumor and immunomodulatory properties. The studies reviewed in the present paper evaluate the effect of intratumor or intraperitoneal (i.t./i.p.) injections of human recombinant TNF-alpha
Autor:
Magdalena Garbowicz, Piotr S Bernaczyk, Slawomir J Terlikowski, Bozena Dobrzycka, Jacek Niklinski, Lech Chyczewski, Marek Kulikowski
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 48, Iss 4, Pp 678-681 (2011)
Apoptosis may occur via a death receptor-dependent or independent (mitochondrial) pathway. The mitochondrial pathway is regulated by small molecules, such as smac/Diablo, which activates caspase cascades. This study examined smac/DIABLO expression in
Externí odkaz:
https://doaj.org/article/5421d7156f224e14be8d963324676972
Autor:
Jacek Nikliński, Piotr S Bernaczyk, Wieslawa Niklińska, Magdalena Garbowicz, Slawomir J Terlikowski, Bozena Dobrzycka, Maciej Kinalski, Lech Chyczewski
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 47, Iss 4, Pp 609-613 (2010)
The aim of the present study was to characterize the expression pattern of tumor necrosis factor (TNF)-alpha and its receptors (TNF-Rs) in the epithelial ovarian cancer (EOC) and compare these results with the outcome of 126 patients. Presence of TNF
Externí odkaz:
https://doaj.org/article/3d4fe53e08a443b49bc63527b536764b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3495 (2021)
Our increased understanding of tumour biology gained over the last few years has led to the development of targeted molecular therapies, e.g., vascular endothelial growth factor A (VEGF-A) antagonists, poly[ADP-ribose] polymerase 1 (PARP1) inhibitors
Externí odkaz:
https://doaj.org/article/a4cccba1522a425f8b356455e0bbd8e9